Rchr
J-GLOBAL ID:201301002769531070   Update date: Sep. 23, 2024

Kamatari Yuji O.

カマタリ ユウジ | Kamatari Yuji O.
Affiliation and department:
Job title: 助教
Other affiliations (2):
  • 連合獣医学研究科  助教
  • 連合獣医学研究科  助教
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/70342772.ja.html
Research field  (1): Biophysics
Research keywords  (26): rational drug design ,  prion disease ,  Neurodegeneration ,  NMR ,  structural biology ,  protein dynamics ,  protein folding ,  protein ,  ダイナミクス ,  リゾチーム ,  揺らぎ ,  オリゴマー ,  高圧NMR ,  中間体 ,  安定性 ,  準安定状態 ,  高圧 ,  圧力 ,  アミロイド ,  巻き戻り ,  凝集 ,  NMR ,  蛋白質 ,  脳神経変性疾患 ,  生物物理学 ,  プリオン
Research theme for competitive and other funds  (18):
  • 2020 - 2023 旋毛虫分泌タンパク質による宿主筋肉細胞変異の分子生物学的および構造生物学的解析
  • 2020 - 2023 Construction of the pharmacophore model of antiprion compounds for development of a novel therapeutic agent
  • 2017 - 2023 凝集誘起発光イメージングで「観る」プリオンタンパク質オリゴマーの形成・伝播機構
  • 2020 - 2022 犬の変性性脊髄症を起こす変異SOD1蛋白質の立体構造解析と治療基盤の構築
  • 2015 - 2018 複数の抗原を特異的に認識する抗体の抗原認識機構の解明
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Papers (98):
  • Maho Sakaki, Yuji Kamatari, Akira Kurisaki, Masayuki Funaba, Osamu Hashimoto. Activin E upregulates uncoupling protein 1 and fibroblast growth factor 21 in brown adipocytes. Molecular and Cellular Endocrinology. 2024. 592. 112326-112326
  • Sora Nozaki, Masanori Hijioka, Xiaopeng Wen, Natsumi Iwashita, Junya Namba, Yoshiaki Nomura, Aoi Nakanishi, Soichiro Kitazawa, Ryo Honda, Yuji O. Kamatari, et al. Galantamine suppresses α-synuclein aggregation by inducing autophagy via the activation of α7 nicotinic acetylcholine receptors. Journal of Pharmacological Sciences. 2024
  • Yoko Hirata, Hiroshi Takemori, Kyoji Furuta, Yuji O. Kamatari, Makoto Sawada. Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T. Current Research in Pharmacology and Drug Discovery. 2024. 7. 100196-100196
  • Saho Furukawa, Kyoka Kawaguchi, Kotomi Chikama, Ryohei Yamada, Yuji O. Kamatari, Lee Wah Lim, Hiroko Koyama, Yasuo Inoshima, Mitsushi J. Ikemoto, Saishi Yoshida, et al. Simple methods for measuring milk exosomes using fluorescent compound GIF-2250/2276. Biochemical and Biophysical Research Communications. 2024. 149505-149505
  • Yoko Hirata, Tomohiro Hashimoto, Kaori Ando, Yuji O Kamatari, Hiroshi Takemori, Kyoji Furuta. Structural features localizing the ferroptosis inhibitor GIF-2197-r to lysosomes. RSC advances. 2023. 13. 46. 32276-32281
more...
MISC (42):
  • 工藤優大, 藤田芽衣, 吉野雄太, 鎌足雄司, 田中義正, 石川岳志, 藤本直浩, 岡田卓哉, 豊岡尚樹, 遠藤智史, et al. がんアジュバント薬の開発を指向したオートファジー阻害剤の創製研究. 次世代を担う若手ファーマ・バイオフォーラム講演要旨集. 2022. 21st
  • 工藤優大, 藤田芽衣, 吉野雄太, 鎌足雄司, 田中義正, 石川岳志, 藤本直浩, 岡田卓哉, 豊岡尚樹, 遠藤智史, et al. オートファゴソーム膜の形成を作用点とする新規オートファジー阻害剤の開発. 日本生化学会大会(Web). 2022. 95th
  • Nagata T, Mashima T, Lee JH, Kamatari YO, Hayashi T, Kinoshita, M, Kuwata K, Katahira M. Structural and functional study of anti-prion aptamers having high activity. The 58th Annual Meeting of the NMR Society of Japan(2019)(Joint Annual Meeting of the 58th NMRJ & the 58th SEST)2019.11.7-9. 2019
  • Tsukasa Mashima, Joon-Hwa Lee, Yuji O. Kamatari, Tomohiko Hayashi, Takashi Nagata, Fumiko Nishikawa, Satoshi Nishikawa, Masahiro Kinoshita, Kazuo Kuwata, Masato Katahira. Development and structural determination of an RNA aptamer that blocks conformational conversion of prion protein. 2019
  • Mashima, M, Joon-Hwa, L, Kamatari, Y. O, Hayashi, T, Nishikawa, F, Nagata, T, Nishikawa, S, Kinoshita, M, Kuwata, K, Katahira, M. Development of RNA Aptamer That Has High Anti-prion Activity and Its Structural Basis. Japan Society of Nucleic Acids Chemistry. 2018
more...
Patents (1):
Lectures and oral presentations  (5):
  • PrionはDoenhill Folder か?
    (2005)
  • 連続光プローブを用いたナノ秒分解レーザー温度ジャンプシステムの開発
    (2005)
  • プリオンの正常立体構造形成過程と異常構造形成過程との共通点
    (2005)
  • Controlling dissociation and association of amyloid protofibrils using high pressure
    (2005)
  • アミロイドプロトフィラメントの解離・会合を圧力により制御する-高圧NMRを用いた研究
    (2005)
Education (1):
  • 1993 - 1996 Kobe University
Professional career (1):
  • 博士(理学) (神戸大学大学院)
Work history (7):
  • 2011/04 - 現在 Gifu University Life Science Research Center Assistant Professor
  • 2005/05 - 2011/03 Gifu University Center for Emerging Infectious Diseases Assistant Professor
  • 2004/04 - 2005/04 RIKEN Genome Science Center Researcher
  • 2001/04 - 2004/03 RIKEN Harima Institute RIKEN Special Postdoctoral Researcher
  • 1997/07 - 2001/03 University of Oxford Oxford Centre for Molecular Sciences Post-doctral Research Fellow
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Association Membership(s) (3):
PROTEIN SCIENCE SOCIETY OF JAPAN ,  The Nuclear Magnetic Resonance Society of Japan ,  THE BIOPHYSICAL SOCIETY OF JAPAN
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