Sato Shinichi

サトウシンイチ | Sato Shinichi

Affiliation and department：
Job title： Associate Professor

Research field (2)： Pharmaceuticals - chemistry and drug development , Biochemistry

Research keywords (5)： Protein Chemical Labeling , Radical Reaction , Photocatalyst , Tyrosine Modification , Antibody Chemical Modification

Research theme for competitive and other funds (14)：

2023 - 2027 Intracellular regulation of photocatalytic proximity labeling for target identification of bioactive molecules
2023 - 2027 Intracellular reaction control of photocatalytic proximity labeling and target identification of bioacitive molecules
2023 - 2025 Comprehensive analysis of binding proteins of symbiotic materials utilizing proximity labeling
2021 - 2024 生物活性分子のプローブ化不要な結合タンパク質網羅的同定
2019 - 2023 Target identification of bioactive molecules based on detection of protein denaturation state

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Papers (79)：

Minoru Ishikawa, Shusuke Tomoshige, Shinichi Sato. Challenges of Aufheben to Promote Druglikeness: Chemical Modification Strategies to Improve Aqueous Solubility and Permeability. Journal of Medicinal Chemistry. 2025
Seiya Ishizawa, Koki Fujimura, Kounosuke Oisaki, Shinichi Sato, Jun Ohata. Catalysis in Chemical Modification of Proteins. ChemCatChem. 2025
Hiroya Abe, Shuri Nakamura, Kentaro Ito, Kosuke Ino, Zhengyi Liu, Shinichi Sato, Kumi Y. Inoue, Hitoshi Shiku. Detection of C-Reactive Protein by Electrochemiluminescence-Based Droplet-Free Digital Immunoassay with Tyramide Signal Amplification. ChemElectroChem. 2025
Seiya Ishizawa, Chiamaka P. Uzoewulu, Yume Iwakura, Anuja Koirala, Shinichi Sato, Jun Ohata. Catalytic Serine Labeling in Nonaqueous, Acidic Media. Chemistry - A European Journal. 2025. 31. 12
Yuki Ban, Yuka Ando, Yuma Terai, Risa Matsumura, Keita Nakane, Shigenori Iwai, Shinichi Sato, Junpei Yamamoto. Profiling of i-motif-binding proteins reveals functional roles of nucleolin in regulation of high-order DNA structures. Nucleic Acids Research. 2024. 52. 22. 13530-13543

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MISC (16)：

佐藤伸一. 酵素によるタンパク質チロシン残基の化学修飾. 酵素工学ニュース. 2024. 92. 10-16
Ahmed Mostafa Abdelhady, Shinichi Sato, Tatsuki Masuzawa, Keishi Deguchi, Keita Nakane, Zhengyi Liu, Kazuki Kuwahara, Fumi Nagatsugi, Takanori Oyoshi, Kazumitsu Onizuka. Photocatalytic proximity labeling for the identification of G-quadruplex DNA-interacting proteins. ChemRxiv. 2024
佐藤伸一. 高反応性化学種による触媒の周辺環境でのタンパク質修飾~チロシン残基修飾研究から発見したヒスチジン残基修飾法~. 電気泳動. 2024. 63. 3
田村朋則, 吉田優, 佐藤伸一, 清中茂樹. ケミカルバイオロジーの冒険(3) 生態を観察するための有機化学生体直行化学. 現代化学. 2024. 6. 639. 42-51
三浦一輝, 對馬理彦, 佐藤伸一, 丹羽達也, 田口英樹, 中村浩之. 細胞内タンパク質間相互作用解析のための光触媒近接タンパク質標識法の開発. 日本ケミカルバイオロジー学会機関誌「ケミカルバイオロジー」. 2024. 17. 1. 6-9

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Books (4)：

Lectures and oral presentations (328)：

タンパク質凝集体部位レベル解析のためのChemical Proteomics
(LiHubワークショップ生命創薬ギルド2025 2025)
Visible-light-induced Proximity Labeling Based on Genetically Encoded Fluorescent Proteins
(The International Chemical Congress of Pacific Basin Societies 2025; Pacifichem 2025 2025)
Development of turn-ON type proximity labeling method for analysis of protein-protein interactions
(The International Chemical Congress of Pacific Basin Societies 2025; Pacifichem 2025 2025)
Probe Development for Protein Aggregates and Site-Specific Mapping via Chemical Proteomics
(2025)
共有結合型タンパク質凝集性化学プローブの開発と抗体劣化の部位レベル解析
(BioMedical Forum 2026 2025)

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Education (3)：

2008 - 2011 東京大学大学院薬学系研究科分子薬学専攻博士後期課程
2006 - 2008 東京大学大学院薬学系研究科分子薬学専攻修士課程
2002 - 2006 Meiji Pharmaceutical University Faculty of Pharmacy Department of Medicinal Chemistry

Professional career (1)：

Work history (7)：

2024/04 - 現在 Tohoku University Frontier Research Institute for Interdisciplinary Sciences Associate Professor
2020/04 - 2024/03 Tohoku University Frontier Research Institute for Interdisciplinary Sciences Assistant Professor
2016/04 - 2020/03 Tokyo Institute of Technology Laboratory for Chemistry and Life Science, Institute of Innovative Research Assitant Professor
2014/02 - 2016/03 Tokyo Institute of Technology Chemical Resources Laboratory Assistant Professor
2012/04 - 2014/01 Gakushuin University Faculty of Science, Department of Chemistry Assistant Professor

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Committee career (4)：

Awards (11)：

2023/04 - 文部科学省令和5年度科学技術分野の文部科学大臣表彰若手科学者賞相互作用解明を実現する触媒的タンパク質化学修飾研究
2020/11 - The Phamaceutical Society of Japan Award for Young Scientists Development of Tyrosine Chemical Modifications and Elucidation of Biological Function
2018/09 - (公社)日本薬学会日本薬学会関東支部奨励賞触媒的タンパク質チロシン残基の化学修飾法の開発と応用
2018/09 - 東京工業大学東京工業大学挑戦的研究賞
2018/06 - 日本ケミカルバイオロジー学会日本ケミカルバイオロジー学会第13回年会ポスター賞溶媒接触度依存的なチロシン残基修飾による抗体の部位選択的機能化

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