Rchr
J-GLOBAL ID：201301009394631203   Update date: Dec. 06, 2024

Inoue Yoshihiro

イノウエ ヨシヒロ | Inoue Yoshihiro
Affiliation and department：
Kyoto Institute of Technology Biomedical Research Center

About Kyoto Institute of Technology Biomedical Research Center


Job title： Professor
Homepage URL  (1)： http://kaken.nii.ac.jp/d/r/90201938.ja.html
Research field  (2)： Cell biology ,  Genetics
Research keywords  (29)： ヒストンmRNA ,  生体老化 ,  DNA酸化損傷 ,  糖尿病モデル生物 ,  造血組織腫瘍モデル ,  小胞体ストレス ,  酸化ストレス ,  抗老化物質 ,  Anti-microbial peptides ,  ショウジョウバエ ,  遺伝子導入動物 ,  アポトーシス ,  シグナル伝達 ,  DNA複製 ,  細胞増殖 ,  劣性変異gl^4 ,  rafの下流因子 ,  パキテン期 ,  放射線感受性(rad-S) ,  生物・生体工学 ,  分化決定 ,  神経症状 ,  P因子挿入突然変異 ,  細胞増殖関連遺伝子 ,  ヒトホモログ ,  MAPキナーゼキナーゼ ,  疾患モデルショウジョウバエ ,  遺伝学 ,  Thrキナ-ゼ
Research theme for competitive and other funds  (30)：
  • 2021 - 2024 Genetic studies on tumor suppression by innate immune system in Drosophila
  • 2020 - 2023 核膜孔複合体のコンポーネント間相互作用とその不和合による生殖的隔離
  • 2017 - 2020 Genetic studies on tumor suppression by innate immune system in Drosophila
  • 2014 - 2018 Genetic Identification of a novel cell cycle checkpoint that monitors damages in mitochondrial dynamics
  • 2011 - 2013 Dynamics of organelles and its regulation by membrane trafficking in Drosophila male meiotic division
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Papers (73)：
  • Juri Kinoshita, Yuriko Kinoshita, Tadashi Nomura, Yoshihiro H. Inoue. Macrophage-like Blood Cells Are Involved in Inter-Tissue Communication to Activate JAK/STAT Signaling, Inducing Antitumor Turandot Proteins in Drosophila Fat Body via the TNF-JNK Pathway. International Journal of Molecular Sciences. 2024. 25. 13110-13129
  • Akihiro Tsuji, Eiji Kotani, Yoshihiro H. Inoue. Sesamin exerts an antioxidative effect by activating the Nrf2 transcription factor in the glial cells of the central nervous system in Drosophila larvae. Antioxidants. 2024. 13. 787
  • Matsuura, Yoshiki, Kana Kaizuka, Yoshihiro H. Inoue. Essential Role of COPII Proteins in Maintaining the Contractile Ring Anchoring to the Plasma Membrane during Cytokinesis in Drosophila Male Meiosis. International Journal of Molecular Sciences. 2024. 25. 8. 4526
  • Yuriko Kinoshita, Naoka Shiratsuchi, Mayo Araki, Yoshihiro H. Inoue. Anti-Tumor Effect of Turandot Proteins Induced via the JAK/STAT Pathway in the mxc hematopoietic tumor mutant in Drosophila. Cells. 2023. 12. 16. 2047
  • Kazuki Takarada, Jyuri Kinoshita, Yoshihiro H. Inoue. Ectopic expression of matrix metalloproteinases and filopodia extension via JNK activation are involved in the invasion of blood tumor cells in Drosophila mxc mutant. Genes to Cells. 2023
ｍore...
MISC (1)：
  • Yusaku Yasuno, Jun-Ichi Kawano, Yoshihiro H. Inoue, Masa-Toshi Yamamoto. Distribution and morphological changes of the Golgi apparatus during Drosophila spermatogenesis. GENES & GENETIC SYSTEMS. 2008. 83. 6. 512-512
Patents (2)：
  • 寿命延長剤、抗老化剤、化粧料及び飲食品組成物
  • 抗老化物質のスクリーニング方法
Lectures and oral presentations  (28)：
  • Mechanism of how antimicrobial peptides, Drosocin and Cecropin A exhibit anti-tumor effect against tumors generated in hematopoietic tissues in Drosophila mxc mutant larvae
    (2024)
  • Involvement of Eiger-JNK signaling and Upd3 in hemocyte-mediated tumor recognition and induction of the Tot proteins having anti-tumor effect in the fat body
    (2024)
  • Sesamin’s effect on age-dependent impairment of protein homeostasis in Drosophila adult muscle : effects on autophagy and ubiquitin-proteasome pathway
    (2024)
  • Anti-tumor Effect of Turandot Proteins Induced via the JAK/STAT Pathway in the mxc Hematopoietic Tumor Mutant in Drosophila
    (The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
  • Sesamin has anti-oxidative stress effects via activation of transcription factor Nrf2 in several larval tissues in Drosophila
    (The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
ｍore...
Education (1)：
  • 1985 - 1989 Waseda University, Graduate school of science and technology
Work history (4)：
  • - 現在 Kyoto Institute of Technology Biomedical Research Center Professor
  • 京都工芸繊維大学 ショウジョウバエ遺伝資源センター 准教授
  • 名古屋大学大学院生命理学研究科 助教
  • 愛知県がんセンター研究所 生物学部 主任研究員
Association Membership(s) (4)：
日本遺伝学会 ,  日本ショウジョウバエ研究会 ,  日本細胞生物学会 ,  日本分子生物学会
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