Rchr
J-GLOBAL ID：201301009936979180
Update date: Nov. 20, 2024
Sagane Yoshimasa
Sagane Yoshimasa
Affiliation and department：
Job title：
Professor
Research field (3)：
Bacteriology
, Structural biochemistry
, Applied biochemistry
Research keywords (5)：
Protein chemistery
, Alternative protein
, Clostridium botulinum
, Botulinum toxin complex
, Molecular Biology
Research theme for competitive and other funds (7)：
- 2022 - 2025 経口毒性が強化された変異型ボツリヌス毒素複合体の機能解析
- 2020 - 2024 iFOODnet: Towards a Norway-Japan Innovative Research & Training Network Driving Next-Generation Food Systems
- 2018 - 2021 Novel "Functional shift" in Cell-Recognition found in Botulinum Neurotoxin Complex
- 2015 - 2018 Molecules involved in intracellular trafficking of botulinum neurotoxin binding protein NTNHA
- 2015 - 2018 Involvement of nontoxic protein in botulinum toxin complex on digestive injury in botulism food poisoning
- 2013 - 2015 Cell-layer transport mechanism of botulinum neurotoxin-binding protein, nontoxic nonhemagglutinin
- 2012 - 2015 Signal transduction of intestinal epithelial cells involved in absorption of botulinum toxin.
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Papers (98)：
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相根義昌, 宮下慎一郎. ボツリヌス毒素の構造と機能解析から導かれる応用可能性. グリーンテクノ情報. 2024. 19. 4. 15-19
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Shin-Ichiro Miyashita, Shura Karatsu, Mako Fujiishi, I Husn Huang, Yuki Nagashima, Tamaki Morobishi, Keita Hosoya, Tsuyoshi Hata, Min Dong, Yoshimasa Sagane. Characterization of Serotype CD Mosaic Botulinum Neurotoxin in Comparison with Serotype C and A. Toxins. 2023
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Karatsu Shura, Miyashita Sin-Ichiro, Hata Tsuyoshi, Huang I Hsun, Hosoya Keita, Sagane Yoshimasa. Variants of hemagglutinin-33 in the serotype C botulinum progenitor toxin complex boost its oral toxicity. 2023. 49. 1. 19-28
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Nakazawa Yozo, Morino Tatsuya, Miyashita Shin-ichiro, Minami Kazuhiro, Sagane Yoshimasa. Development of “Yezo Venison Sausage” with improved texture and bloody taste quality. Nippon Shokuhin Kagaku Kogaku Kaishi. 2023. advpub. 0. 25-31
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Keita Hosoya, Shin-Ichiro Miyashita, Shura Karatsu, I-Hsun Huang, Yoshimasa Sagane. Species-specific gene duplication in Clostridia produces variations of cholesterol-dependent cytolysin with different cytotoxicity. Biochemical and biophysical research communications. 2022. 637. 240-246
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Patents (2)：
Books (5)：
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生食のはなし
朝倉書店 2023 ISBN:9784254431308
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フレーバー・クリエーション
講談社 2014
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Botulinum Toxin Complex: A Delivery Vehicle of Botulinum Neurotoxin Traveling Digestive Tract
InTech 2012
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Structure and function of the Clostridium botulinum serotypes C and D toxin complex. In: Current Topics in Food Science and Technology.
Research Signpost 2005
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初歩からのバイオ実験
三共出版 2002
Lectures and oral presentations (97)：
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長芋パウダーはアイスクリームの安定化剤になるか?
(日本食品保蔵科学会大会講演要旨集 2022)
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抗体医薬を用いた感染制御戦略 ボツリヌス神経毒素を利用した神経細胞への抗体送達によるボツリヌス中毒の治療(Infection control strategies with antibody formulation Delivery of single-domain antibodies into neurons using a detoxified-chimeric toxin)
(日本細菌学雑誌 2022)
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Entry pathways of botulinum toxin complexes into epithelial cells
(日本分子生物学会年会プログラム・要旨集(Web) 2021)
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Oral toxicity of toxin complex produced by Clostridium botulinum type C strain Yoichi in mice
(日本分子生物学会年会プログラム・要旨集(Web) 2021)
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Detoxified botulinum neurotoxin for motor-neuron specific drug delivery
(日本分子生物学会年会プログラム・要旨集(Web) 2021)
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Professional career (1)：
Work history (5)：
- 2018/04/01 - 現在 Tokyo University of Agriculture Faculty of Bio-Industry Department of Food, Aroma and Cosmetic Chemistry Professor
- 2014/04/01 - 2018/03/31 Tokyo University of Agriculture Faculty of Bio-Industry Department of Food and Cosmetic Science Professor
- 2011/09/26 - 2014/03/31 Tokyo University of Agriculture Faculty of Bio-Industry Department of Food and Cosmetic Science Associate Professor
- 2003/04/01 - 2011/09/30 Sars International Centre for Marine Molecular Biology 研究員
- 2001/04/01 - 2003/03/31 Tokyo University of Agriculture Faculty of Bio-Industry -
Committee career (1)：
Association Membership(s) (4)：
食香粧研究会
, 日本細菌学会
, 日本生化学会
, 日本分子生物学会
