Tsumoto Kunichika

ツモトクニチカ | Tsumoto Kunichika

Affiliation and department：
Job title：准教授

Research field (1)： Physiology

Research keywords (9)： Bifurcation Phenomena , Cardiomyocyte , electrophysiology , arrhythmia , nonlinear dynamical system , numerical computation , mathematical modeling , excitation propagation , circadian rhythm

Research theme for competitive and other funds (9)：

2022 - 2025 分岐解析によるヒト心筋細胞モデルデータベース構築と心臓自動能発生機序の統合的解明
2021 - 2023 In silico解析による致死性不整脈トリガーの発生機序解明
2019 - 2022 Theoretical and experimental study of controlling cardiac cell system dynamics using HL-1 mouse cardiomyocytes and a mathematical model
2017 - 2020 Mathematical analysis of arrhythmogenesis for bradycardia
2016 - 2019 The elucidation of mechanisms underlying triggered activity in inheritable lethal arrhythmias: in silico predictions

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Papers (34)：

Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yu-hichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata. Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias. Computer Methods and Programs in Biomedicine. 2023. 240. 107722-107722
Kunichika Tsumoto. Bifurcations and Proarrhythmic Behaviors in Cardiac Electrical Excitations. Biomolecules. 2022. 12. 3. 459-459
Kunichika Tsumoto. Specific decreasing of Na⁺ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome. Scientific Reports. 2020. 10. 1
津元国親, 倉田康孝. 講座:非線形力学系における分岐理論の解析・応用IV; 生体システムにみられる非線形現象:心臓不整脈の発症に関わる心筋細胞応答. システム/制御/情報. 2020. 64. 8. 322-327
Yasutaka Kurata, Kunichika Tsumoto, Kenshi Hayashi, Ichiro Hisatome, Yuhichi Kuda, Mamoru Tanida. Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca2+Release. Frontiers in Physiology. 2020. 10. 1545

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MISC (60)：

Akiko Takahashi, Kunichika Tsumoto, Kazuyuki Aihara, Takuji Kousaka. Numerical method for bifurcation analysis in an impact oscillator with fixed border. 2011 20th European Conference on Circuit Theory and Design (ECCTD). 2011. 257-260
An integration of multi-level electrical activities in the heart: physiome/system biological approach towards in silico cardiology. 2011. 238. 3. 237-243
Yusuke Nishiuchi, Shigeki Tsuji, Kunichika Tsumoto. Expansion of a Software for Analysing Bifurcation Observed in a Non-autonomous System with Square-wave Pulses. IEICE Proceeding Series. 2011. 45. 569-572
高橋明子, 朝長伸吾, 津元国親, 高坂拓司. 固定された境界断面を有する衝突振動系に対する分岐点追跡法. 電子情報通信学会技術研究報告. 2010. 110. 299. 17-20
高橋明子, 朝長伸吾, 津元国親, 高坂拓司. 固定された境界断面を有する衝突振動系における周期解の安定性解析法. 第63回電気関係学会九州支部連合大会講演予稿集. 2010. 624. 624

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Books (12)：

Phase-Resetting Analysis of Gamma-Frequency Synchronization of Cortical Fast-Spiking Interneurons Using Synaptic-like Conductance Injection
2012
Phase response curves in neuroscience : theory, experiment, and analysis
Springer 2011 ISBN:9781493901548
理論生物学 : 生命科学の新しい潮流
共立出版 2011 ISBN:9784320057135
Computational electrophysiology : dynamical systems and bifurcations
Springer 2010 ISBN:9784431538615
臨床医工学スキルアップ講座
大阪大学出版会 2010 ISBN:9784872593631

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Lectures and oral presentations (104)：

第III群抗不整脈薬の催不整脈作用による致死性不整脈の起点としてのEAD誘発撃発活動形成の指向性
(第96回日本薬理学会年会 2023)
心室不整脈の起点としてのEAD誘発撃発活動形成の指向性
(2023年度生理学研究所心血管研究会 2023)
運動ホルモンによる自律神経調節と高脂肪食性肥満への作用
(第32回日本病態生理学会大会 2023)
心室性不整脈発症に関与する撃発活動形成の理論的機序: in silico研究
(第32回日本病態生理学会大会 2023)
ヒト洞結節自動能の非線形力学的発生機序:数理モデル細胞の分岐解析による理論的検証
(第32回日本病態生理学会大会 2023)

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Education (4)：

1999 - 2002 The University of Tokushima Graduate School of Engineering
1997 - 1999 The University of Tokushima Graduate School of Engineering
1995 - 1997 The University of Tokushima Faculty of Engineering Department of Electrical and Electronic Engineering
1990 - 1995 Miyagi National College of Technology Electric Engineering

Professional career (1)：

博士(工学) (徳島大学)

Work history (5)：

2018/08 - 現在 Kanazawa Medical University Faculty of Medicine Associate Professor
2010/10 - 2018/07 Osaka University Graduate School of Medicine Research Associate
2008/06 - 2010/09 Osaka University The Center for Advanced Medical Engineering and Informatics Specially Appointed Research Associate
2004/02 - 2008/05 Japan Science and Technology Agency Aihara Complexity Modelling Project, ERATO Postdoctoral research fellow
2002/04 - 2004/01 Takuma National College of Technology Department of Telecommunication Research assistant

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