Tsumoto Kunichika

ツモトクニチカ | Tsumoto Kunichika

Affiliation and department：
Job title：准教授

Research field (1)： Physiology

Research keywords (9)： Bifurcation Phenomena , Cardiomyocyte , electrophysiology , arrhythmia , nonlinear dynamical system , numerical computation , mathematical modeling , excitation propagation , circadian rhythm

Research theme for competitive and other funds (11)：

2024 - 2027 MMOsの入れ子制御による心臓不整脈の発症予防
2024 - 2027 撃発活動によって惹起された頻脈性心室不整脈の持続機構の解明
2022 - 2025 分岐解析によるヒト心筋細胞モデルデータベース構築と心臓自動能発生機序の統合的解明
2021 - 2024 Mechanisms of triggered activity in lethal arrhythmias: in silico study
2019 - 2022 Theoretical and experimental study of controlling cardiac cell system dynamics using HL-1 mouse cardiomyocytes and a mathematical model

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Papers (46)：

Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yu-hichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata. Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias. Computer Methods and Programs in Biomedicine. 2023. 240. 107722-107722
Kunichika Tsumoto, Yasutaka Kurata. Bifurcations and Proarrhythmic Behaviors in Cardiac Electrical Excitations. Biomolecules. 2022. 12. 3. 459-459
Kunichika Tsumoto, Takashi Ashihara, Narumi Naito, Takao Shimamoto, Akira Amano, Yasutaka Kurata, Yoshihisa Kurachi. Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome. Scientific Reports. 2020. 10. 1
Tao Zhang, Toshishige Shibamoto, Mamoru Tanida, Makoto Taniguchi, Yuhichi Kuda, Wei Yang, Yasutaka Kurata. Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats. PLoS ONE. 2020. 15. 11
津元国親, 倉田康孝. 講座:非線形力学系における分岐理論の解析・応用IV; 生体システムにみられる非線形現象:心臓不整脈の発症に関わる心筋細胞応答. システム/制御/情報. 2020. 64. 8. 322-327

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MISC (10)：

An integration of multi-level electrical activities in the heart: physiome/system biological approach towards in silico cardiology. 2011. 238. 3. 237-243
Kunichika Tsumoto, Takashi Ashihara, Yoshihisa Kurachi. The contribution of sodium channel distributions in the presence of the electric field mechanism to cardiac conduction (Abstracts from the XXth World Congress of the International Society for Heart Research, May 13-16, 2010, Kyoto, Japan). Journal of Molecular and Cellular Cardiology. 2010. 48. 5. S1-S87
村上慎吾, 鈴木慎悟, 倉智嘉久, 津元国親, 上島豊, 野村泰伸. 薬物誘発不整脈発生危険度の予測システム Arrhythmo predictor. 心電図. 2009. 29. Suppl.3. S-394
Yoshinaga Tetsuya, Tsumoto Kunichika, Kawakami Hiroshi. Bifurcation and Global Behavior in Dynamically Coupled Neurons. Proceedings of the IEICE General Conference. 2002. 442-443
Tsumoto K., Yoshinaga T., Kawakami H. Bifurcations in the Hodgkin-Huxley Equation with a Periodic α-function. Proceedings of the IEICE General Conference. 2001. 2001. 67-67

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Books (5)：

Phase response curves in neuroscience : theory, experiment, and analysis
Springer 2011 ISBN:9781493901548
理論生物学 : 生命科学の新しい潮流
共立出版 2011 ISBN:9784320057135
Computational electrophysiology : dynamical systems and bifurcations
Springer 2010 ISBN:9784431538615
臨床医工学スキルアップ講座
大阪大学出版会 2010 ISBN:9784872593631
Chaos in circuits and systems
World Scientific 2002 ISBN:9810249330

Lectures and oral presentations (155)：

第III群抗不整脈薬の催不整脈作用による致死性不整脈の起点としてのEAD誘発撃発活動形成の指向性
(第96回日本薬理学会年会 2023)
心室不整脈の起点としてのEAD誘発撃発活動形成の指向性
(2023年度生理学研究所心血管研究会 2023)
運動ホルモンによる自律神経調節と高脂肪食性肥満への作用
(第32回日本病態生理学会大会 2023)
心室性不整脈発症に関与する撃発活動形成の理論的機序: in silico研究
(第32回日本病態生理学会大会 2023)
ヒト洞結節自動能の非線形力学的発生機序:数理モデル細胞の分岐解析による理論的検証
(第32回日本病態生理学会大会 2023)

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Education (4)：

1999 - 2002 The University of Tokushima Graduate School of Engineering
1997 - 1999 The University of Tokushima Graduate School of Engineering
1995 - 1997 The University of Tokushima Faculty of Engineering Department of Electrical and Electronic Engineering
1990 - 1995 Miyagi National College of Technology Electric Engineering

Professional career (1)：

博士(工学) (徳島大学)

Work history (5)：

2018/08 - 現在 Kanazawa Medical University Faculty of Medicine Associate Professor
2010/10 - 2018/07 Osaka University Graduate School of Medicine Research Associate
2008/06 - 2010/09 Osaka University The Center for Advanced Medical Engineering and Informatics Specially Appointed Research Associate
2004/02 - 2008/05 Japan Science and Technology Agency Aihara Complexity Modelling Project, ERATO Postdoctoral research fellow
2002/04 - 2004/01 Takuma National College of Technology Department of Telecommunication Research assistant

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