Rchr
J-GLOBAL ID：201301012677721447   Update date: Mar. 03, 2025

Tsumoto Kunichika

ツモト クニチカ | Tsumoto Kunichika
Affiliation and department：
金沢医科大学 医学部

About 金沢医科大学 医学部


Job title： 准教授
Research field  (1)： Physiology
Research keywords  (9)： Bifurcation Phenomena ,  Cardiomyocyte ,  electrophysiology ,  arrhythmia ,  nonlinear dynamical system ,  numerical computation ,  mathematical modeling ,  excitation propagation ,  circadian rhythm
Research theme for competitive and other funds  (12)：
  • 2024 - 2027 Understanding the mechanisms of persistent atrial arrhythmias through a multispectral approach using multiple pathological models.
  • 2024 - 2027 MMOsの入れ子制御による心臓不整脈の発症予防
  • 2024 - 2027 撃発活動によって惹起された頻脈性心室不整脈の持続機構の解明
  • 2022 - 2025 分岐解析によるヒト心筋細胞モデルデータベース構築と心臓自動能発生機序の統合的解明
  • 2021 - 2024 Mechanisms of triggered activity in lethal arrhythmias: in silico study
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Papers (36)：
  • Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yuhichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata. Chained occurrences of early afterdepolarizations may create a directional triggered activity to initiate reentrant ventricular tachyarrhythmias. Computer Methods and Programs in Biomedicine. 2025. 261. 108587-108587
  • Yosuke Okamoto, Kunichika Tsumoto. Cardiac Arrhythmia: Molecular Mechanisms and Therapeutic Strategies. International Journal of Molecular Sciences. 2024
  • Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yu-hichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata. Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias. Computer Methods and Programs in Biomedicine. 2023. 240. 107722-107722
  • Kunichika Tsumoto, Yasutaka Kurata. Bifurcations and Proarrhythmic Behaviors in Cardiac Electrical Excitations. Biomolecules. 2022. 12. 3. 459-459
  • Kunichika Tsumoto, Takashi Ashihara, Narumi Naito, Takao Shimamoto, Akira Amano, Yasutaka Kurata, Yoshihisa Kurachi. Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome. Scientific Reports. 2020. 10. 1
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MISC (11)：
  • An integration of multi-level electrical activities in the heart: physiome/system biological approach towards in silico cardiology. 2011. 238. 3. 237-243
  • Yusuke Nishiuchi, Shigeki Tsuji, Kunichika Tsumoto. Expansion of a Software for Analysing Bifurcation Observed in a Non-autonomous System with Square-wave Pulses. IEICE Proceeding Series. 2011. 45. 569-572
  • 村上 慎吾, 鈴木 慎悟, 倉智 嘉久, 津元 国親, 上島 豊, 野村 泰伸. 薬物誘発不整脈発生危険度の予測システム Arrhythmo predictor. 心電図. 2009. 29. Suppl.3. S-394
  • Suzuki S, Ashihara T, Haraguchi R, Tsumoto K, Murakami S, Kurachi Y, Nakazawa K. Reproduction of transmural dispersion of repolarization based on cleft potential hypothesis. Technical Report of the Institute of Electronics, Information and Communication Engineers, ME and Biocybernetics. 2009. 108. 479. 83-88
  • Yoshinaga Tetsuya, Tsumoto Kunichika, Kawakami Hiroshi. Bifurcation and Global Behavior in Dynamically Coupled Neurons. Proceedings of the IEICE General Conference. 2002. 442-443
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Books (8)：
  • Molecular and Computational Modeling of Cardiac Function (Handbook of Modern Biophysics, 7)
    Springer Cham 2025 ISBN:3031737296
  • Cardiac Arrhythmia: Molecular Mechanisms and Therapeutic Strategies
    MDPI 2024 ISBN:9783725829187
  • Molecular pathogenesis of cardiac arrhythmia
    2022 ISBN:9783036556147
  • Phase Response Curves in Neuroscience: Theory, Experiment, and Analysis (Springer Series in Computational Neuroscience, 6)
    Springer 2011 ISBN:1461407389
  • 生命科学の新しい潮流 理論生物学
    共立出版 2011 ISBN:4320057139
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Lectures and oral presentations  (156)：
  • 第III群抗不整脈薬の催不整脈作用による致死性不整脈の起点としてのEAD誘発撃発活動形成の指向性
    (第96回日本薬理学会年会 2023)
  • 心室不整脈の起点としてのEAD誘発撃発活動形成の指向性
    (2023年度 生理学研究所心血管研究会 2023)
  • 運動ホルモンによる自律神経調節と高脂肪食性肥満への作用
    (第32回日本病態生理学会大会 2023)
  • 心室性不整脈発症に関与する撃発活動形成の理論的機序: in silico研究
    (第32回日本病態生理学会大会 2023)
  • ヒト洞結節自動能の非線形力学的発生機序:数理モデル細胞の分岐解析による理論的検証
    (第32回日本病態生理学会大会 2023)
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Education (4)：
  • 1999 - 2002 The University of Tokushima Graduate School of Engineering
  • 1997 - 1999 The University of Tokushima Graduate School of Engineering
  • 1995 - 1997 The University of Tokushima Faculty of Engineering Department of Electrical and Electronic Engineering
  • 1990 - 1995 Miyagi National College of Technology Electric Engineering
Professional career (1)：
  • 博士(工学) (徳島大学)
Work history (5)：
  • 2018/08 - 現在 Kanazawa Medical University Faculty of Medicine Associate Professor
  • 2010/10 - 2018/07 Osaka University Graduate School of Medicine Research Associate
  • 2008/06 - 2010/09 Osaka University The Center for Advanced Medical Engineering and Informatics Specially Appointed Research Associate
  • 2004/02 - 2008/05 Japan Science and Technology Agency Aihara Complexity Modelling Project, ERATO Postdoctoral research fellow
  • 2002/04 - 2004/01 Takuma National College of Technology Department of Telecommunication Research assistant
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