Rchr
J-GLOBAL ID：201301020541201574
Update date: May. 05, 2025
Tsuchihara Katsuya
ツチハラ カツヤ | Tsuchihara Katsuya
Affiliation and department：
Job title：
Director
Other affiliations (2)：
Homepage URL (2)：
https://www.ncc.go.jp/jp/epoc/division/translational_informatics/kashiwa/members/010/index.html
,
https://www.ncc.go.jp/en/epoc/division/translational_informatics/kashiwa/020/index.html
Research field (2)：
Tumor diagnostics and therapeutics
, Tumor biology
Research keywords (2)：
Translational Research
, Oncology
Research theme for competitive and other funds (12)：
- 2017 - 2020 Studies of treatment and carcinogenesis for intrahepatic cholangiocarcinoma by genomic and immunological analysis
- 2016 - 2019 Prediction of radiosensitivity of head and neck cancer using comprehensive genomic analysis
- 2015 - 2018 Evaluation of cellular response to proton radiation with chemotherapic agent in esophageal cancer cell lines
- 2015 - 2018 Identification of reactivation factors for human herpes viruses
- 2015 - 2018 Mutli-Omics single cell analysis
- 2013 - 2016 末梢性T細胞リンパ腫の新規分子標的遺伝子探索 ~初発・再発例の全エクソーム解析~
- 2013 - 2016 Development of a novel diagnostic system using next-generation sequencing for targetable gene alterations in lung cancer
- 2012 - 2015 Comprehensive genomic analysis of small cell lung cancer exploring mechanisms of the proliferation and therapeutic targets
- 2012 - 2015 Exploring therapeutic target kinases by comprehensive genome analysis of lung adenocarcinoma
- 2008 - 2010 Amelioration of tumor susceptibility by lifestyle modification in Snark-knockout mice
- 2006 - 2007 新規AMPK関連キナーゼSNARKの肥満発症への関与
- 1998 - 1999 C型肝炎ウイルス蛋白質による細胞癌化機構の研究
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Papers (167)：
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Shunsuke A Sakai, Ryosuke Nomura, Satoi Nagasawa, SungGi Chi, Ayako Suzuki, Yutaka Suzuki, Mitsuho Imai, Yoshiaki Nakamura, Takayuki Yoshino, Shumpei Ishikawa, et al. SpatialKNifeY (SKNY): Extending from spatial domain to surrounding area to identify microenvironment features with single-cell spatial omics data. PLoS computational biology. 2025. 21. 2. e1012854
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Shunsuke A Sakai, Koichi Saeki, SungGi Chi, Yamato Hamaya, Junyan Du, Masaki Nakamura, Hidehiro Hojo, Takashi Kojima, Yoshiaki Nakamura, Hideaki Bando, et al. Mathematical modeling predicts optimal immune checkpoint inhibitor and radiotherapy combinations and timing of administration. Cancer immunology research. 2024
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Yuma Takano, Jun Suzuki, Kotaro Nomura, Gento Fujii, Junko Zenkoh, Hitomi Kawai, Yuta Kuze, Yukie Kashima, Satoi Nagasawa, Yuka Nakamura, et al. Spatially resolved gene expression profiling of tumor microenvironment reveals key steps of lung adenocarcinoma development. Nature communications. 2024. 15. 1. 10637-10637
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Shinya Hasegawa, Yutaka Shoji, Mamoru Kato, Asmaa Elzawahry, Momoko Nagai, Min Gi, Shugo Suzuki, Hideki Wanibuchi, Sachiyo Mimaki, Katsuya Tsuchihara, et al. Whole Genome Sequencing Analysis of Model Organisms Elucidates the Association Between Environmental Factors and Human Cancer Development. International Journal of Molecular Sciences. 2024
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Kohei Shitara, Kei Muro, Jun Watanabe, Kentaro Yamazaki, Hisatsugu Ohori, Manabu Shiozawa, Atsuo Takashima, Mitsuru Yokota, Akitaka Makiyama, Naoya Akazawa, et al. Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer. Nature medicine. 2024. 30. 3. 730-739
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MISC (271)：
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Takayuki Yoshino, Jun Watanabe, Kohei Shitara, Hirofumi Yasui, Hisatsugu Ohori, Manabu Shiozawa, Kentaro Yamazaki, Eiji Oki, Takeo Sato, Takeshi Naitoh, et al. Panitumumab (PAN) plus mFOLFOX6 versus bevacizumab (BEV) plus mFOLFOX6 as first-line treatment in patients with RAS wild-type (metastatic colorectal cancer (mCRC): Results from the phase 3 PARADIGM trial. JOURNAL OF CLINICAL ONCOLOGY. 2022. 40. 17
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久保 正二, 田中 肖吾, 竹村 茂一, 新川 寛二, 木下 正彦, 佐藤 保則, 三牧 幸代, 土原 一哉, 池田 公史. 職業性胆管癌の病態と治療の進歩. 日本職業・災害医学会会誌. 2021. 69. 臨増. 別33-別33
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大岩 宏聡, 青景 圭樹, 鈴木 絢子, 三牧 幸代, 三好 智裕, 多根 健太, 鮫島 譲司, 土原 一哉, 後藤 功一, 坪井 正博, et al. 壊死を伴うstageI期肺腺癌の臨床病理学的特徴,遺伝子発現および遺伝学的特徴についての検討. 肺癌. 2021. 61. 6. 657-657
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土原 一哉. 【がんゲノム医療を検証する】がん遺伝子パネル検査の光と影. がん分子標的治療. 2021. 19. 1. 15-18
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土原 一哉. 治療抵抗性と不均一性の克服 シングルセルゲノミクスとがん治療の橋渡し. 日本癌学会総会記事. 2021. 80回. [S8-4]
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Education (2)：
- 1996 - 2000 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
- 1987 - 1993 Kanazawa University Faculty of Medicine
Professional career (2)：
- Ph.D. (Tokyo Medical and Dental University)
- M.D. (Kanazawa University)
Work history (12)：
- 2024/07 - 現在 National Cancer Center Exploratory Oncology Research and Clinical Trial Center Director
- 2024/06 - 現在 National Cancer Center Center for Promotion of Translational Research
- 2021/07 - 2024/07 National Cancer Center Center for Promotion of Translational Research Deputy Director
- 2020/04 - 現在 Tokyo University of Science Graduate School of Biomedical Science Visiting Professor
- 2016/04 - 現在 National Cancer Center Exploratory Oncology Research and Clinical Trial Center Chief
- 2014/03 - 現在 The University of Tokyo Graduate School of Frontier Sciences Visiting Professor
- 2022/04 - 2024/05 National Cancer Center Exploratory Oncology Research and Clinical Trial Center Deputy Director
- 2013/07 - 2016/03 National Cancer Center Exploratory Oncology Research and Clinical Trial Center Chief
- 2011/07 - 2014/03 The University of Tokyo Graduate School of Frontier Sciences Visiting Associate Professor
- 2005/04 - 2013/06 National Cancer Center Research Center for Innovative Oncology, Hospital East Head
- 2000/04 - 2005/03 Ontario Cancer Institute Postdoctoral Fellow
- 1998/04 - 2000/03 Japan Society for the Promotion of Science Research Fellow
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