Rchr
J-GLOBAL ID:201301023548024847
Update date: Feb. 14, 2024
Hirate Yoshikazu
ヒラテ ヨシカズ | Hirate Yoshikazu
Affiliation and department:
Job title:
Junior Associate Professor
Homepage URL (2):
http://www.tmd-cea.jp/eam/
,
http://www.tmd-cea.jp/eam/en/
Research field (1):
Developmental biology
Research keywords (3):
Reproductive biology
, Developmental Engineering
, Developmental biology
Research theme for competitive and other funds (9):
- 2018 - 2020 着床メカニズムと母体年齢に関するIn vivo解析
- 2017 - 2019 子宮上皮の再生システムを用いた着床過程の細胞動態の解析
- 2015 - 2017 Sox17へテロ不全マウスを用いた着床メカニズムの解明
- 2011 - 2016 Molecular basis of intercellular communication by Hippo pathway
- 2013 - 2015 AmotとLatsの双方向制御によるHippo経路活性化機構の解明
- 2011 - 2012 Elucidation of cell position-dependent Hippo-pathway regulatorymechanisms in preimplantation embryos
- 胆嚢のマスター遺伝子SOX17の発現制御と胆汁うっ滞性疾患
- 子宮AREG発現を誘導する胚盤胞由来シグナル分子の解明
- 哺乳類の生殖腺の性的2型の維持と破綻の分子基盤の解明
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Papers (47):
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Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, et al. Targeting retrovirus-derived Rtl8a and 8b causes late onset obesity and neurodevelopmental defects. 2023
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Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, et al. SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nature Communications. 2022. 13. 1
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Hirate Yoshikazu, Hayakawa Kana, Nakano Yuki, Kumazawa Shiori, Miura Kento, Kanai Yoshiakira, Kanai-Azuma Masami. Role of SOX17 in crypt formation and regulation of SOX9 and AREG expression at the implantation site(和訳中). Experimental Animals. 2021. 70. Suppl. S61-S61
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Hirate Yoshikazu, Hayakawa Kana, Nakano Yuki, Kumazawa Shiori, Miura Kento, Kanai Yoshiakira, Kanai-Azuma Masami. Early Crypt Formation Defects in the Uterine Epithelia of Sox17 Heterozygous Mice. SEXUAL DEVELOPMENT. 2021. 140. 1-11
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Imura-Kishi Kasane, Uchida Aya, Tsunekawa Naoki, Suzuki Hitomi, Takase Hinako M, Hirate Yoshikazu, Kanai-Azuma Masami, Hiramatsu Ryuji, Kurohmaru Masamichi, Kanai Yoshiakira. Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules. SCIENTIFIC REPORTS. 2021. 11. 1. 1110-1110
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MISC (15):
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UCHIDA Aya, SUZUKI Honoka, TAKASE Hinako M, HIRATE Yoshikazu, HIRAMATSU Ryuji, KUDO Akihiko, AKIMOTO Yoshihiro, KANAI Masami, KANAI Yoshiakira. Mouse rete testis regulates the formation of Sertoli valve epithelia and subsequent spermatogenesis. The Journal of Reproduction and Development Supplement. 2021. 114. OR-40-OR-40
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平手良和, 早川佳那, 中野有紀, 熊澤栞, 三浦健人, 金井克晃, 金井正美. SOX17による着床初期の陰窩形成とSOX9およびAmphiregulinの発現制御. 日本実験動物学会総会講演要旨集(Web). 2021. 68th
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Hirate Y. Technological innovation in mouse developmental engeneering. Biomedical gerontology. 2018. 42. 3. 31-36
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平手良和, 早川佳那, 中野有紀, 上村麻実, 上村麻実, 三浦健人, 金井克晃, 金井正美. 子宮SOX17の着床受容期における下流候補遺伝子の探索. 日本実験動物学会総会講演要旨集. 2018. 65th. 150
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平松竜司, 村田千晴, 三浦健人, 平手良和, 金井正美, 金井克晃. Amh欠損雄マウスを用いたミューラー管遺残症における遺残子宮の比較病態解析. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st. ROMBUNNO.2PW1-12-5 (WEB ONLY)
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Lectures and oral presentations (25):
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頭部外胚葉におけるレンズ誘導におけるMab21l1の機能
(第44回日本分子生物学会年会 2021)
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マウス、ヒト胎盤におけるNrk下流遺伝子群と分娩遅延の関連について
(第44回日本分子生物学会年会 2021)
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SOX17による着床初期の陰窩形成とSOX9およびAmphiregulinの発現制御
(第68回日本実験動物学会総会 2021)
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Mab21l1欠損マウスレンズ前駆細胞の1細胞解析
(第43回日本分子生物学会 2020)
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Comparative study of Nrk gene expression in mice and humans
(The 163rd Annual Meeting of the Japanese Society of Veterinary Medicine 2020)
more...
Professional career (1):
Work history (10):
- 2020/10/01 - 現在 Tokyo Medical and Dental University Institute of Research Research Facility Cluster Center for Experimental Animals Junior Associate Professor
- 2014/04/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Advanced Therapeutic Sciences Experimental Animal Model for Human Disease Junior Associate Professor
- 2017/05/01 - 2020/09/30 Tokyo Medical and Dental University Institute of Research Research Facility Cluster Center for Experimental Animals Junior Associate Professor
- 2017/04/01 - 2017/04/30 Tokyo Medical and Dental University Institute of Research Research Facility Cluster Center for Experimental Animals Junior Associate Professor
- 2014/10/01 - 2017/03/31 Tokyo Medical and Dental University Research and Industry-University Alliance Organization Center for Experimental Animal Junior Associate Professor
- 2014/04/01 - 2014/09/30 Tokyo Medical and Dental University Joint Institutes for Education and Research Center for Experimental Animal Junior Associate Professor
- 2011/04/01 - 2014/03/31 Kumamoto University Institute of Molecular Embryology and Genetics
- 2009/04/01 - 2011/03/31 理化学研究所 発生・再生科学総合研究センター 研究員
- 2006/01/10 - 2009/03/10 Fred Hutchinson Cancer Research Center Postdoctoral Research Fellow
- 2001/04/01 - 2006/01/09 理化学研究所 脳科学総合研究センター 研究員
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Committee career (2):
- 国立大学法人動物実験施設協議会 広報委員
- 国立大学法人動物実験施設協議会 調査委員
Awards (2):
- 2006/06 - Lady Tata Memorial Trust International Award for Research in Leukaemia
- 2004/06 - 第6回ゼブラフィッシュ国際学会 ポスター賞
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