Urasaki Akihiro

ウラサキアキヒロ | Urasaki Akihiro

Affiliation and department：
Job title： Project Associate Professor

Research field (4)： Genomics , Genetics , Molecular biology , Developmental biology

Research keywords (4)：難治性血管病 , 血管・リンパ管形成 , ゼブラフィッシュ , トランスポゾン

Research theme for competitive and other funds (12)：

2023 - 2026 心臓発生期のゲノム網羅的エンハンサーアトラスと心臓内領域特異的遺伝子発現制御機構
2022 - 2025 ALK1シグナルの臓器特異的血管形成における意義と難治性血管疾患の発症メカニズム
2021 - 2024 Downstream genes of signaling pathways implicated in human cardiovascular diseases: in vivo significance and regulatory mechanisms
2020 - 2023 Integrated analysis of pathgenesis of hereditary hemorrhagic telangiectasia
2019 - 2022 胸部大血管および心室筋形成における細胞分化の分子機構

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Papers (23)：

Toru Iwasa, Akihiro Urasaki, Yuki Kakihana, Nami Nagata-Akaho, Yukihiro Harada, Soichi Takeda, Teruhisa Kawamura, Isao Shiraishi, Kenichi Kurosaki, Hiroko Morisaki, et al. Computational and Experimental Analyses for Pathogenicity Prediction of ACVRL1 Missense Variants in Hereditary Hemorrhagic Telangiectasia. Journal of Clinical Medicine. 2023. 12. 15. 5002-5002
Yukihiro Harada, Toru Tanaka, Yuji Arai, Yoshie Isomoto, Atsushi Nakano, Shu Nakao, Akihiro Urasaki, Yusuke Watanabe, Teruhisa Kawamura, Osamu Nakagawa. ETS-dependent enhancers for endothelial-specific expression of serum/glucocorticoid-regulated kinase 1 during mouse embryo development. GENES TO CELLS. 2021
Yumi Kinugasa-Katayama, Yusuke Watanabe, Takashi Hisamitsu, Yuichiro Arima, Norika M. Liu, Ayaka Tomimatsu, Yukihiro Harada, Yuji Arai, Akihiro Urasaki, Teruhisa Kawamura, et al. Tmem100-BAC-EGFP mice to selectively mark and purify embryonic endothelial cells of large caliber arteries in mid-gestational vascular formation. GENESIS. 2021. 59. 4. e23416
Akihiro Urasaki, Seiya Morishita, Kosuke Naka, Minato Uozumi, Kouki Abe, Liguo Huang, Emiko Watase, Osamu Nakagawa, Koichi Kawakami, Takaaki Matsui, et al. Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system. SCIENTIFIC REPORTS. 2019. 9. 1. 12156-12156
Liguo Huang, Akihiro Urasaki, Naoyuki Inagaki. Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain. SCIENTIFIC REPORTS. 2019. 9. 1. 1799-1799

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MISC (9)：

Yusuke Kubo, Akihiro Urasaki, Naoyuki Inagaki. CRMP. 脳科学辞典. 2017. https://bsd.neuroinf.jp/wiki/C
Higashiguchi Yasuna, Katsuta Kazuhiro, Minegishi Takunori, Yonemura Shigenobu, Urasaki Akihiro, Inagaki Naoyuki. Identification of a shootin1 isoform expressed in peripheral tissues. 2016
Baba Kentarou, Urasaki Akihiro, Inagaki Naoyuki. Large gel proteomics-based analyses of the mechanisms for neuronal axon formation and guidance. SEIBUTSU BUTSURI KAGAKU. 2014. 58. 2. 49-52
馬場健太郎, 浦崎明宏, 稲垣直之. Large gel proteomics-based analyses of the mechanisms for neuronal axon formation and guidance. 生物物理化学(Web). 2014. 58. 2. 49-52 (J-STAGE)-52
鈴木良知, 浦崎明宏, 浅見幸夫, 井坂恵一, 川上浩一. Tol2トランスポゾンによる子宮内膜腺癌株(イシカワ株)への効果的な遺伝子導入着床障害不妊症の遺伝子治療に対する有益なDNAベクター(Efficient gene transfer to endometrial adenocarcinoma cell line (Ishikawa) by Tol2 transposable element : a possible DNA vector for gene therapy for implantation failure). 東京医科大学雑誌. 2010. 68. 4. 396-402

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Lectures and oral presentations (34)：

Vascular connection between newly formed intestinal and pre-existing circulatory systems during embryonic development in zebrafish
(The 30th Japanese Vascular Biology and Medicine Organization (JVBMO2022) 2022)
Physiological importance of ALK1 signaling for organotypic vascular formation in zebrafish
(The 5th JCS Council Forum on Basic Cardio Vascular Research (BCVR2022) 2022)
Physiological significance of ALK1 signaling in zebrafish organotypic vascular formation
(The 5th JCS Council Forum on Basic CardioVascular Research (BCVR 2021) 2021)
ACVRL1変異と受容体分子機能の関連解析
(HHT JAPAN 2021(第7回日本HHT研究会) 2021)
Tol2遺伝子導入システムの開発と生体ライブイメージングによる基礎血管研究
(第57回日本小児循環器学会学術集会併催第24回日本小児心血管分子医学研究会 2021)

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Education (1)：

1999 - 2004 The University of Tokyo Graduate School of Agricultural and Life Sciences Department of Biotechnology

Work history (6)：

2024/02 - 現在 Kobe University Project Associate Professor
2023/04 - 2024/01 Kyoto Prefectural University of Medicine Project researcher
2018/07 - 2023/03 National Cerebral and Cardiovascular Center, Research Institute Laboratory Chief
2013 - 2018 Nara Institute of Science and Technology Assistant Professor
2010 - 2013 Hubrecht Institute Postdoctoral Fellow

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Committee career (1)：

2022/09 - 2022/09 The 28th Japanese Medaka and Zebrafish Meeting Organizing Committee

Association Membership(s) (3)：

小型魚類研究会 , 日本分子生物学会 , 日本血管生物医学会

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