Rchr
J-GLOBAL ID：201301038104560227   Update date: Apr. 08, 2024

Mishima Eikan

Mishima Eikan | Mishima Eikan
Affiliation and department：
Helmholtz Zentrum München Institute of Metabolism and Cell Death

About Helmholtz Zentrum München Institute of Metabolism and Cell Death


Job title： Senior scientist
Other affiliations (1)：
Research field  (3)： Molecular biology ,  Nephrology ,  Metabolism and endocrinology
Research keywords  (10)： Ferroptosis ,  Lipie peroxidation ,  Cell death ,  vitamin K ,  Oxidative stress ,  Metabolome ,  Microbiota ,  Nephrology ,  Hypertension ,  Endocrinology
Research theme for competitive and other funds  (17)：
  • 2020 - 2023 ながはまコホートおよび佐渡コホートのゲノム情報解析による、尿酸値関連変異の探索
  • 2021 - 2023 Lipid radicals in regulation of ferroptosis
  • 2023 - 生命進化における抗フェロトーシスビタミンとしてのビタミンKの役割と治療応用
  • 2016 - 2022 応用酵素協会 成人病の病因・病態の解明に関する研究助成
  • 2018 - 2021 Gut-renal axis: microbiota and chronic kidney disease
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Papers (136)：
  • Raphaël Rodriguez, Tatiana Cañeque, Leeroy Baron, Sebastian Müller, Alanis Carmona, Ludovic Colombeau, Antoine Versini, Marie Sabatier, Julio Sampaio, Eikan Mishima, et al. Activation of lysosomal iron triggers ferroptosis in cancer. 2024
  • Yusuke Hirata, Eikan Mishima. Membrane Dynamics and Cation Handling in Ferroptosis. Physiology. 2024. 39. 2. 73-87
  • Toshitaka Nakamura, Junya Ito, André Santos Dias Mourão, Adam Wahida, Kiyotaka Nakagawa, Eikan Mishima, Marcus Conrad. A tangible method to assess native ferroptosis suppressor activity. Cell reports methods. 2024. 100710-100710
  • Toshitaka Nakamura, Eikan Mishima, Naoya Yamada, André Santos Dias Mourão, Dietrich Trümbach, Sebastian Doll, Jonas Wanninger, Elena Lytton, Peter Sennhenn, Thamara Nishida Xavier da Silva, et al. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nature Structural & Molecular Biology. 2023
  • Kimio Watanabe, Emiko Sato, Eikan Mishima, Shinobu Moriya, Takuma Sakabe, Atsuya Sato, Momoko Fujiwara, Takuya Fujimaru, Yugo Ito, Fumika Taki, et al. Changes in Metabolomic Profiles Induced by Switching from an Erythropoiesis-Stimulating Agent to a Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor in Hemodialysis Patients: A Pilot Study. International Journal of Molecular Sciences. 2023
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MISC (72)：
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Patents (2)：
  • フェロトーシス抑制剤
  • フェロトーシス抑制薬の同定
Professional career (1)：
  • 医学博士 (東北大学)
Work history (14)：
  • 2023/03 - 現在 ヘルムホルツセンター・ミュンヘン 上級研究員
  • 2020/10 - 現在 Tohoku University of Medicine Division of Nephrology, Rheumatology and Endocrinology Researcher
  • 2020/10 - 2023/02 Helmholtz Zentrum München Institute of Metabolism and Cell Death Guest scientist
  • 2019/04 - 2020/09 Tohoku University Graduate School of Medicine University Hospital Nephrology, Endocrinology and Vascular Medicine Associate professor / lecturer
  • 2016/02 - 2019/03 Tohoku University Graduate School of Medicine Division of Nephrology, Endocrinology and Vascular Medicine Assistant Professor
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Committee career (10)：
  • 2023 - 現在 日本高血圧学会 U-45委員会
  • 2020 - 現在 Editorial borad member, BMC Nephrology
  • 2020 - 現在 日本高血圧学会 国際交流委員会
  • 2019 - 現在 日本腎臓学会 広報委員会
  • 2018 - 現在 日本腎臓学会 JSN Next Frontiers 2028委員会
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Awards (32)：
  • 2023 - 日本ビタミン学会 奨励賞
  • 2023 - 安藤百福賞 発明発見奨励賞
  • 2023 - JSN Oshima Award
  • 2022 - Helmholtz Munich Best Paper Award 2022
  • 2021 - 第9回臨床高血圧フォーラム 優秀演題賞
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Association Membership(s) (9)：
THE JAPANESE SOCIETY FOR DIALYSIS THERAPY ,  JAPAN PRIMARY CARE ASSOCIATION ,  JAPANESE SOCIETY OF GOUT AND NUCLEIC ACID METABOLISM ,  日本心血管内分泌代謝学会 ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  The Japan Endocrine Society ,  The Japanese Society of Hypertension ,  JAPANESE SOCIETY OF NEPHROLOGY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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