2010 - 2011 Toward the understanding of the switching mechanism between DNA checkpo i nt and repa i r mach i neries at DNA damage s i tes.
2005 - 2009 Molecular mechanism of microbial DNA partitioning : structure and function
2007 - 2008 A construction of real-time detection probe for intracellular DNA checkpoint activation
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Papers (41)：
Masae Ikura, Kanji Furuya, Yasunori Horikoshi, Satoshi Tashiro, Takuma Shiraki, Tsuyoshi Ikura. Acetylation-Dependent Histone H2AX Exchange Suppresses Pathological Senescence via MDC1 Degradation. Molecular and Cellular Biology. 2026. 46. 297-317
Masae Ikura, Tsuyoshi Ikura, Kanji Furuya. Machine Learning Extracts Radiation Resistant-Specific EdU Fluorescence Pattern in Cancer Cells. Genes to cells : devoted to molecular & cellular mechanisms. 2025. 30. 5. e70050
Shoko Mizutani, Kanji Furuya, Ayumi Mure, Yuuki Takahashi, Akihiro Mori, Nozomu Sakurai, Takuto Suito, Kohjiro Nagao, Masato Umeda, Kaori Watanabe, et al. Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males. EMBO Reports. 2025
Masae Ikura, Takuma Shiraki, Tsuyoshi Ikura, Kanji Furuya. Autophagy promotes the acquisition of genotoxic resistance in cancer cells in a paracrine manner via upregulation of PLK1-RAD9A axis. The Journal Of Biochemistry. 2025
Kanji Furuya, Masae Ikura, Tsuyoshi Ikura. Machine learning extracts oncogenic-specific γ-H2AX foci formation pattern upon genotoxic stress. Genes to Cells. 2023
Heterogeneity and cooperativity within cancer cell populations during the radioresistance acquisition
(97th Annual meeting of Japanese Biochemical Society 2024)
Challenges in Mathematical Approaches to Unravel the Mechanisms Responsible for Radiation Resistance in Cancer cells
(2024)
Histone Sensing:A New Insight for Aging Research
(The 67th Annual Meeting of the Japanese Radiation Research Society 2024)
Growth, senescence and death transition in fission yeast
(11th International Pombe Meeting)
