Rchr
J-GLOBAL ID：201301047811390973   Update date: Sep. 10, 2024

Kato Taisuke

カトウ タイスケ | Kato Taisuke
Affiliation and department：
Niigata University Brain Research Institute

About Niigata University Brain Research Institute


Job title： Associate professor
Research field  (2)： Molecular biology ,  Neuroscience - general
Research keywords  (6)： Polyglutamine diseases ,  Genome editing ,  Small vessel disease ,  包括脳ネットワーク ,  amyotrophic lateral sclerosis ,  CARASIL
Research theme for competitive and other funds  (9)：
  • 2022 - 2025 脳小血管の細胞外基質の摂動を起こす細胞群の同定と、その制御機構の解読
  • 2022 - 2025 脳小血管線維化促進細胞の同定による脳小血管老化の解明
  • 2021 - 2024 細胞老化から解く、真のTDP-43プロテイノパチー分子機構への挑戦
  • 2019 - 2022 Approach to neurodegenerative disorders by elucidation of the excretion pathway of the brain.
  • 2018 - 2021 Elucidation of the mechanism of gain-of-toxic function by abnormal subcellular localization of cerebral small vessel disease-related mutant TREX1
Show all
Papers (52)：
  • Samuel D. Chauvin, Shoichiro Ando, Joe A. Holley, Atsushi Sugie, Fang R. Zhao, Subhajit Poddar, Rei Kato, Cathrine A. Miner, Yohei Nitta, Siddharth R. Krishnamurthy, et al. Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans. Nature Communications. 2024. 15. 1
  • 坪口 晋太朗, 中村 由香, 石原 智彦, 加藤 泰介, 佐藤 時春, 小山 哲秀, 森 秀樹, 小池 佑佳, 小野寺 理, 上野 将紀. TDP-43は運動回路の変性を誘導するために異なって伝播する(TDP-43 differentially propagates to induce degeneration in the motor circuit). Dementia Japan. 2023. 37. 4. 680-680
  • Shintaro Tsuboguchi, Yuka Nakamura, Tomohiko Ishihara, Taisuke Kato, Tokiharu Sato, Akihide Koyama, Hideki Mori, Yuka Koike, Osamu Onodera, Masaki Ueno. TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models. Acta neuropathologica. 2023
  • Masahiro Uemura, Sho Kitahara, Taisuke Kato, Hiroaki Nozaki, Shoichiro Ando, Tomohiko Ishihara, Osamu Onodera. Inappropriate interpretation of non-pathogenic HTRA1 variant as pathogenic. Annals of clinical and translational neurology. 2023. 10. 7. 1261-1262
  • Yutaka Otsu, Masahiro Hatakeyama, Takeshi Kanayama, Natsuki Akiyama, Itaru Ninomiya, Kaoru Omae, Taisuke Kato, Osamu Onodera, Masanori Fukushima, Takayoshi Shimohata, et al. Oxygen-Glucose Deprived Peripheral Blood Mononuclear Cells Protect Against Ischemic Stroke. Neurotherapeutics. 2023
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MISC (39)：
  • 坪口晋太朗, 中村由香, 石原智彦, 加藤泰介, 佐藤時春, 小山哲秀, 森秀樹, 小池佑佳, 小野寺理, 小野寺理, et al. TDP-43 differentially propagates to induce degeneration in the motor circuit. Dementia Japan. 2023. 37. 4
  • 森秀樹, 坪口晋太朗, 佐藤時春, 中村由香, 加藤泰介, 須貝章弘, 小野寺理, 上野将紀. TDP-43変異型により異なる病態進展特性の解析. Dementia Japan. 2023. 37. 4
  • 加藤泰介, 眞鍋理一郎, 五十嵐博中, 亀谷富由樹, 齊藤聡, 畠野雄也, 安藤昭一朗, 福永雅喜, 佐藤俊哉, 齋藤理恵, et al. 遺伝性脳小血管病モデルから見えてきたmatrisomeの破綻と治療法の展望. Dementia Japan. 2022. 36. 4
  • 加藤泰介, 眞鍋理一郎, 五十嵐博中, 亀谷富由樹, 齊藤聡, 畠野雄也, 安藤昭一朗, 福永雅喜, 佐藤俊哉, 齋藤理恵, et al. Matrisomeの擾乱から見た脳小血管病の分子病態と治療法への展望. Dementia Japan. 2022. 36. 4
  • TSUBOGUCHI Shintaro, NAKAMURA Yuka, ISHIHARA Tomohiko, KATO Taisuke, KOYAMA Akihide, SATO Tokiharu, YOSHIDA Yutaka, UENO Masaki, ONODERA Osamu. Spreading of TDP-43 via direct corticospinal connections in mouse models. 日本神経学会学術大会プログラム・抄録集. 2020. 61st
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Lectures and oral presentations  (4)：
  • Gene therapy for DRPLA model mice by AAV-delivered CRISPR / Cas9
    (Genome Engineering: From Mechanisms to Therapies, Keystone Symposia Conference 2019)
  • Therapeutic strategy based on genome editing by CRISPR/Cas9 for polyglutamine disease using DRPLA model
    (Advances in Neurodegenerative Disease Research and Therapy. Keystone Symposia Conference. 2018)
  • Serine protease HTRA1 deficiency induces arteriopathy in cerebral small vessels.
    (2017)
  • Serine protease HTRA1 deficiency induces arteriopathy in cerebral small vessels.
    (Neuroscience2017 2017)
Education (3)：
  • 2006 - 2010 Niigata University Graduate School of Medical and Dental Sciences
  • 2004 - 2006 Niigata University Graduate School of Medical and Dental Sciences
  • 2000 - 2004 Niigata University Faculty of Agriculture Department of Applied Biological Chemistry
Professional career (1)：
  • 医学博士 (Ph.D.) (新潟大学)
Work history (3)：
  • 2022/04 - 現在 新潟大学脳研究所 分子神経疾患資源解析学分野 准教授
  • 2017/04 - 2022/03 Niigata University Brain Research Institute
  • 2013/10 - 2016/03 Niigata University Brain Research Institute
Awards (1)：
  • 2014 - 包括型脳科学研究推進支援ネットワーク 夏のワークショップ若手優秀発表賞受賞 筋萎縮性側索硬化症運動神経細胞におけるTDP-43 mRNAの細胞内局在解析
Association Membership(s) (3)：
THE JAPAN NEUROSCIENCE SOCIETY ,  Japanese Society for Neurochemistry ,  Society for Neuroscience
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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