Rchr
J-GLOBAL ID:201301060883810094
Update date: Nov. 13, 2025
Matsuda Akira
マツダ アキラ | Matsuda Akira
Affiliation and department:
Job title:
Associate Proffessor
Homepage URL (1):
http://kaken.nii.ac.jp/d/r/00312348.ja.html
Research field (2):
Ophthalmology
, Allergies and connective tissue disease
Research keywords (19):
wound healing
, TSLP
, ILC2
, atopic glaucoma
, atopic cataract
, vernal keratoconjunctivitis
, atopic keratoconjunctivitis
, RNA-seq
, mast cell
, periostin
, IL-33
, アトピー性皮膚炎
, エピジェネティクス
, 緑内障
, ステロイド
, ノックアウトマウス
, テネイシン
, 遺伝子多型
, ステロイド緑内障
Research theme for competitive and other funds (28):
- 2025 - 2028 アトピー性角結膜炎の病態とIL-25シグナル、シャルコー・ライデン結晶の役割
- 2022 - 2025 緑内障濾過手術におけるペリオスチンの役割
- 2021 - 2024 慢性重症アレルギー性角結膜炎におけるIL-33陽性活性化線維芽細胞の機能解析
- 2019 - 2022 Pathophysiology and genetic predispositions of severe chronic allergic keratoconjunctivitis
- 2016 - 2019 Lymphatic vessels in glaucoma filtration surgery
- 2016 - 2019 Regulation of leukotriene B4 receptor2(BLT2) accelerates corneal wound by NSAIDs
- 2016 - 2018 The role of ILC2 in allergic conjunctivitis
- 2014 - 2017 Regulation of tissue fibrosis and natural helper cells in ocular atopy
- 2013 - 2015 Investigation for the causative genes for atopic cataracts
- 2013 - 2015 The roles of Alarmin for the pathophysiology of Atopic Retinal Detachment
- 2012 - 2015 The effect of Mast cell Tryptase to the Expression of Eotaxin-1/CCL11, Eotaxin-2/CCL24 and Eotaxin-3/CCL26 by Conjunctival Fibroblasts.
- 2012 - 2014 Atopic keratoconjunctivitis and natural helper cell
- 2012 - 2014 アトピー緑内障の病態解析
- 2012 - 2014 カスタムチップを用いた既知の原発開放隅角緑内障関連遺伝子に対する候補遺伝子解析
- 2009 - 2011 Investigation of epigenetic factors in the pathogenesis of glucocorticoid-induced glaucoma
- 2009 - 2011 The elucidation of the mechanism regulating the epithelial tight-junction by the TACSTD2 gene
- 2009 - 2011 Evaluation of oxidative stress on trabecular meshwork cells and lens or iris epithelial cells in pseudoexfoliation glaucoma patients
- 2009 - 2011 IFN-γPAI-1 signals in ocular complications of atopic diseases
- 2008 - 2010 The expression of high affinity IgE receptor β-chain in human mast cells and basophils, and its roles
- 2008 - 2010 The development of basic technologies for the cellular therapy of corneal epithelial cells by the regulation of cellular senescence and epigenetic changes
- 2007 - 2008 Involvement of functional RNA and epigenetic regulation in the specific function of corneal epithelium
- 2007 - 2008 Regeneration of lacrimal grand by the induction of highly-ordered acinus branching
- 2007 - 2008 アトピー眼症におけるビタミンD3およびTSLP分子の機能解析
- 2006 - 2007 The roles of tenascin-C for corneal epithelial stem cell niche
- 2000 - 2001 ハイリスク角膜移植における拒絶反応阻止のための研究
- 1999 - 1999 実験的角膜移植の拒絶反応における細胞外基質の役割に関する研究
- 1997 - 1999 Expression and significance of MIF in the ocular tissue.
- 進行中および終了した研究課題
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Papers (133):
-
Chihiro Koiwa, Yusuke Hayashi, Satoko Asaoka, Kohei Kuroda, Yosuke Asada, Toshimitsu Kasuga, Satoshi Iwamoto, Toshiaki Hirakata, Rio Honda, Hanako Obazawa, et al. Midterm outcomes of Ahmed glaucoma valve implantation and trabeculectomy in exfoliative glaucoma. Japanese journal of ophthalmology. 2025. 69. 6. 938-946
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Satoshi Nunomura, Yasuhiro Nanri, Yuko Honda, Hironobu Takedomi, Takashi Okada, Xin Tun, Simon J Conway, Isao Kitajima, Nobuyuki Ebihara, Akira Matsuda, et al. Periostin promotes inflammation and neovascularization in atopic keratoconjunctivitis. The Journal of allergy and clinical immunology. 2025
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Kentaro Iwasaki, Sachi Kojima, Ryotaro Wajima, Akira Matsuda, Koki Yoshida, Aika Tsutsui, Michihiro Kono, Miho Nozaki, Koji Namiguchi, Keisuke Nitta, et al. Surgical Outcomes of Baerveldt Glaucoma Implant Versus Ahmed Glaucoma Valve in Neovascular Glaucoma: A Retrospective Multicenter Study. Advances in therapy. 2025. 42. 4. 1745-1759
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Jun Shoji, Yousuke Asada, Rumi Adachi, Noriko Inada, Eiichi Uchio, Yoko Kataoka, Norito Katoh, Tatsuma Kishimoto, Eisuke Shimizu, Tamaki Sumi, et al. Questionnaire survey among ophthalmic allergists on dupilumab-associated ocular surface disease in Japan. Allergology international : official journal of the Japanese Society of Allergology. 2024. 74. 2. 333-335
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Miki Onoue, Akiko Saga, Keisuke Adachi, Yosuke Asada, Toshiaki Hirakata, Satoshi Iwamoto, Shigeharu Ueki, Nobuyuki Ebihara, Akira Matsuda. Eosinophil extracellular trap formation in the giant papillae of atopic keratoconjunctivitis and vernal keratoconjunctivitis. Allergology international : official journal of the Japanese Society of Allergology. 2023
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MISC (103):
Lectures and oral presentations (96):
-
レゾルビンによるマウスアレルギー性結膜炎の制御
(日本眼科学会雑誌 2018)
-
涙腺除去パパイン誘発アレルギー性結膜炎におけるILC2の役割
(日本眼科学会雑誌 2018)
-
マウス濾過手術後の遺伝子発現の変化
(日本眼科学会雑誌 2018)
-
動物モデル 気道炎症 抗原のプロテアーゼ活性と機械的な皮膚バリア破壊は相乗的に経皮感作を促進する
(アレルギー 2017)
-
マウスアレルギー性結膜炎モデルにおけるレゾルビンの効果
(日本眼科学会雑誌 2017)
more...
Education (2):
- 1995 - 1999 Hokkaido University Graduate School of Medicine
- 1985 - 1991 Hokkaido University School of Medicine
Professional career (1):
Work history (5):
- 2024/01 - 現在 Nihon University School of Medicine Department of Medicine Associate Proffessor
- 2009/04 - 2023/12 Juntendo University
- 2005/09 - 2009/03 Kyoto Prefectural University of Medicine
- 2003/04 - 2005/08 理化学研究所 研究員
- 1999/04 - 2003/03 Hokkaido University Graduate School of Medicine
Association Membership(s) (7):
ARVO
, American academy of Ophthalmology
, JAPAN GLAUCOMA SOCIETY
, JAPAN CORNEA SOCIETY
, JAPANESE SOCIETY OF ALLERGOLOGY
, JAPANESE OPHTHALMOLOGICAL SOCIETY
, 日本眼科アレルギー学会
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