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J-GLOBAL ID:201301068714571138   Update date: Jul. 04, 2024

Urano Yasuomi

ウラノ ヤスオミ | Urano Yasuomi
Affiliation and department:
Job title: 准教授
Research field  (1): Cell biology
Research keywords  (9): 細胞死 ,  神経科学 ,  脂質 ,  コレステロール ,  痴呆 ,  脂質代謝 ,  アルツハイマー病 ,  細胞内輸送 ,  oxysterol
Research theme for competitive and other funds  (14):
  • 2024 - 2027 The regulation mechanism of oxidation and hypersulfidation in increase of effects of exercise for diabetes prevention
  • 2023 - 2026 食品性抗酸化物質によるオキシステロール誘導性細胞死抑制機構の解明と応用
  • 2021 - 2022 コレステロール酸化物による細胞死誘導機構解明に向けた基盤研究とがん治療への応用
  • 2019 - 2022 Basic research on the development of therapeutic agents for Alzheimer's disease using Acyl-CoA:cholesterol acyltransferase inhibitor
  • 2022 - ビタミンEとコエンザイムQ10によるオキシステロール誘導性細胞死抑制機構の解明
Show all
Papers (41):
  • Yasuomi Urano, Noriko Noguchi. Enzymatically Formed Oxysterols and Cell Death. Advances in experimental medicine and biology. 2024. 1440. 193-211
  • Ren Chiba, Yasuomi Urano, Noriko Noguchi. α-Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of endoplasmic reticulum membrane disruption. Steroids. 2023. 189. 109136-109136
  • Yusuke Nakatani, Naofumi Shimokawa, Yasuomi Urano, Noriko Noguchi, Masahiro Takagi. Suppression of Amyloid-β Adsorption on Endoplasmic Reticulum Stress-Mimicking Membranes by α-Tocopherol and α-Tocotrienol. The Journal of Physical Chemistry Letters. 2022. 11955-11960
  • Yasuomi Urano, Shoya Osaki, Ren Chiba, Noriko Noguchi. Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism. Cell Death Discovery. 2022
  • Biplab Kumar Dash, Yasuomi Urano, Yoshiro Saito, Noriko Noguchi. Redox-sensitive DJ-1 protein: an insight into physiological roles, secretion, and therapeutic target. Redox Experimental Medicine. 2022
more...
MISC (13):
Patents (11):
Books (1):
  • 24S-OHC誘導性細胞死に対するビタミンE類の添加効果
    ビタミンEの進歩ビタミンE研究会 2012
Lectures and oral presentations  (43):
  • 25-Hydroxycholesterol induces ferroptosis via downregulation of mevalonate pathway in Schwann cells
    (10th ENOR SYMPOSIUM 2021)
  • 脳特異的オキシステロール24S-hydroxycholesterolによる神経細胞死誘導における小胞体の関与
    (第27回日本Cell death学会学術集会 2018)
  • 24S-ヒドロキシコレステロールが誘導する神経細胞死に対するビタミンEの抑制機構の解析
    (第29回ビタミンE研究会 2018)
  • 24S-Hydroxycholesterol誘導性神経細胞死に対するビタミンEの効果
    (ConBio2017 2017)
  • 一酸化炭素放出分子を用いた一酸化炭素によるAβ産生への影響の解析
    (ConBio2017 2017)
more...
Education (3):
  • - 2004 The University of Tokyo
  • - 2000 Chiba University
  • - 1998 Chiba University Faculty of Pharmaceutical Sciences
Professional career (2):
  • 博士(工学) (東京大学)
  • 修士(薬学) (千葉大学)
Work history (5):
  • 2024 - 現在 Doshisha University Faculty of Life and Medical Sciences
  • 2018 - 2023 Doshisha University Faculty of Life and Medical Sciences
  • 2009 - 2018 Doshisha University Faculty of Life and Medical Sciences
  • 2005 - 2009 Dartmouth Medical School Research Associate
  • 2004 - 2005 The University of Tokyo Research Center for Advanced Science and Technology
Association Membership(s) (5):
日本cell death学会 ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  日本脂質生化学会 ,  The American Society for Biochemistry and Molecular Biology
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