Research field (2)：
Statistical science
, Pharmacology
Research keywords (6)：
Epidemiology
, Clinical Research
, Meta-analysis
, BIOSTATISTICS
, 臨床試験
, 医薬生物・ゲノム統計解析
Research theme for competitive and other funds (7)：
2021 - 2024 Re-evaluation of evidence reflecting patient's value with individual patient based meta-analysis
2019 - 2022 Development and application of biostatistical methods for longitudinal life course epidemiology data
2015 - 2019 Individual-patient-based data meta-analysis of randomized trials in gastric cancer
2013 - 2017 Association of obesity indexes with metaboric risk factors
2013 - 2017 Re-evaluation of clinical effectiveness of four neuraminidase inhibitors against influenza viruses using molecular biology and epidemiological studies
2009 - 2010 Evaluation of validity of a surrogate variable based on the causal effect
2008 - 2010 Efficient Approaches of Case Registration and Data management in Clinical Trials
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Papers (321)：
Taikei Akiyama, Hideo Fukuhara, Yasuhiro Hagiwara, Satoshi Fukata, Yutaka Matsuyama, Keiji Inoue, Koji Oba. Cost-effectiveness analysis of transurethral resection of bladder tumor with photodynamic diagnosis with 5-aminolevulinic acid hydrochloride for non-muscle invasive bladder cancer. Photodiagnosis and photodynamic therapy. 2026. 105495-105495
Jean-Christophe Chiem, Hatem Alharazin, Everardo D Saad, Koji Oba, Masaru Muto, Hisakazu Yamagishi, Junichi Sakamoto, Takaki Yoshikawa, Marc Buyse. Benefit-risk balance of S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC). The oncologist. 2026. 31. 4
Hidetaka Kawamura, Michitaka Honda, Yujiro Nakayama, Koji Oba, Masaru Muto, Toru Aoyama, Mitsuro Kanda, Hiromichi Maeda, Shuhei Mayanagi, Kosuke Kashiwabara, et al. Adverse events of postoperative adjuvant chemotherapy predict survival outcomes in locally advanced colorectal cancer: a pooled analysis of Japanese clinical trials. British journal of cancer. 2025. 133. 11. 1660-1667
Shohei Matsumoto, Takahiro Tsuboyama, Hiromitsu Onishi, Koki Kaketaka, Tetsuya Wakayama, Xinzeng Wang, Atsushi Nakamoto, Takashi Ota, Hideyuki Fukui, Toru Honda, et al. DWI of the rectum with deep learning reconstruction: comparison of PROPELLER, reduced FOV, and conventional DWI. Abdominal radiology (New York). 2025. 50. 11. 5079-5089
Nobuaki Hoshino, Mitsuro Kanda, Koji Oba, Toru Aoyama, Michitaka Honda, Kosuke Kashiwabara, Hiromichi Maeda, Shuhei Mayanagi, Masaru Muto, Kenji Tanaka, et al. Efficacy and safety of oral 5-FU-based adjuvant chemotherapy for geriatric patients with colorectal cancer: Integrated analysis of seven clinical trials conducted at the Japanese Foundation for Multidisciplinary Treatment of Cancer. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2025. 27. 11. e70317
Larbi Aluariachy, Isao Yokota, Kentaro Sakamaki, Koji Oba. Dynamic Prediction of Survival Outcomes Using Longitudinal Biomarkers. Japanese Journal of Biometrics. 2024. 45. 2. 189-214
Multicenter phase Ib/II study of biweekly trifluridine/tipiracil with bevacizumab combination for patients with metastatic colorectal cancer refractory to standard therapies (BITS study).
(JOURNAL OF CLINICAL ONCOLOGY 2019)
Sustained Clinical Remission after Discontinuation of Infliximab with a Raising Dose Strategy in Patients with Rheumatoid Arthritis (RRRR study): A Randomized Controlled Trial
(ARTHRITIS & RHEUMATOLOGY 2018)
SAPPHIRE: A randomized phase II study of mFOLFOX6+panitumumab versus 5-FU/LV + panitumumab after 6 cycles of frontline mFOLFOX6+panitumumab in patients with colorectal cancer.
(JOURNAL OF CLINICAL ONCOLOGY 2018)
Trial in progress: A phase II study of second-line FOLFIRI plus panitumumab after first-line FOLFOX plus panitumumab for RAS wild-type colorectal cancer with evaluation of circulating tumor DNA.
(JOURNAL OF CLINICAL ONCOLOGY 2018)
Clinical impact of postoperative surgical complications on the colorectal cancer survival and recurrence: Analyses of pooled individual patients' data from three large phase III randomized trials
(ANNALS OF ONCOLOGY 2017)
