Rchr
J-GLOBAL ID：201301076150605870   Update date: Nov. 13, 2024

NAKASHIMA AYUMU

ナカシマ アユム | NAKASHIMA AYUMU
Affiliation and department：
University of Yamanashi Graduate Faculty of Interdisciplinary Research Faculty of Medicine

About University of Yamanashi Graduate Faculty of Interdisciplinary Research Faculty of Medicine


Job title： Professor
Homepage URL  (1)： https://www.hosp.yamanashi.ac.jp/departments/1442/
Research field  (1)： Nephrology
Research keywords  (1)： Nephrology; Dialysis therapy; Regenerative Medicine; Hypertension; Chronobiology; Atherosclerosis; CKD-MBD; Mesenchymal Stem Cells; Fibrosis; Inflammation
Research theme for competitive and other funds  (25)：
  • 2022 - 2027 elucidation of enos regulation mechanism by a novel resistin-like molecule beta, and Its relationship to atherosclerosis
  • 2023 - 2026 間葉系幹細胞のEpigenetic制御によるNa輸送体変化を介した降圧効果
  • 2023 - 2026 Suppression of renal injury by extracellular vesicles from mesenchymal stem cells
  • 2022 - 2025 内皮型NO合成酵素制御および血管内皮機能調整における時計遺伝子DEC1の役割
  • 2021 - 2025 脂肪由来間葉系幹細胞の分化ポテンシャル予知マーカーシステムの開発
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Papers (190)：
  • Kisho Miyasako, Ayumu Nakashima, Naoki Ishiuchi, Yoshiki Tanaka, Keisuke Morimoto, Kensuke Sasaki, Shogo Nagamatsu, Go Matsuda, Takao Masaki. Impact of immunosuppressive drugs on efficacy of mesenchymal stem cell therapy for suppressing renal fibrosis. Stem Cells Translational Medicine. 2024
  • Tatsuya Maruhashi, Masato Kajikawa, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Yu Hashimoto, Aya Mizobuchi, Shunsuke Tanigawa, Farina Mohamad Yusoff, Yukiko Nakano, et al. Upstroke time is a more useful marker of atherosclerosis than percentage of mean arterial pressure for detecting coronary artery disease in subjects with a normal ankle-brachial index. Hypertension research : official journal of the Japanese Society of Hypertension. 2024
  • So Kurawaki, Ayumu Nakashima, Naoki Ishiuchi, Ryo Kanai, Satoshi Maeda, Kensuke Sasaki, Takao Masaki. Mesenchymal stem cells pretreated with interferon-gamma attenuate renal fibrosis by enhancing regulatory T cell induction. Scientific Reports. 2024
  • Masato Kajikawa, Tatsuya Maruhashi, Shinji Kishimoto, Takayuki Yamaji, Takahiro Harada, Yusuke Saito, Aya Mizobuchi, Shunsuke Tanigawa, Yukiko Nakano, Kazuaki Chayama, et al. A Body Shape Index as a Simple Anthropometric Marker of Abdominal Obesity and Risk of Cardiovascular Events. The Journal of clinical endocrinology and metabolism. 2024
  • Rei Takeda, Kazuya Takahashi, Andreas Kronbichler, Daiichiro Akiyama, Shunichiro Hanai, Yoshiaki Kobayashi, Ayako Matsuki, Takeshi Umibe, Chisaki Ito, Toyohiko Sugimoto, et al. Development of a Kidney Prognostic Score in a Japanese Cohort of Patients With Antineutrophil Cytoplasmic Autoantibody Vasculitis. Kidney international reports. 2024. 9. 3. 611-623
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MISC (49)：
  • 浜田 信行, 川野 樹一朗, 野村 崇治, 古川 恭治, ユソフ・ファリナ, 丸橋 達也, 前田 誠, 中島 歩, 東 幸仁. 放射線を照射した野生型マウスの大動脈に生じる血管損傷 線量遷延の低減・増強効果(Sparing and enhancing effects of radiation dose protraction for vascular damage in the aorta of wild-type mice). 日本放射線影響学会大会講演要旨集. 2022. 65回. 199-199
  • 浜田 信行, 川野 樹一朗, 野村 崇治, 古川 恭治, ユソフ・ファリナ, 丸橋 達也, 前田 誠, 中島 歩, 東 幸仁. 放射線を照射した野生型マウスの大動脈に生じる血管損傷 線量遷延の低減・増強効果(Sparing and enhancing effects of radiation dose protraction for vascular damage in the aorta of wild-type mice). 日本放射線影響学会大会講演要旨集. 2022. 65回. 199-199
  • Kishimoto S, Kinoshita Y, Matsumoto T, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Takaeko Y, Kihara Y, Chayama K, et al. Effects of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin on Blood Pressure in Hypertensive Patients with Type 2 Diabetes Mellitus. American journal of hypertension. 2019. 32. 695-702
  • Maruhashi T, Kajikawa M, Kishimoto S, Matsui S, Hashimoto H, Takaeko Y, Aibara Y, Yusoff FM, Hidaka T, Chayama K, et al. Relationships Between Calcium Channel Blockers and Vascular Function Tests. American journal of hypertension. 2019. 32. 640-648
  • 梶川 正人, 丸橋 達也, 日高 貴之, 中野 由紀子, 栗栖 智, 岸本 真治, 松井 翔吾, 橋本 東樹, 高永甲 有司, Yusoff Farina Mohamad, et al. Coffee with a High Content of Chlorogenic Acids and Low Content of Hydroxyhydroquinone Ameliorates Postprandial Endothelial Dysfunction(和訳中). 日本循環器学会学術集会抄録集. 2019. 83回. OJ20-2
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Books (23)：
  • CKD-MBD 3rd Edition
    日本メディカルセンター 2018
  • 臨床雑誌内科
    南江堂 2015
  • 腎臓内科・泌尿器内科
    科学評論社 2015
  • Hyaluronan-responsive genes in osteoarthritic cartilage of rat joints
    The Japanese Society for Clinical Rheumatology and Related Research 2013
  • 血液透析患者における肝炎ウイルス感染率と生命予後
    2013
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Lectures and oral presentations  (94)：
  • 放射線を照射した野生型マウスの大動脈に生じる血管損傷:線量遷延の低減・増強効果
    (第3回日本放射線安全管理学会・日本保健物理学会合同大会 2021)
  • Mesenchymal stem cells cultured in serum-free medium suppress murine bleomycin-induced pulmonary fibrosis by enhancing regulatory T cell induction
    (The 25th Congress of the Asian Pacific Society of Respirology 2021)
  • 高血圧患者の階段の使用と血管機能について
    (第125回日本内科学会中国地方会 2021)
  • ヒストンH3K4トリメチル化酵素(MLL1/WDR5)の阻害は,老化因子p16の発現を抑制し,メチルグリオキサール(MGO)による腹膜線維化を改善する
    (第27回日本腹膜透析医学会学術集会・総会 2021)
  • 無血清培地で培養した間葉系幹細胞を用いたブレオマイシン肺線維症に対する治療効果
    (第30回Pneumo Forum 2021)
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Education (2)：
  • 2004 - 2008 Hiroshima University
  • 1993 - 1999 Yamanashi Medical University
Professional career (1)：
  • 博士(医学) (広島大学)
Work history (9)：
  • 2023 - 現在 University of Yamanashi Graduate Faculty of Interdisciplinary Research Faculty of Medicine Professor
  • 2017 - 現在 Hiroshima University Graduate School of Biomedical and Health Sciences(Medicine) Professor, Collaborative Research Laboratory
  • 2015 - 2017 Hiroshima University Research Institute for Radiation Biology and Medicine Assistant Professor (Special Appointment)
  • 2011 - 2015 Hiroshima University Hospital Medical Center for Translational and Clinical Research Assistant Professor (Special Appointment)
  • 2010 - 2011 Hiroshima University Graduate School of Biomedical Sciences Assistant Professor
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Awards (6)：
  • 2015/06 - 日本腎臓学会 第58回 日本腎臓学術総会 会長賞
  • 2013/07 - 第5回 腎疾患と高血圧研究会 研究賞
  • 2011 - 万有財団 2011年度 Banyu Foundation Research Grant
  • 2011 - 第15回 広仁会基礎医学賞
  • 2010/10 - 第40回 日本腎臓学会西部学術大会 最優秀演題賞
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Association Membership(s) (5)：
The Molecular Biology Society of Japan ,  The Japanese Society for Regenerative Medicine ,  The Japanese Society of Internal Medicine ,  Japanese Society of Nephrology ,  The Japanese Society for Dialysis Therapy
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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