Rchr
J-GLOBAL ID:201301083997518423   Update date: Feb. 06, 2024

Inaba Mutsumi

イナバ ムツミ | Inaba Mutsumi
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/00183179.ja.html
Research field  (3): Applied molecular and cellular biology ,  Animal production science ,  Veterinary medicine
Research keywords  (26): 小胞体関連分解 ,  遺伝性疾患 ,  赤血球 ,  赤血球膜 ,  膜骨格 ,  バンド3 ,  牛 ,  小胞体 ,  小胞輸送 ,  遺伝性素因 ,  ヒドロキシノネナール ,  酸化障害 ,  獣医学 ,  赤芽球系分化 ,  産業動物 ,  アニオン・トランスポート ,  陰イオン輸送 ,  膜タンパク質 ,  脂質過酸化 ,  サイトカイン ,  ジェノミクス ,  病態 ,  細胞膜 ,  膜骨格タンパク質 ,  伴侶動物 ,  酸塩基平衡
Research theme for competitive and other funds  (43):
  • 2023 - 2026 Mechanisms of TSPO2-mediated cholesterol redistribution in erythroblasts required for their effective proliferation and maturation
  • 2021 - 2024 核内受容体REV-ERBによる免疫記憶制御の分子基盤の解明とワクチン療法への応用
  • 2020 - 2023 Mechanism for the roles of cholesterol-binding membrane protein TSPO2 in terminal erythroid differentiation
  • 2017 - 2021 Immunological memory formation through nuclear receptors and its application for vaccine therapy
  • 2016 - 2019 TRIM-SUMO-11S proteasome pathway: a possible axis for ubiquitylation-independent endoplasmic reticulum-associated degradation of AE1 mutants
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Papers (71):
  • Shangyi Wang, Mina Kozai, Masaya Hiraishi, Md. Zahir Uddin Rubel, Osamu Ichii, Mutsumi Inaba, Kazuhiro Matsuo, Kensuke Takada. Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis. Frontiers in Immunology. 2024. 15
  • Yuqi Chen, Kosuke Miyazono, Yayoi Otsuka, Mariko Kanamori, Aozora Yamashita, Nobuto Arashiki, Takehisa Matsumoto, Kensuke Takada, Kota Sato, Narla Mohandas, et al. Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability. Journal of Biological Chemistry. 2023. 299. 2. 102877-102877
  • Shangyi Wang, Mina Kozai, Hironobu Mita, Zimeng Cai, Md. Abdul Masum, Osamu Ichii, Kensuke Takada, Mutsumi Inaba. REV-ERB agonist suppresses IL-17 production in γδT cells and improves psoriatic dermatitis in a mouse model. Biomedicine & Pharmacotherapy. 2021. 144. 112283-112283
  • Zimeng Cai, Taishin Ishibashi, Mina Kozai, Hironobu Mita, Shangyi Wang, Kensuke Takada, Mutsumi Inaba. ROR agonist hampers the proliferation and survival of postactivated CD8 + T cells through the downregulation of cholesterol synthesis-related genes. Immunology & Cell Biology. 2021. 99. 3. 288-298
  • Benjaporn Kiatpakdee, Kota Sato, Yayoi Otsuka, Nobuto Arashiki, Yuqi Chen, Takuya Tsumita, Wataru Otsu, Akito Yamamoto, Reo Kawata, Jumpei Yamazaki, et al. Cholesterol-binding protein TSPO2 coordinates maturation and proliferation of terminally differentiating erythroblasts. The Journal of Biological Chemistry. 2020. 295. 23. 8048-8063
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MISC (88):
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Books (10):
  • 獣医内科学
    文永堂出版 2022
  • Chapter 30: Erythrocyte membrane defects. In Schalm's Veterinary Hematology, 7th ed. (Brooks, M. B., Harr, K. E., Seelig, D. M., Wardrop, K. J., and Weiss, D. J. eds.) pp. 238-247
    Wiley-Blackwell, Hoboken, NJ. 2022
  • 主要症状を基礎にした牛の臨床
    デーリィマン社 2020 ISBN:9784864530705
  • 子牛の医学 : 胎子期から出生・育成期まで = The calf : medicine from the birth to first childbirth
    緑書房 2014 ISBN:9784895310499
  • Erythrocyte membrane defects. In Schalm's Veterinary Hematology, 6th ed. (Weiss, D. and Wardrop, K. J. eds.)
    Wiley-Blackwell, Hoboken, NJ 2010
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Lectures and oral presentations  (1):
  • REV-ERBアゴニストはγδT17細胞を抑制しマウスモデルの乾癬性皮膚炎を改善する(REV-ERB agonist suppresses γδ T17 cells and improves psoriatic dermatitis in a mouse model)
    (日本獣医学会学術集会講演要旨集 2022)
Education (3):
  • 1984 - 1985 Hokkaido University Graduate School of Veterinary Medicine
  • 1982 - 1984 Hokkaido University Graduate School of Veterinary Medicine
  • 1978 - 1982 Hokkaido University School of Veterinary Medicine
Professional career (1):
  • 獣医学博士
Work history (7):
  • 2002/09 - 現在 北海道大学 (連合)獣医学研究科 教授
  • 2013/04 - 2017/03 Hokkaido University Graduate School of Veterinary Medicine/School of Veterinary Medicine Dean
  • 2010/04 - 2017/03 北海道大学 教育研究評議会 委員
  • 2008/04 - 2010/03 北海道大学 大学院獣医学研究科附属動物病院 病院長
  • 1994/04 - 2002/08 The University of Tokyo Graduate School of Agricultural and Life Sciences
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Association Membership(s) (5):
JAPAN VETERINARY MEDICAL ASSOCIATION ,  American Society for Biochemistry and Molecular Biology ,  THE MEMBRANE SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  JAPANESE SOCIETY OF VETERINARY SCIENCE
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