Rchr
J-GLOBAL ID:201301087868842570   Update date: Aug. 28, 2020

Tsuru Michiyo

ツル ミチヨ | Tsuru Michiyo
Affiliation and department:
Job title: Lecturer
Homepage URL  (2): http://www.med.kurume-u.ac.jp/med/sgc/index.htmlhttp://www.med.kurume-u.ac.jp/med/sgc/index.html
Research field  (9): Statistical science ,  Other ,  Orthopedics ,  Tumor diagnostics and therapeutics ,  Biophysics ,  Functional biochemistry ,  Sports science ,  Tumor biology ,  Healthcare management, medical sociology
Research keywords  (14): Drug Delivery System, ,  Drug Delivery System, DDS ,  Proof of Concept: POC ,  first in human: FIH ,  nonclinical test ,  Cancer Epithelial-Mesenchymal Transition ,  Ubiquitin ,  ligament ,  Mesenchymal stem cells ,  ossification of posterior longitudinal ligament ,  Protein modification ,  proteomics ,  miRNA ,  micro RNA
Research theme for competitive and other funds  (5):
  • 2012 - 2016 The world's first, ligament ossification blocker pharmaceutical the development by stem cell derived ligament tissues making success
  • 2009 - 2014 Discovery and the elucidation of a mechanism of an incurable disease and ossification-of-posterior-longitudinal-ligament specific protein
  • 2004 - 2009 A New Preventative Strategy Targeting a Specific Novel Protein against Human Bone Metastases
  • 2003 - 2009 Clinicalbiostatistics core talented-people training unit
  • 2002 - Strut Allograft Healing to the Femur with recombinant Human OP-1.
Papers (19):
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MISC (64):
  • 津留 美智代. 20190521. Japan Society of Clinical Proteogenomics (JSCP). 2019. 2019. 0
  • 津留 美智代. 20190521. Japan Society of Clinical Proteogenomics (JSCP). 2019. 2019. 0
  • Michiyo Tsuru. http://www.jsbmr.jp/1st_author/328_mtsuru.html. http://www.jsbmr.jp/1st_author/328_mtsuru.html. 2018
  • 津留 美智代, 小野 睦, 内田 研造, 戸山 芳昭, 永田 見生. ゲノムビッグデータとバイオインフォマティクス 新たな創薬へ 後縦靱帯骨化症モデルマウスの作製による治療製剤への開発研究. 日本整形外科学会雑誌. 2015. 89. 8. S1530-S1530
  • 津留 美智代, 志波 直人, 永田 見生. Elucidation of mechanisms through discovery of bone metastasis-specific protein. 日本整形外科学会雑誌. 2013. 87. 10. 859-864
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Patents (3):
Books (3):
  • AGEs and Aging
    Medical Review 2012 ISBN:9784779210051
  • Forefront of disease proteomics
    2004
  • Advances in Spinal Fusion: Molecular Science, BioMechanics, and Clinical Management
    Cambridge Scientific, Inc. c/o M&N Toscano 2003 ISBN:0824743105
Lectures and oral presentations  (49):
  • Elucidation of ligament ossification mechanism using posterior longitudinal ligament ossification model mouse
    (The 37th Annual Meeting of the Japanese Society for Bone Metabolism 2019)
  • Discovery of the cause protein of the ossification of posterior longitudinal ligament; OPLL (public welfare labor designation intractable disease) and proof elucidation with the model mouse
    (The 15th Annual Meeting of Japan Society for Clinical Proteogenomics 2019)
  • Retrospective proteomic analysis of a novel, cancer metastasis-promoting RGD-containing peptide
    (The 15th Annual Meeting of Japan Society for Clinical Proteogenomics 2019)
  • Statistical search method for disease-specific proteins
    (Togo - Japan sponsored by the Japan Science and Technology Agency (JST), Ministry of Education, Culture, Sports, Science and Technology and the Ministry of Health, Labor and Welfare Co-organized Research Results Fruitful Report 2016)
  • Nonclinical proof of concept study to develop a formulation for treatment of longitudinal ligament ossification.
    (3rd MEXT Ministry of Health, Labor and Welfare Ministry of Health, Labor and Welfare Innovative Medical Technology Creation Base Project. TR Promotion Joint Forum Medical Innovation from Accademia - Japan and the World - 2015)
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Works (5):
  • Rheumatoid arthritis clinical trial of hesperidin,
    Ezaki Glico Co 2002 -
  • OP-1 Strut Allograft Healing to the Femur with recombinant Human
    Nippon Striker Co., Lt 2002 -
  • FOY Clinical Trial
    Ono Pharmaceutical Co, L 1990 - 1991
  • Translational research
    Michiyo Tsuru
  • proof of concept, Non-clinical study
    Michiyo Tsuru, JRA
Education (1):
  • 2003 - 2003 Kitasato University doctor of life sciences
Professional career (1):
  • Ph.D. (Life Science Dr)
Work history (8):
  • 2014/04 - 現在 Kurume University
  • 2008 - 2012 Kurume University
  • 2003/12 - 2008/03 Kurume University
  • 2003/12 - 2008/03 Ministry of Education,Culture,Sports,Science and Technology
  • 2003/07 - 2003/11 Kurume University
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Awards (4):
  • 2018/11 - Japan Osteoporosis Foundation Clinical study on osteoporosis
  • 2006 - Research Award, AstraZeneca Research Grant. Research Award, AstraZeneca Research Grant. New preventative strategy for human bone metastases targeting a specific novel protein.
  • 2005 - Research Award, Lilly Felloeship and Research Grant Program for Bone & Mineral Research. Research Award, Lilly Felloeship and Research Grant Program for Bone & Mineral Research.
  • 2002/05 - Research Award, Second European Conference on Bone Morphogenetic Proteins. Research Award, Second European Conference on Bone Morphogenetic Proteins. Gene Therapy using in vivo Electroporation of Human BMP-2 Gene in Klotho mice.
Association Membership(s) (8):
JACCRO ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  JAPANESE SOCIETY OF GASTROENTEROLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH ,  THE JAPANESE ORTHOPAEDIC ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  Japan Society for Clinical Proteogenomics
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