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J-GLOBAL ID：201302201403377066   Reference number：13A0985146

UBC9 Regulates the Stability of XBP1, a Key Transcription Factor Controlling the ER Stress Response

UBC9はERストレス応答を調節する主要転写因子XBP1の安定性を制御する

Author (7)： UEMURA Aya (Dep. of Biophysics, Graduate School of Sci., Kyoto Univ.) ,  TANIGUCHI Mai (Dep. of Molecular Biochemistry, Graduate School of Life Sci., Univ. of Hyogo) ,  MATSUO Yusaku (Dep. of Molecular Biochemistry, Graduate School of Life Sci., Univ. of Hyogo) ,  OKU Masaya (Dep. of Biophysics, Graduate School of Sci., Kyoto Univ.) ,  WAKABAYASHI Sadao (Dep. of Molecular Biochemistry, Graduate School of Life Sci., Univ. of Hyogo) ,  YOSHIDA Hiderou (Dep. of Biophysics, Graduate School of Sci., Kyoto Univ.) ,  YOSHIDA Hiderou (Dep. of Molecular Biochemistry, Graduate School of Life Sci., Univ. of Hyogo)
Material： Cell Structure and Function (Web)  (Cell Struct Funct (Web))
Volume： 38  Issue： 1  Page： 67-79 (J-STAGE)  Publication year： 2013 
JST Material Number： U0126A  ISSN： 1347-3700  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *ER stress ,...
Semi thesaurus term： Unfolded Protein Response ,...

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JST classification (3)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q)

Substance index (1)： Thapsigargin

Reference (46)：

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• Calfon, M., Zeng, H., Urano, F., Till, J.H., Hubbard, S.R., Harding, H.P., Clark, S.G., and Ron, D. 2002. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature, 415: 92窶錀96.
• Chakrabarti, S.R., Sood, R., Ganguly, S., Bohlander, S., Shen, Z., and Nucifora, G. 1999. Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9. Proc. Natl. Acad. Sci. USA, 96: 7467窶錀7472.

Terms in the title (7)： Ubc9 ,  ERストレス ,  応答 ,  調節 ,  転写因子 ,  XBP1 ,  安定性