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J-GLOBAL ID：201302204212319103   Reference number：13A1937883

Involvement of reactive oxygen species in osteoblastic differentiation of MC3T3-E1 cells accompanied by mitochondrial morphological dynamics

ミトコンドリアの形態学的ダイナミクスに伴って発生するMC3T3-E1細胞の骨芽細胞分化における反応性酸素種の関与

Author (4)： ARAKAKI Naokatu (Dep. of Molecular Cell Biology and Medicine, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School ...) ,  YAMASHITA Arisa (Dep. of Molecular Cell Biology and Medicine, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School ...) ,  NIIMI Shingo (Div. of Biological Chemistry and Biologicals, National Inst. of Health Sciencses, Tokyo 158-8501, JPN) ,  YAMAZAKI Tetsuo (Dep. of Molecular Cell Biology and Medicine, Inst. of Health Biosciences, The Univ. of Tokushima Graduate School ...)
Material： Biomedical Research  (Biomed Res)
Volume： 34  Issue： 3  Page： 161-166 (J-STAGE)  Publication year： 2013 
JST Material Number： Z0236B  ISSN： 0388-6107  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *osteoblast ,...
Semi thesaurus term： *形態変化 ,...

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JST classification (3)： Cell physiology in general  (EF02010S) ,  Biophylaxis and immune systems in general  (ED01010F) ,  Function of cell components  (EF03060C)

Substance index (1)： Acetylcysteine

Reference (29)：

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• 2. Barsoum MJ, Yuan H, Gerenser AA, Liot G, Kushnareva Y, Graber S, Kovacs I, Lee WD, Waggoner J, Cui J, White AD, Bossy BM, Martinou JC, Youle RJ, Lipton SA, Ellisman MH, Perkins GA and Bossy-Wetzel E (2006) Nitric oxideinduced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J 25, 3900-3911.
• 3. Chen JR, Shankar K, Nagarajan S, Badger TM and Ronis MJ (2008) Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of transcription 3/receptor activator of nuclear factor-kappaB ligand signaling cascade. J Pharmacol Exp Ther 324, 50-59.
• 4. Chua CC, Chua BH, ChenZ, Landy C and Hamdy RC (2003) Dexamethasone induces caspase activation in murine osteoblastic MC3T3-E1 cells. Biochim Biophys Acta 1642, 79-85.
• 5. de Brito OM and Scorrano L (2010) An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship. EMBO J 29, 2715-2723.

Terms in the title (6)： ミトコンドリア ,  形態学 ,  ダイナミクス ,  MC3T3-E1細胞 ,  骨芽細胞分化 ,  反応性酸素種