Art

J-GLOBAL ID：201302209199352238   Reference number：13A1055663

The Hallmarks of Aging

老化の特徴

Author (10)： LOPEZ-OTIN Carlos (Departamento de Bioquimica y Biologia Molecular, Instituto Universitario de Oncologia (IUOPA), Universidad de Oviedo ...) ,  BLASCO Maria A. (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Res. Centre (CNIO), Madrid, ESP) ,  PARTRIDGE Linda (Max Planck Inst. for Biology of Ageing, Cologne, DEU) ,  PARTRIDGE Linda (Inst. of Healthy Ageing, Dep. of Genetics, Evolution and Environment, Univ. Coll. London, London, GBR) ,  SERRANO Manuel (Tumor Suppression Group, Molecular Oncology Program, Spanish National Cancer Res. Centre (CNIO), Madrid, ESP) ,  KROEMER Guido (INSERM, U848, Villejuif, FRA) ,  KROEMER Guido (Metabolomics and Cell Biology Platforms, Inst. Gustave Roussy, Villejuif, FRA) ,  KROEMER Guido (Centre de Rech. des Cordeliers, Paris, FRA) ,  KROEMER Guido (Pole de Biologie, Hopital Europeen Georges Pompidou, AP-HP, Paris, FRA) ,  KROEMER Guido (Univ. Paris Descartes, Sorbonne Paris Cite, Paris, FRA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 153  Issue： 6  Page： 1194-1217  Publication year： Jun. 06, 2013 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 文献レビュー  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *senile change ,  human ,  molecular genetic phenomenon ,  dysfunction ,  cell aging ,  stem cell ,  genetics ,  protein metabolism ,  *DNA lesion ,  DNA ,  active oxygen ,  Cell Nucleus ,  chemical modification ,  post-translational modification ,  ADP ribosyltransferase ,  histone deacetylase ,  lifetime ,  chaperone protein ,  IGF1 ,  Genomic Instability ,  Cell Communication ,  nuclear DNA ,  DNA, Mitochondrial ,  histone modification ,  insulin signaling ,  Genetic Variation ,  Cell Physiological Phenomena ,  Signal Transduction ,  Telomere Shortening ,  Sirtuin 6 ,  natural science ,  factor ,  bioactive factor ,  growth factor ,  cytokine
Semi thesaurus term： variation(biology) ,  cell physiology ,  cellular signal transduction ,  telomere shortening ,  mitochondrial dysfunction ,  epigenetic mechanisms ,  Sirt6

JST classification (3)： Aging and death  (EJ16040S) ,  Geriatrics  (GC09000X) ,  Molecular genetics in general  (EC02010J)

Terms in the title (1)： 老化