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J-GLOBAL ID:201302209740370600   Reference number:13A1401340

Analytical determination of specific 4,4′-methylene diphenyl diisocyanate hemoglobin adducts in human blood

ヒトの血液中の特異な4,4′-メチレンジフェニルメタンジイソシアネートヘモグロビン付加体の定量
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Material:
Volume: 405  Issue: 23  Page: 7205-7213  Publication year: Sep. 2013 
JST Material Number: E0425B  ISSN: 1618-2642  Document type: Article
Article type: 原著論文  Country of issue: Germany, Federal Republic of (DEU)  Language: ENGLISH (EN)
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Miscellaneous analytical methods of organic compounds  ,  Basic biopharmacy 
Reference (27):
  • European Chemicals Agency (2008) Data on manufacture, import, export, uses and releases of 4,4’-diaminodiphenylmethane as well as information on potential alternatives to its use. http://echa.europa.eu/documents/10162/13640/tech_rep_mda_en.pdf. Accessed 11 Mar 2013)
  • Wisneswski AV, Xu L, Robinson E, Liu J, Redlich CA, Herrick CA (2011) Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: Albumin as a carrier protein connecting skin exposure to subsequent respiratory responses. J Occup Med Toxicol 6:6
  • Pauluhn J, Leng G (2003) Concentration-dependence of biomarkers of exposure of methylenediphenyl-diisocyanate following acute inhalation exposure of rats. Toxicology 185:35-48
  • Sabbioni G (1992) Hemoglobin binding of monocyclic aromatic amines: Molecular dosimetry and quantitative structure activity relationships fort the N-oxidation. Chem Biol Interact 81:91-117
  • Reisser M, Schmidt BF, Brown WE (2002) Synthesis, characterization and solvolysis of mono- and bis-S-(glutathionyl) adducts of methylene-bis-(phenylisocyanate) (MDI). Chem Res Toxicol 15:1235-1241
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