Art

J-GLOBAL ID：201302210746327365   Reference number：12A1796011

Association of ABCC2 Genotype with Efficacy of First-line FOLFIRI in Japanese Patients with Advanced Colorectal Cancer

進行大腸癌の日本人患者におけるファーストラインFOLFIRI療法の有効性とABCC2遺伝子型の関連

Author (12)： AKIYAMA Yuko (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  AKIYAMA Yuko (Project Res. Lab., Res. Center for Genomic Medicine, Saitama Medical Univ.) ,  FUJITA Ken-ichi (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  FUJITA Ken-ichi (Project Res. Lab., Res. Center for Genomic Medicine, Saitama Medical Univ.) ,  ISHIDA Hiroo (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SUNAKAWA Yu (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  YAMASHITA Keishi (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  KAWARA Kaori (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  MIWA Keisuke (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SAJI Shigehira (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SASAKI Yasutsuna (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SASAKI Yasutsuna (Project Res. Lab., Res. Center for Genomic Medicine, Saitama Medical Univ.)
Material： Drug Metabolism and Pharmacokinetics  (Drug Metab Pharmacokinet)
Volume： 27  Issue： 3  Page： 325-335 (J-STAGE)  Publication year： 2012 
JST Material Number： X0758A  ISSN： 1347-4367  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： ABCC2 gene ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=12A1796011&from=J-GLOBAL&jstjournalNo=X0758A") }}

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (3)： Fluorouracil ,  Levofolinate calcium ,  CPT-11

Reference (41)：

• 1) Kudoh, S., Fujiwara, Y., Takada, Y., Yamamoto, H., Kinoshita, A., Ariyoshi, Y., Furuse, K. and Fukuoka, M.: Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. West Japan Lung Cancer Group. J. Clin. Oncol., 16: 1068–1074 (1998).
• 2) Negoro, S., Fukuoka, M., Masuda, N., Takada, M., Kusunoki, Y., Matsui, K., Takifuji, N., Kudoh, S., Niitani, H. and Taguchi, T.: Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer. J. Natl. Cancer Inst., 83: 1164–1168 (1991).
• 3) Rougier, P., Van Cutsem, E., Bajetta, E., Niederle, N., Possinger, K., Labianca, R., Navarro, M., Morant, R., Bleiberg, H., Wils, J., Awad, L., Herait, P. and Jacques, C.: Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet, 352: 1407–1412 (1998).
• 4) Sparreboom, A., Fujita, K. and Zamboni, W. C.: Topoisomerase I-Targeting Drugs. In Chabner, B. A. and Longo, D. L. (eds.): <i>Cancer Chemotherapy and Biotherapy Principles and Practice</i>, Philadelphia: Lippincott Williams & Wilkins, 2010, pp. 342–355.
• 5) Nozawa, T., Minami, H., Sugiura, S., Tsuji, A. and Tamai, I.: Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. Drug Metab. Dispos., 33: 434–439 (2005).

Terms in the title (6)： 進行大腸癌 ,  日本人 ,  患者 ,  FOLFIRI療法 ,  有効性 ,  ABCC2遺伝子