In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction

SHIMA Fumi; YOSHIKAWA Yoko; YE Min; ARAKI Mitsugu; MATSUMOTO Shigeyuki; LIAO Jingling; HU Lizhi; SUGIMOTO Takeshi; IJIRI Yuichi; TAKEDA Azusa; NISHIYAMA Yuko; SATO Chie; MURAOKA Shin; TAMURA Atsuo; OSODA Tsutomu; TSUDA Ken-ichiro; MIYAKAWA Tomoya; FUKUNISHI Hiroaki; SHIMADA Jiro; KUMASAKA Takashi; YAMAMOTO Masaki; KATAOKA Tohru

Art

J-GLOBAL ID：201302213674021184 Reference number：13A0979448

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction

Ras-エフェクター相互作用の阻害により抗腫瘍活性を示す小分子Ras阻害剤のインシリコ発見

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Volume： 110 Issue： 20 Page： 8182-8187 Publication year： May. 14, 2013
JST Material Number： D0387A ISSN： 0027-8424 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Basic research of antitumor(=antineoplastic)drugs , Basic oncology in general

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