Art

J-GLOBAL ID：201302214051863644   Reference number：13A1299130

新たな作用機序による経口血糖降下薬《選択的SGLT2阻害薬》の有効性と安全性

Author (1)： KAKU KOHEI (川崎医大)
Material： 診療と新薬  (Medical Consultation & New Remedies)
Volume： 50  Issue： 7  Page： 607-614  Publication year： Jul. 28, 2013 
JST Material Number： Z0942A  ISSN： 0037-380X  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *hypoglycemic drug ,...
Semi thesaurus term： insulin ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=13A1299130&from=J-GLOBAL&jstjournalNo=Z0942A") }}

JST classification (1)： Clinical application of drugs acting on carbohydrate metabolism  (GW13030B)

Substance index (1)： Glucose

Reference (22)：

• 1) Kim Y, Babu AR: Clinical potential of sodium-glucose cotransporter 2 inhibitors in the management of type 2 diabetes. Diabetes Metab Syndr Obes 2012; 5: 313-27.
• 2) Chao EC, Henry RR: SGLT2 inhibition--a novel strategy for diabetes treatment. Nat Rev Drug Discov 2010; 9: 551-9.
• 3) Tabatabai NM, Sharma M, Blumenthal SS, et al: Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic Zucker rats. Diabetes Res Clin Pract 2009; 83: e27-30.
• 4) Osorio H, Bautista R, Rios A, et al: Effect of phlorizin on SGLT2 expression in the kidney of diabetic rats. J Nephrol 2010; 23: 541-6.
• 5) Vestri S, Okamoto MM, de Freitas HS, et al: Changes in sodium or glucose filtration rate modulate expression of glucose transporters in renal proximal tubular cells of rat. J Membr Biol 2001; 182: 105-12.

Terms in the title (5)： 作用機序 ,  経口血糖降下薬 ,  SGLT2阻害薬 ,  有効性 ,  安全性