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J-GLOBAL ID:201302218447342421   Reference number:13A1888385

Association analysis of the DISC1 gene with schizophrenia in the Japanese population and DISC1 immunoreactivity in the postmortem brain

日本人集団におけるDISC1遺伝子と統合失調症との関連性解析および死後脳におけるDISC1免疫反応性
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Material:
Volume: 77  Issue:Page: 222-227  Publication year: Dec. 2013 
JST Material Number: D0210C  ISSN: 0168-0102  Document type: Article
Article type: 原著論文  Country of issue: Netherlands (NLD)  Language: ENGLISH (EN)
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Basic psychiatry  ,  Genetic variation 
Reference (29):
  • Austin, C.P., Ky, B., Ma, L., Morris, J.A., Shughrue, PJ., 2004. Expression of Disruptedin-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development. Neuroscience 124, 3-10.
  • Blackwood, D.H., Fordyce, A., Walker, M.T., St Clair, D.M., Porteous, DJ., Muir, W.J., 2001. Schizophrenia and affective disorders-cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am. J. Hum. Genet. 69, 428-433.
  • Brandon, N.J., Sawa, A., 2011. Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat. Rev. Neurosci. 12, 707-722.
  • Callicott, J.H., Straub, R.E., Pezawas, L., Egan, M.F., Mattay, V.S., Hariri, A.R., Verchinski, B.A., Meyer-Lindenberg, A., Balkissoon, R., Kolachana, B., Goldberg, T.E., Weinberger, D.R., 2005. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 102, 8627-8632.
  • Chubb, J.E., Bradshaw, NJ., Soares, D.C., Porteous, DJ., Millar, J.K., 2008. The DISC locus in psychiatric illness. Mol. Psychiatry 13, 36-64.
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