Art

J-GLOBAL ID：201302234169097980   Reference number：13A1228985

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

CRISPRを利用した真核生物におけるモジュール式RNA誘導性転写制御

Author (40)： GILBERT Luke A. (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  GILBERT Luke A. (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  GILBERT Luke A. (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  GILBERT Luke A. (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  LARSON Matthew H. (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  LARSON Matthew H. (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  LARSON Matthew H. (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  LARSON Matthew H. (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  MORSUT Leonardo (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  MORSUT Leonardo (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  LIU Zairan (Peking Univ., Beijing China) ,  BRAR Gloria A. (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  BRAR Gloria A. (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  BRAR Gloria A. (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  BRAR Gloria A. (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  TORRES Sandra E. (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  TORRES Sandra E. (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  TORRES Sandra E. (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  TORRES Sandra E. (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  STERN-GINOSSAR Noam (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  STERN-GINOSSAR Noam (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  STERN-GINOSSAR Noam (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  STERN-GINOSSAR Noam (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  BRANDMAN Onn (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  BRANDMAN Onn (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  BRANDMAN Onn (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  BRANDMAN Onn (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  WHITEHEAD Evan H. (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  WHITEHEAD Evan H. (UCSF Center for Systems and Synthetic Biology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  WHITEHEAD Evan H. (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  DOUDNA Jennifer A. (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  DOUDNA Jennifer A. (California Inst. for Quantitative Biomedical Res., San Francisco, CA 94158, USA) ,  DOUDNA Jennifer A. (Center for RNA Systems Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  DOUDNA Jennifer A. (Dep. of Molecular and Cellular Biology, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  DOUDNA Jennifer A. (Dep. of Chemistry, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  DOUDNA Jennifer A. (Dep. of Bioengineering, Univ. of California, Berkeley, Berkeley, CA 94720, USA) ,  DOUDNA Jennifer A. (Physical Biosciences Div., Lawrence Berkeley National Lab., Berkeley, CA 94720, USA) ,  LIM Wendell A. (Dep. of Cellular and Molecular Pharmacology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  LIM Wendell A. (Howard Hughes Medical Inst., Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  LIM Wendell A. (UCSF Center for Systems and Synthetic Biology, Univ. of California, San Francisco, San Francisco, CA 94158, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 154  Issue： 2  Page： 442-451  Publication year： Jul. 18, 2013 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *palindrome ,  *transcription (genetics) ,  Saccharomyces cerevisiae ,  *caspase ,  HEK293 cell ,  gene targetting ,  HeLa cell ,  Chemokine Receptors ,  CD antigen ,  transferrin receptor ,  DNA binding protein ,  *nucleotide sequence ,  Gene Expression Regulation ,  *CRISPR ,  transcription control ,  Gene Knockdown Technique ,  Receptors, CXCR4 ,  CD71 antigen ,  *information ,  *genetic information ,  *sequence and arrangement ,  microorganism ,  Yeasts ,  Ascomycetous yeast ,  Heredity
Semi thesaurus term： genetic regulation ,  *CRISPR ,  transcriptional regulation ,  *dCas9 ,  gene knockdown ,  CXCR4 ,  CD71 ,  KRAB

JST classification (2)： Gene expression  (EC02040Q) ,  Biological function  (EB03040U)

Terms in the title (5)： CRISPR ,  真核生物 ,  モジュール ,  RNA ,  転写制御