Art

J-GLOBAL ID：201302236236735069   Reference number：13A1747162

Measurement and correlation of solubilities of the poorly water-soluble pharmaceutical compound etodolac by addition of co-solvents

共溶媒の添加による難水溶性薬物エトドラクの溶解度の測定と相関

Author (6)： NAITO Yuma (Nihon Univ., Tokyo, JPN) ,  MATSUDA Hiroyuki (Nihon Univ., Tokyo, JPN) ,  SHIMOMURA Kazuya (Nihon Univ., Tokyo, JPN) ,  KURIHARA Kiyofumi (Nihon Univ., Tokyo, JPN) ,  TOCHIGI Katsumi (Nihon Univ., Tokyo, JPN) ,  TOMONO Kazuo (Nihon Univ., Chiba, JPN)
Material： Fluid Phase Equilibria
Volume： 357  Page： 43-49  Publication year： 2013 
JST Material Number： H0635A  ISSN： 0378-3812  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *antipyretic analgesic ,  *solubility (ratio) ,  measurement ,  correlation ,  additive effect ,  drug ,  solvent ,  cyclodextrin ,  two-component system ,  formation constant ,  correlation coefficient ,  carboxylic acid ,  nitrogen heterocyclic compound ,  oxygen heterocyclic compound ,  polynuclear aromatic compound ,  cosolvent ,  *non-steroidal anti-inflammatory drug ,  *nervinum ,  *central nervous system drug ,  *central nervous system depressant
Semi thesaurus term： *non-steroidal anti-inflammatory agent ,  poorly water soluble drug ,  stability constant

JST classification (2)： Phase equilibrium,phase diagram of multicomponent systems in general  (CB03014B) ,  Physicochemical characteristics of drugs  (GV01060M)

Substance index (1)： Etodolac

Terms in the title (5)： 共溶媒 ,  難水溶性薬物 ,  エトドラク ,  溶解度 ,  相関