Art

J-GLOBAL ID：201302247077787240   Reference number：13A0865433

Layilin, a talin-binding hyaluronan receptor, is expressed in human articular chondrocytes and synoviocytes and is down-regulated by interleukin-1β

タリン結合ヒアルロナン受容体ライリンはヒト関節軟骨細胞と滑膜細胞に発現しておりインターロイキン-1βによりダウンレギュレートされる

Author (8)： MURATA Minako (St. Marianna Univ. School of Medicine, Dep. of Frontier Medicine, Inst. of Medical Sci., 2-16-1 Sugao, 216-8511 ...) ,  YUDOH Kazuo (St. Marianna Univ. School of Medicine, Dep. of Frontier Medicine, Inst. of Medical Sci., 2-16-1 Sugao, 216-8511 ...) ,  SHIMIZU Hiroyuki (St. Marianna Univ. School of Medicine, Dep. of Orthopedic Surgery, 2-16-1 Sugao, 216-8511, Miyamae-ku, Kawasaki-shi ...) ,  BEPPU Moroe (St. Marianna Univ. School of Medicine, Dep. of Orthopedic Surgery, 2-16-1 Sugao, 216-8511, Miyamae-ku, Kawasaki-shi ...) ,  NAKAMURA Hiroshi (Nippon Medical School, Dep. of Joint Disease and Rheumatism, 1-1-5 Sendagi, 113-8603, Bunkyo-ku, Tokyo, JPN) ,  KATO Tomohiro (St. Marianna Univ. School of Medicine, Dep. of Biochemistry, 2-16-1 Sugao, 216-8511, Miyamae-ku, Kawasaki-shi ...) ,  MASUKO Kayo (St. Marianna Univ. School of Medicine, Dep. of Biochemistry, 2-16-1 Sugao, 216-8511, Miyamae-ku, Kawasaki-shi ...) ,  MASUKO Kayo (Sagami Women’s Univ., Graduate School of Nutritional Sci., Bunkyo 2-1-1, 252-0383, Minami-ku, Sagamihara-shi ...)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 23  Issue： 3  Page： 478-488  Publication year： May. 2013 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *cell adhesion receptor ,...
Semi thesaurus term： *ライリン ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=13A0865433&from=J-GLOBAL&jstjournalNo=L5142A") }}

JST classification (1)： Basic medicine on musculoskeletal system  (GG01020B)

Reference (28)：

• BOROWSKY, ML. Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles. J Cell Biol. 1998, 143, 2, 429-442
• BONO, P. Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin. Exp Cell Res. 2005, 308, 1, 177-187
• BONO, P. Layilin, a novel integral membrane protein, is a hyaluronan receptor. Mol Biol Cell. 2001, 12, 4, 891-900
• YATABE, T. Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes. Ann Rheum Dis. 2009, 68, 6, 1051-1058
• WANG, CT. High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis. Osteoarthr Cartil. 2006, 14, 12, 1237-1247

Terms in the title (7)： タリン ,  ヒアルロナン受容体 ,  ヒト ,  関節軟骨細胞 ,  滑膜細胞 ,  発現 ,  インターロイキン-1β