Art

J-GLOBAL ID：201302250940275513   Reference number：13A1304330

Angiotensin II-induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16

アンギオテンシンII誘発性の心臓肥大と線維化はFgf16欠乏マウスにおいて促進される

Author (9)： MATSUMOTO Emi (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN) ,  SASAKI Sayaka (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN) ,  KINOSHITA Hideyuki (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN) ,  KITO Takuya (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN) ,  OHTA Hiroya (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN) ,  KONISHI Morichika (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN) ,  KUWAHARA Koichiro (Kyoto Univ. Graduate School of Medicine, Kyoto, JPN) ,  NAKAO Kazuwa (Kyoto Univ. Graduate School of Medicine, Kyoto, JPN) ,  ITOH Nobuyuki (Kyoto Univ. Graduate School of Pharmaceutical Sci., Kyoto, JPN)
Material： Genes to Cells  (Genes Cells)
Volume： 18  Issue： 7  Page： 544-553  Publication year： Jul. 2013 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *heart disease ,...
Semi thesaurus term： *FGF16 ,...

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JST classification (3)： Heart  (EJ04020D) ,  Basic medicine on cardiovascular system  (GJ01020K) ,  Basic research of cardioactive drugs  (GW07020N)

Reference (31)：

• Beenken, A. & Mohammadi, M. (2009) The FGF family: biology, pathophysiology and therapy. Nat. Rev. Drug Discov. 8, 235-253.
• Bergman, M.R., Teerlink, J.R., Mahimkar, R., Li, L., Zhu, B.Q., Nguyen, A., Dahi, S., Karliner, J.S. & Lovett, D.H. (2007) Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. Am. J. Physiol. Heart Circ. Physiol. 292, H1847-H1860.
• Berk, B.C., Fujiwara, K. & Lehoux, S. (2007) ECM remodeling in hypertensive heart disease. J. Clin. Invest. 117, 568-575.
• Clark, M.S., Caldwell, R.W., Chiao, H., Miyake, K. & McNeil, P.L. (1995) Contraction-induced cell wounding and release of fibroblast growth factor in heart. Circ. Res. 76, 927-934.
• Conway, S.J. & Molkentin, J.D. (2008) Periostin as a heterofunctional regulator of cardiac development and disease. Curr. Genomics 9, 548-555.

Terms in the title (6)： アンギオテンシンII ,  心臓肥大 ,  線維化 ,  欠乏 ,  マウス ,  促進