Art

J-GLOBAL ID：201302252255647486   Reference number：13A0683488

SYNTHESIS OF 7H-THIOPYRANO[2,3-d]PYRIMIDINES BY HYDROBROMIC ACID-MEDIATED CYCLIZATION OF 1-[4-(1,1-DIMETHYLETHYLSULFANYL)PYRIMIDIN-5-YL]PROP-2-EN-1-OLS

1-[4-(1,1-ジメチルエチルスルファニル)ピリミジン-5-イル]プロポ-2-エン-1-オール類の臭化水素酸媒介環化反応による7H-チオピラノ[2,3-D]ピリミジン類の合成

Author (5)： KOBAYASHI Kazuhiro (Tottori Univ., Tottori, JPN) ,  SUZUKI Teruhiko (Tottori Univ., Tottori, JPN) ,  IMAOKA Ayumi (Tottori Univ., Tottori, JPN) ,  HIYOSHI Hidetaka (Ihara Chemical Ind. Co., Ltd., Tokyo, JPN) ,  UMEZU Kazuto (Ihara Chemical Ind. Co., Ltd., Tokyo, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 87  Issue： 4  Page： 885-895  Publication year： Apr. 01, 2013 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,  molecular structure ,  *nitrogen heterocyclic compound ,  *sulfur heterocyclic compound ,  *cyclization reaction ,  lithiation ,  enone ,  aromatic ketone ,  thiolate ,  substitution reaction ,  unsaturated aldehyde ,  unsaturated ketone
Semi thesaurus term： Chalcones ,  thiolate ,  *thiopyran derivative ,  *Pyrimidines

JST classification (2)： Pyrimidines  (CF07103W) ,  Cyclization reaction,ring-opening reaction  (CF02050I)

Substance index (5)： 2-Methylthio-4-methoxy-6-chloropyrimidine ,  3-(p-Tolyl)propenal ,  4-Chlorobenzeneacrylaldehyde ,  2-Methylthio-4-methoxy-7-(p-tolyl)-7H-thiopyrano[2,3-d]pyrimidine ,  2-Methylthio-4-methoxy-7-(4-chlorophenyl)-7H-thiopyrano[2,3-d]pyrimidine

Reference (5)：

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• 2. (a) A. A. Santilli and A. C. Scotese, J. Heterocycl. Chem., 1977, 14, 361; (b) M. G. Assy, M. M. Hassanien, and A. A. Rahman, Pharmazie, 1990, 45, 792.
• 3. K. Kobayashi, T. Suzuki, T. Kozuki, N. Matsumoto, H. Hiyoshi, and K. Umezu, Heterocycles, 2012, 85, 1405.
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Terms in the title (4)： ピリミジン ,  臭化水素酸 ,  環化反応 ,  ピリミジン類