Art

J-GLOBAL ID：201302253385111274   Reference number：13A0758882

Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure

TFG機能の阻害は小胞体構造を障害することにより遺伝性軸索変性を起す

Author (16)： BEETZ Christian (Jena Univ. Hospital, Jena, DEU) ,  JOHNSON Adam (Univ. Wisconsin School of Medicine and Public Health, WI) ,  SCHUH Amber L. (Univ. Wisconsin School of Medicine and Public Health, WI) ,  THAKUR Seema (Fortis La Femme, New Delhi, IND) ,  VARGA Rita-Eva (Jena Univ. Hospital, Jena, DEU) ,  FOTHERGILL Thomas (Univ. Wisconsin Medical School, WI) ,  HERTEL Nicole (Jena Univ. Hospital, Jena, DEU) ,  BOMBA-WARCZAK Ewa (Univ. Wisconsin Medical School, WI) ,  THIELE Holger (Univ. Cologne, Cologne, DEU) ,  NUERNBERG Gudrun (Univ. Cologne, Cologne, DEU) ,  ALTMUELLER Janine (Univ. Cologne, Cologne, DEU) ,  SAXENA Renu (Sir Ganga Ram Hospital, New Delhi, IND) ,  CHAPMAN Edwin R. (Univ. Wisconsin Medical School, WI) ,  DENT Erik W. (Univ. Wisconsin Medical School, WI) ,  NUERNBERG Peter (Univ. Cologne, Cologne, DEU) ,  AUDHYA Anjon (Univ. Wisconsin School of Medicine and Public Health, WI)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 110  Issue： 13  Page： 5091-5096  Publication year： Mar. 26, 2013 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human ,  *hereditary disease ,  *spinal cord disease ,  *diplegia ,  *spastic paralysis ,  family (home) ,  *Endoplasmic Reticulum ,  axon ,  Mutation ,  *Proteins ,  antisense RNA ,  Brain ,  deletion mutation ,  Amino Acid Sequence ,  denaturation ,  axon degeneration
Semi thesaurus term： *TFG ,  *Spastic Paraplegia, Hereditary ,  sibling

JST classification (3)： Congenital diseases,deformities in general.  (GD03010V) ,  Molecular genetics in general  (EC02010J) ,  Cell components in general  (EF03010Z)

Terms in the title (5)： 阻害 ,  小胞体 ,  障害 ,  遺伝 ,  軸索変性