Art

J-GLOBAL ID：201302256684940359   Reference number：13A0993948

A Simple Liquid Chromatography-Tandem Mass Spectrometry Method for Determination of Plasma Fentanyl Concentration in Rats and Patients with Cancer Pain

癌性疼痛のラット及びヒトにおける血漿フェンタニル濃度測定のための簡易液体クロマトグラフタンデム質量分析法

Author (11)： HISADA Tatsuya (Dep. of Pharmaceutics, Fac. of Pharmacy, Meijo Univ.) ,  HISADA Tatsuya (Dep. of Pharmacy, Toyota Memorial Hospital) ,  KATOH Miki (Dep. of Pharmaceutics, Fac. of Pharmacy, Meijo Univ.) ,  HITOSHI Kotaro (Dep. of Pharmaceutics, Fac. of Pharmacy, Meijo Univ.) ,  KONDO Yuya (Dep. of Pharmaceutics, Fac. of Pharmacy, Meijo Univ.) ,  FUJIOKA Miho (Dep. of Pharmaceutics, Fac. of Pharmacy, Meijo Univ.) ,  TOYAMA Yukio (Dep. of Pharmacy, Toyota Memorial Hospital) ,  TOYAMA Yukio (Dep. of Hospital Pharmacy, School of Medicine, Aichi Medical Univ.) ,  IEDA Hideaki (Dep. of Palliative Medicine, Nagoya Ekisaikai Hospital) ,  GOCHO Saori (Dep. of Pharmacy, Nagoya Ekisaikai Hospital) ,  NADAI Masayuki (Dep. of Pharmaceutics, Fac. of Pharmacy, Meijo Univ.)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 36  Issue： 3  Page： 412-416 (J-STAGE)  Publication year： 2013 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Rattus ,...
Semi thesaurus term： LC-MS/MS analysis

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=13A0993948&from=J-GLOBAL&jstjournalNo=S0989A") }}

JST classification (1)： Basic research of addictive analgesics and narcotics  (GW03080Z)

Substance index (1)： Fentanyl

Reference (28)：

• 1) Radbruch L, Sabatowski R, Loick G, Kulbe C, Kasper M, Grond S, Lehmann KA. Constipation and the use of laxatives: a comparison between transdermal fentanyl and oral morphine. Palliat. Med., 14, 111–119 (2000).
• 2) Ahmedzai S, Brooks D. Transdermal fentanyl versus sustained-release oral morphine in cancer pain: preference, efficacy, and quality of life. The TTS-Fentanyl Comparative Trial Group. J. Pain Symptom Manage., 13, 254–261 (1997).
• 3) Malkin JD, Ackerman SJ, Schein JR, Thornhill JC, Staats PS. Outcomes associated with fentanyl transdermal system and oxycodone controlled-release in a California medicaid population. Pain Med., 2, 246–247 (2001).
• 4) Varvel JR, Shafer SL, Hwang SS, Coen PA, Stanski DR. Absorption characteristics of transdermally administered fentanyl. Anesthesiology, 70, 928–934 (1989).
• 5) Nugent M, Davis C, Brooks D, Ahmedzai SH. Long-term observations of patients receiving transdermal fentanyl after a randomized trial. J. Pain Symptom Manage., 21, 385–391 (2001).

Terms in the title (9)： 癌性疼痛 ,  ラット ,  ヒト ,  血漿 ,  フェンタニル ,  濃度測定 ,  簡易 ,  液体クロマトグラフ ,  タンデム質量分析法