Art

J-GLOBAL ID：201302262957328376   Reference number：12A1795911

The Influence of Rhein 8-O-β-D-Glucopyranoside on the Purgative Action of Sennoside A from Rhubarb in Mice

マウスにおいてダイオウ由来のセンノシドAの下剤作用に対するレイン8-O-β-D-グルコピラノシドの影響

Author (4)： TAKAYAMA Kento (Fac. of Pharmacy and Pharmaceutical Sciences, Fukuyama Univ.) ,  TSUTSUMI Hiroyuki (Fac. of Pharmacy and Pharmaceutical Sciences, Fukuyama Univ.) ,  ISHIZU Takashi (Fac. of Pharmacy and Pharmaceutical Sciences, Fukuyama Univ.) ,  OKAMURA Nobuyuki (Fac. of Pharmacy and Pharmaceutical Sciences, Fukuyama Univ.)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 35  Issue： 12  Page： 2204-2208 (J-STAGE)  Publication year： 2012 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Rheum palmatum ,...
Semi thesaurus term： dosage dependence

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JST classification (3)： Aromatic monocyclic phenols and polyphenols  (CF05090V) ,  Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic research of drugs acting on digestive system  (GW09010Q)

Substance index (6)： Aloe emodin ,  Emodin ,  Sennoside A ,  Rhein ,  Rheinanthrone ,  Rhein glucoside

Reference (17)：

• 1) Okamura N, Miki H, Harada T, Yamashita S, Masaoka Y, Nakamoto Y, Tsuguma M, Yoshitomi H, Yagi A. Simultaneous determination of ephedrine, pseudoephedrine, norephedrine and methylephedrine in Kampo medicines by high-performance liquid chromatography. J. Pharm. Biomed. Anal., 20, 363–372 (1999).
• 2) Nakamura R, Makino B, Endo Y, Sakakibara I, Terabayashi S, Takeda S, Sasaki H. Investigation of the role of a mineral crude drug in Kampo medicine (part 1) chemical analysis of multiple effects of Gypsum fibrosum in makyokansekito. Japan J. Pharmacog., 60, 59–67 (2006).
• 3) Okamura N, Miki H, Orii H, Masaoka Y, Yamashita S, Kobayashi H, Yagi A. Simultaneous high-performance liquid chromatographic determination of puerarin, daidzin, paeoniflorin, liquiritin, cinnamic acid, cinnamaldehyde and glycyrrhizin in Kampo medicines. J. Pharm. Biomed. Anal., 19, 603–612 (1999).
• 4) Kisa K, Sasaki K, Yamauchi K, Kuwano S. Potentiating effect of sennoside C on purgative activity of sennoside A in mice. Planta Med., 42, 302–303 (1981).
• 5) Miyoshi A, Masamune O, Fukutomi H, Mori H, Miwa T, Kojima K, Aono M, Nakajima M. The clinical effect of TSUMURA daiokanzoto extract granules for ethical use (TJ-84) by double blind test against the constipation. Gastroenterology, 18, 299–312 (1994).

Terms in the title (5)： マウス ,  ダイオウ ,  センノシドA ,  下剤 ,  レイン