Art

J-GLOBAL ID：201302270872973275   Reference number：13A0077912

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin

TFE3はミオゲニンの遺伝子発現のダウンレギュレーションを通じてC2C12細胞における筋芽細胞分化を阻害する

Author (19)： NAKA Ayano (Doctoral Program of Sports Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba, 1-1-1 ...) ,  NAKA Ayano (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  IIDA Kaoruko Tada (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  IIDA Kaoruko Tada (Dep. of Applied Nutrition, Graduate School of Humanities and Sciences, Ochanomizu Univ., 2-1-1 Otsuka, Bunkyo, Tokyo ...) ,  NAKAGAWA Yoshimi (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  IWASAKI Hitoshi (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  TAKEUCHI Yoshinori (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  SATOH Aoi (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  MATSUZAKA Takashi (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  ISHII Kiyo-aki (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  KOBAYASHI Kazuto (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  YATOH Shigeru (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  SHIMADA Masako (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  YAHAGI Naoya (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  SUZUKI Hiroaki (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  SONE Hirohito (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  YAMADA Nobuhiro (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...) ,  SHIMANO Hitoshi (Doctoral Program of Sports Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba, 1-1-1 ...) ,  SHIMANO Hitoshi (Dep. of Internal Medicine (Endocrinology and Metabolism), Fac. of Medicine, Univ. of Tsukuba, 1-1-1 Tennodai ...)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 430  Issue： 2  Page： 664-669  Publication year： Jan. 11, 2013 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *transcription factor ,  *DNA binding protein ,  *gene expression ,  Down-Regulation ,  *cultured cell ,  myoblast ,  *Cell Differentiation ,  osteoclast ,  Melanocytes ,  malignant disease ,  metabolic regulation ,  liver ,  skeletal muscle ,  laboratory animal ,  Adenoviridae ,  muscle ,  *differentiation (biology) ,  gene targetting ,  RNA interference ,  genetic technique ,  analysis ,  promoter (genetics) ,  bioassay ,  emission spectrometry ,  luciferase ,  reporter gene ,  gel electrophoresis ,  insulin ,  *C2C12 cell ,  Promoter analysis ,  *Myogenin ,  luciferase assay ,  overexpression ,  metabolic effects ,  *Transcription Factor 3 ,  Models, Animal ,  MyoD Protein ,  Gene Knockdown Technique ,  bHLH ,  Cell Line ,  Electrophoretic Mobility Shift Assay ,  *molecular genetic phenomenon ,  *developmental physiology ,  Biliary Tract ,  microorganism ,  animal virus ,  Heredity ,  hypoglycemic drug ,  metabolic drug ,  carbohydrate metabolic drug ,  drug
Semi thesaurus term： insulin ,  MyoD ,  RNA Interference ,  Adenovirus ,  knockdown ,  bHLH ,  Cell Line ,  electrophoretic mobility shift assay

JST classification (4)： Gene expression  (EC02040Q) ,  Proteins and peptides in general  (EB03010N) ,  Nucleic acids in general  (EB04010U) ,  Cell physiology in general  (EF02010S)

Terms in the title (8)： TFE3 ,  ミオゲニン ,  遺伝子発現 ,  ダウンレギュレーション ,  C2C12細胞 ,  筋芽細胞 ,  分化 ,  阻害