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J-GLOBAL ID：201302275939344105   Reference number：13A0619378

Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression

神経疾患:RAC1のエピジェネティックな調節はストレス障害およびうつ病でシナプスのリモデリングを引き起こす

Author (18)： GOLDEN Sam A (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  CHRISTOFFEL Daniel J (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  HESHMATI Mitra (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  HODES Georgia E (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  MAGIDA Jane (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  DAVIS Keithara (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  CAHILL Michael E (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  DIAS Caroline (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  RIBEIRO Efrain (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  KENNEDY Pamela J (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  ROBISON Alfred J (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  GONZALEZ-MAESO Javier (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  RUSSO Scott J (Graduate School of Biomedical Sci. at the Icahn School of Medicine at Mount Sinai, New York, USA) ,  ABLES Jessica L (Rockefeller Univ., New York, USA) ,  NEVE Rachael L (Massachusetts Inst. of Technol., Massachusetts, USA) ,  TURECKI Gustavo (McGill Univ., Quebec, CAN) ,  GHOSE Subroto (Univ. Texas Southwestern Medical Center, Texas, USA) ,  TAMMINGA Carol A (Univ. Texas Southwestern Medical Center, Texas, USA)
Material： Nature Medicine  (Nat Med)
Volume： 19  Issue： 3  Page： 337-344  Publication year： Mar. 2013 
JST Material Number： W0636A  ISSN： 1078-8956  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *nervous system disease ,  Rho protein ,  *genetic regulation ,  mental disorder ,  depression(disease) ,  nerve regeneration ,  synapse ,  *neurophysiology ,  chromatin ,  mouse(animal) ,  actin binding protein ,  *Neuronal Plasticity
Semi thesaurus term： Rac1 ,  *epigenetic regulation ,  *synapse plasticity ,  cofilin

JST classification (3)： Basic neurology  (GN01020W) ,  Research methods in genetics  (EC01020N) ,  Basic psychiatry  (GR01020I)

Terms in the title (9)： 神経疾患 ,  Rac1 ,  エピジェネティック ,  調節 ,  ストレス ,  障害 ,  うつ病 ,  シナプス ,  リモデリング