Art

J-GLOBAL ID：201302276858141834   Reference number：13A0527932

Protective effects of the herbal medicine goshajinkigan in a rat model of non-alcoholic fatty liver disease

非アルコール性脂肪肝病のラットモデルにおける漢方製剤である牛車腎気丸の保護効果

Author (6)： HIROTANI Yoshihiko (Lab. of Clinical Pharmaceutics, Fac. of Pharmacy, Osaka Ohatani Univ., 3-11-1 Nishikiorikita, Tondabayashi Osaka ...) ,  DOI Ayae (Lab. of Clinical Pharmaceutics, Fac. of Pharmacy, Osaka Ohatani Univ., 3-11-1 Nishikiorikita, Tondabayashi Osaka ...) ,  TAKAHASHI Tomoki (Lab. of Clinical Pharmaceutics, Fac. of Pharmacy, Osaka Ohatani Univ., 3-11-1 Nishikiorikita, Tondabayashi Osaka ...) ,  UMEZAWA Hanako (Lab. of Clinical Pharmaceutics, Fac. of Pharmacy, Osaka Ohatani Univ., 3-11-1 Nishikiorikita, Tondabayashi Osaka ...) ,  URASHIMA Yoko (Lab. of Clinical Pharmaceutics, Fac. of Pharmacy, Osaka Ohatani Univ., 3-11-1 Nishikiorikita, Tondabayashi Osaka ...) ,  MYOTOKU Mitiaki (Lab. of Clinical Pharmaceutics, Fac. of Pharmacy, Osaka Ohatani Univ., 3-11-1 Nishikiorikita, Tondabayashi Osaka ...)
Material： Biomedical Research  (Biomed Res)
Volume： 33  Issue： 6  Page： 373-376 (J-STAGE)  Publication year： 2012 
JST Material Number： Z0236B  ISSN： 0388-6107  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： liver disease ,...
Semi thesaurus term： 非アルコール性脂肪肝病 ,...

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JST classification (1)： Basic research of pharmacology of crude drugs  (GX06020J)

Reference (12)：

• 1. Bugianesi E, Leone N, Vanni E, Marchesini G, Brunello F, Carucci P, Musso A, De Paolis P, Capussotti L, Salizzoni M and Rizzetto M (2002) Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 123, 134-140.
• 2. Hirotani Y, Ikeda K and Myotoku M (2009) Effects of the herbal medicine Goshajinki-gan on sucrose-rich diet-induced hypertriglyceridemia in rats. J Trad Med 26, 187-193.
• 3. Hirotani Y, Doi A, Ikeda K, Kato R, Ijiri Y, Tanaka K and Myotoku M (2011) Effects of Gosha-jinki-gan (Chinese herbal medicine: Niu-Che-Sen-Qi-Wan) on hyper-insulinemia induced in rats fed a sucrose-rich diet. Drug Discoveries Ther 5, 181-184.
• 4. Hu X, Sato J, Oshida Y, Xu M, Bajotto G and Sato Y (2003) Effects of Gosha-jinki-gan (Chinese herbal medicine: Niu-Che-Sen-Qi-Wan) on insulin resistance in streptozotocininduced diabetes rats. Diabetes Res Clin Pract 59, 103-111.
• 5. Madan K, Bhardwaj P, Thareja S, Gupta SD and Saraya A (2006) Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD). J Clin Gastroenterol 40, 930-935.

Terms in the title (6)： 非アルコール性脂肪肝 ,  ラット ,  モデル ,  漢方製剤 ,  牛車腎気丸 ,  保護効果