Art

J-GLOBAL ID：201302283870721982   Reference number：13A0012012

A Novel Mammalian ER-located J-protein, DNAJB14, Can Accelerate ERAD of Misfolded Membrane Proteins

哺乳類ER局在新規J蛋白質,DNAJB14はミスフォールド膜蛋白質のERADを加速できる

Author (7)： SOPHA Pattarawut (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.) ,  KADOKURA Hiroshi (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.) ,  YAMAMOTO Yo-hei (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.) ,  TAKEUCHI Masato (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.) ,  SAITO Michiko (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.) ,  TSURU Akio (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.) ,  KOHNO Kenji (Lab. of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Inst. of Sci. and Technol.)
Material： Cell Structure and Function (Web)  (Cell Struct Funct (Web))
Volume： 37  Issue： 2  Page： 177-187 (J-STAGE)  Publication year： 2012 
JST Material Number： U0126A  ISSN： 1347-3700  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： folded structure ,...
Semi thesaurus term： misfolding ,...

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JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Substance index (1)： MG-132

Reference (23)：

• Goldberg, A.L. and St. John, A.C. 1976. Intracellular protein degradation in mammalian and bacterial cells: Part 2. Annu. Rev. Biochem., 45: 747窶錀803.
• Grove, D.E., Fan, C.Y., Ren, H.Y., and Cyr, D.M. 2011. The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRΔF508. Mol. Biol. Cell, 22: 301窶錀314.
• Hageman, J. and Kampinga, H.H. 2009. Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/ HSPA/DNAJ expression library. Cell Stress Chaperon., 14: 1窶錀21.
• Hebert, D.N. and Molinari, M. 2007. In and out of the ER: protein folding, quality control, degradation, and related human diseases. Physiol. Rev., 87: 1377窶錀1408.
• Hegde, R.S. and Ploegh, H.L. 2010. Quality and quantity control at the endoplasmic reticulum. Curr. Opin. Cell Biol., 22: 437窶錀446.

Terms in the title (6)： 哺乳類 ,  Er ,  蛋白質 ,  膜蛋白質 ,  ERAD ,  加速