Art

J-GLOBAL ID：201302288952226701   Reference number：13A0831803

UV-mediated downregulation of the endocytic collagen receptor, Endo180, contributes to accumulation of extracellular collagen fragments in photoaged skin

エンドサイトーシスコラーゲン受容体Endo180のUVを媒介したダウンレギュレーションは紫外線老化した皮膚における細胞外コラーゲンフラグメントの蓄積に貢献する

Author (5)： TANG Stefanie (Res. & Dev., Beiersdorf AG, Unnastr. 48, 20245 Hamburg, DEU) ,  LUCIUS Ralph (Dep. of Anatomy, Olshausenstr. 40, Univ. of Kiel, 24098 Kiel, DEU) ,  WENCK Horst (Res. & Dev., Beiersdorf AG, Unnastr. 48, 20245 Hamburg, DEU) ,  GALLINAT Stefan (Res. & Dev., Beiersdorf AG, Unnastr. 48, 20245 Hamburg, DEU) ,  WEISE Julia M. (Res. & Dev., Beiersdorf AG, Unnastr. 48, 20245 Hamburg, DEU)
Material： Journal of Dermatological Science  (J Dermatol Sci)
Volume： 70  Issue： 1  Page： 42-48  Publication year： Apr. 2013 
JST Material Number： W1280A  ISSN： 0923-1811  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： cell adhesion receptor ,...
Semi thesaurus term： Receptors, Collagen ,...

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JST classification (1)： Basic dermatology  (GF01020Y)

Reference (37)：

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• Varani, J., Schuger, L., Dame, M.K., Leonard, C., Fligiel, S.E., Kang, S. et al, Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin. J Invest Dermatol. 2004;122:1471-9.
• Varani, J., Spearman, D., Perone, P., Fligiel, S.E., Datta, S.C., Wang, Z.Q. et al, Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro. Am J Pathol. 2001;158:931-42.

Terms in the title (7)： エンドサイトーシス ,  コラーゲン受容体 ,  ダウンレギュレーション ,  紫外線 ,  老化 ,  皮膚 ,  蓄積