Art

J-GLOBAL ID：201302289145163638   Reference number：13A1023334

Transient Helical Structure during PI3K and Fyn SH3 Domain Folding

PI3KとFyn SH3ドメイン折畳み間の過渡的螺旋構造

Author (8)： MATSUMURA Yoshitaka (Kansai Medical Univ., Hirakata, JPN) ,  SHINJO Masaji (Kansai Medical Univ., Hirakata, JPN) ,  KIM Seung Joong (Univ. Illinois, Illinois, USA) ,  OKISHIO Nobuyuki (Japanese Red Cross Hokkaido Blood Center, Sapporo, JPN) ,  GRUEBELE Martin (Univ. Illinois, Illinois, USA) ,  KIHARA Hiroshi (Kansai Medical Univ., Hirakata, JPN) ,  KIHARA Hiroshi (Ritsumeikan Univ., Shiga, JPN) ,  KIHARA Hiroshi (Nagoya Univ., Nagoya, JPN)
Material： Journal of Physical Chemistry B  (Journal of Physical Chemistry B. Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter)
Volume： 117  Issue： 17  Page： 4836-4843  Publication year： May. 02, 2013 
JST Material Number： W0921A  ISSN： 1520-6106  CODEN： JPCBFK  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *binding site ,  *folded structure ,  *Phosphatidylinositol 3-Kinase ,  *non-receptor tyrosine kinase ,  beta-structure ,  helix structure ,  transient phenomenon ,  temperature dependence ,  pressure effect ,  repressor ,  mutant ,  robustness ,  Src protein ,  compactness ,  circular dichroism ,  small angle X-ray scattering ,  stopped flow method ,  conformational transition ,  force field ,  Computer Simulation ,  molecular dynamics ,  amino acid residue ,  locality ,  nucleation ,  Amino Acid Sequence ,  Fyn ,  Fyn protein ,  SH3 domain ,  alpha helix ,  Molecular Dynamics Simulation ,  misfolding ,  computer application ,  utilization
Semi thesaurus term： PI-3K ,  beta sheet structure ,  Repressor Proteins ,  pressure dependence ,  transient ,  Protein misfolding ,  helical structure

JST classification (1)： Molecular structure  (EB03020Y)

Terms in the title (5)： PI3K ,  Fyn ,  SH3ドメイン ,  折畳み ,  螺旋構造