Art

J-GLOBAL ID：201302295548255699   Reference number：13A1002748

Dipeptidyl Peptidase-4 Inhibitor, Sitagliptin, Improves Endothelial Dysfunction in Association With Its Anti-Inflammatory Effects in Patients With Coronary Artery Disease and Uncontrolled Diabetes

ジペプチジルペプチダーゼ-4阻害剤シタグリプチンは冠動脈疾患及びコントロール不良の糖尿病を有する患者において抗炎症作用とともに内皮機能障害を改善する

Author (16)： MATSUBARA Junichi (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  MATSUBARA Junichi (Dep. of Cardiovascular Clinical and Translational Res., Kumamoto Univ. Hospital) ,  SUGIYAMA Seigo (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  AKIYAMA Eiichi (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  IWASHITA Satomi (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  KUROKAWA Hirofumi (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  OHBA Keisuke (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  MAEDA Hirofumi (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  FUJISUE Koichiro (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  YAMAMOTO Eiichiro (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  KAIKITA Koichi (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  HOKIMOTO Seiji (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.) ,  HOKIMOTO Seiji (Dep. of Interventional Cardiology, Kumamoto Univ. Hospital) ,  JINNOUCHI Hideaki (Dep. of Preventive Cardiology, Kumamoto Univ. Hospital) ,  JINNOUCHI Hideaki (Jinnouchi Hospital) ,  OGAWA Hisao (Dep. of Cardiovascular Medicine, Fac. of Life Sciences, Graduate School of Medical Sciences, Kumamoto Univ.)
Material： Circulation Journal  (Circ J)
Volume： 77  Issue： 5  Page： 1337-1344 (J-STAGE)  Publication year： 2013 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *vascular endothelial function

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JST classification (1)： Drug therapy(=pharmacotherapy)for cardiovascular system diseases  (GJ05020M)

Substance index (1)： Sitagliptin

Reference (30)：

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• LIBBY, P. Inflammation in atherosclerosis. Nature. 2002, 420, 868-874
• LI, AC. The macrophage foam cell as a target for therapeutic intervention. Nat Med. 2002, 8, 1235-1242

Terms in the title (9)： ジペプチジルペプチダーゼ ,  阻害剤 ,  シタグリプチン ,  冠動脈疾患 ,  コントロール ,  糖尿病 ,  患者 ,  抗炎症作用 ,  内皮機能障害