Art

J-GLOBAL ID：201302296308744419   Reference number：13A0994659

Prostaglandin E₂-Induced Cell Death is Mediated by Activation of EP2 Receptors in Motor Neuron-like NSC-34 Cells

プロスタグランジンE₂誘発細胞死は,運動ニューロン様NSC-34細胞においてEP2受容体の活性化によって媒介される

Author (9)： MIYAGISHI Hiroko (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  KOSUGE Yasuhiro (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  YONEOKA Yuki (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  OZONE Maiko (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  ENDO Manami (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  OSADA Nobuhiro (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  ISHIGE Kumiko (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN) ,  KUSAMA-EGUCHI Kuniko (Lab. of Biochemistry, School of Pharmacy, Nihon Univ., JPN) ,  ITO Yoshihisa (Lab. of Pharmacology, School of Pharmacy, Nihon Univ., JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 121  Issue： 4  Page： 347-350 (J-STAGE)  Publication year： 2013 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *prostaglandin ,...
Semi thesaurus term： NSC-34 cell ,...

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JST classification (1)： Other hormones of verterbrates  (EB08070K)

Substance index (3)： Dinoprostone ,  Sulprostone ,  Butaprost

Reference (15)：

• ILZECKA, J. Prostaglandin E2 is increased in amyotrophic lateral sclerosis patients. Acta Neurol Scand. 2003, 108, 125-129
• KLIVENYI, P. Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem. 2004, 88, 576-582
• MIYAGISHI, H. Expression of microsomal prostaglandin E synthase-1 in the spinal cord in a transgenic mouse model of amyotrophic lateral sclerosis. J Pharmacol Sci. 2012, 118, 225-236
• TAKADERA, T. Prostaglandin E_2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons. Neurochem Int. 2004, 45, 713-719
• MCCULLOUGH, L. Neuroprotective function of the PGE_2 EP2 receptor in cerebral ischemia. J Neurosci. 2004, 24, 257-268

Terms in the title (7)： プロスタグランジンE2 ,  誘発 ,  細胞死 ,  運動ニューロン ,  NSC-34細胞 ,  EP2受容体 ,  活性化