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J-GLOBAL ID:201302299743477448   Reference number:13A1888387

A unique mouse model for investigating the properties of amyotrophic lateral sclerosis-associated protein TDP-43, by in utero electroporation

子宮内電気穿孔法による筋萎縮性側索硬化症関連蛋白質TDP-43の特徴を調査するための独自マウスモデル
Author (9):
Material:
Volume: 77  Issue:Page: 234-241  Publication year: Dec. 2013 
JST Material Number: D0210C  ISSN: 0168-0102  Document type: Article
Article type: 原著論文  Country of issue: Netherlands (NLD)  Language: ENGLISH (EN)
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Basic neurology  ,  Central nervous system  ,  Laboratry organisms 
Reference (31):
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  • Arai, T., Hasegawa, M., Nonoka, T., Kametani, F., Yamashita, M., Hosokawa, M., Niizato, K., Tsuchiya, K., Kobayashi, Z., Ikeda, K., Yoshida, M., Onaya, M., Fujishiro, H., Akiyama, H., 2010. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy. Neuropathology: Official Journal of the Japanese Society of Neuropathology 30(2), 170-181.
  • Arnold, E.S., Ling, S.C., Huelga, S.C., Lagier-Tourenne, C., Polymenidou, M., Ditsworth, D., Kordasiewicz, H.B., McAlonis-Downes, M., Platoshyn, O., Parone, P.A., Da Cruz, S., Clutario, K.M., Swing, D., Tessarollo, L, Marsala, M., Shaw, C.E., Yeo, G.W., Cleveland, D.W., 2013. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America 110 (8), E736-E745.
  • Baloh, R.H., 2011. TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. The FEBS Journal 278 (19), 3539-3549.
  • Bao, Y.P., Cook, L.J., O'Donovan, D., Uyama, E., Rubinsztein, D.C., 2002. Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy. The Journal of Biological Chemistry 277 (14), 12263-12269.
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