J-GLOBAL ID:201401001067568642   Update date: Jul. 04, 2021

Harada Hiroshi

ハラダ ヒロシ | Harada Hiroshi
Affiliation and department:
Research field  (1): Tumor biology
Papers (138):
  • Suwa T, Kobayashi M, Nam JM, Harada H. Tumor microenvironment and radioresistance. Experimental & Molecular Medicine. 2021. in press
  • Uba T, Matsuo Y, Sumi C, Shoji C, Nishi K, Kusunoki M, Harada H, Kimura H, Bono H, Hirota K. Polysulfide inhibits hypoxia-inducible factor activation in a mitochondria-dependent manner. Mitochondrion. 2021. in press
  • Huo W, Miki K, Tokunaga D, Mu H, Oe M, Harada H, Ohe K. Dual-stimuli-responsive probes for detection of ovarian cancer cells and quantification of both pH and enzyme activity. Bull Chem Soc Jpn. 2021. in press
  • Shirai Y, Chow CCT, Kambe G, Suwa T, Kobayashi M, Takahashi I, Harada H, Nam JM. An Overview of the Recent Development of Anticancer Agents Targeting the HIF-1 Transcription Factor. Cancers. 2021. 13. 2813
  • Masahiro Maruoka, Panpan Zhang, Hiromi Mori, Eiichi Imanishi, Daniel M. Packwood, Hiroshi Harada, Hidetaka Kosako, Jun Suzuki. Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane. Molecular Cell. 2021. 81. 7. 1397-1410.e9
MISC (13):
Patents (7):
  • がんを治療するための医薬組成物
  • がんを治療するための医薬組成物
  • 新規抗腫瘍剤及び新規抗腫瘍剤のスクリーニング方法
  • 病態の状態をリアルタイムで観察可能なモデル動物とそれを可能にする遺伝子構築物及びその使用
  • Polypeptide unstablizing protein in cells under aerobic conditions and DNA encoding the same
Books (3):
  • Molecularly based Chemoradiotherapy and High-Precision Radiotherapy. Tan D, Lynch H (eds).
    Lippincott Williams & Milkins. 2012
  • Protein Transduction Domain-mediated Delivery of Anti-cancer Drugs and Proteins. Lu Y and Mahato RI (eds). Pharmaceutical Perspectives of Cancer Therapeutics.
    Springer 2009
  • Combination of Antimetabolites and Ionizing Radiation. Medical Radiology: Radiation Oncology, Multimodal Concepts for Integration of Cytotoxic Drugs.
    Springer 2006
Lectures and oral presentations  (137):
  • 低酸素バイオロジーで迫る「がんの悪性形質と治療抵抗性」
    (リプロセル学術講演会 2021)
  • Functional and mechanistic linkage betweenp53-deficiency to HIF-1-mediated hypoxia signaling in cancers.
    (The 43rd. MBSJ 2020)
  • 低酸素と放射線の関わり
    (第10回日本放射線腫瘍学会(JASTRO)放射線生物学セミナー 2020)
  • 放射線腫瘍学における低酸素バイオロジー.
    (第49回. 京都放射線腫瘍研究会 2020)
  • A link between activation of HIF-1 and defect in p53 in malignantprogression of cancers.
    (International Seminar on Stress Medicine and PrecisionHealthcare; from Hypoxia and DNA Damage Response to Therapeutic Intervention 2019)
Professional career (1):
  • 博士(理学) (名古屋大学)
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