Liu Li

リュウリ | Liu Li

Affiliation and department：
Job title： Specially Appointed Professor

Research field (3)： Biomedical engineering , Biomaterials , Cardiovascular surgery

Research theme for competitive and other funds (19)：

2022 - 2031 フォトニクス生命工学研究開発拠点
2022 - 2025 hiPSC Derived Mesenchymal stem cells Tissue Enhance Therapeutic Effects of Cardiomyocytes and MSC Tissue Transplantation in Myocardial Infarction Model
2022 - 2025 Cardiac electrophysiology evaluation system for improved drug assessment
2022 - 2025 心筋組織機能評価用新規デバイスを用いた医薬品安全・有効性評価
2020 - 2023 Creating "3D mini heart" for transplantation of heart failure

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Papers (65)：

Junjun Li, Menglu Li, Yasunori Nawa, Yuting Liu, Kazuki Bando, Ying Hua, Lifu Sun, Satoshi Fujita, Yoshiki Sawa, Katsumasa Fujita, et al. Label-Free Raman Spectroscopy for Assessing Purity and Maturation of hiPSC-Derived Cardiac Tissue. Analytical Chemistry. 2024. 96. 39. 15765-15772
Jingbo Zhang, Junjun Li, Xiang Qu, Yuting Liu, Lifu Sun, Akima Harada, Ying Hua, Nagako Sougawa, Akiko Tabata, Li Liu, et al. Development of composite functional tissue sheets using hiPSC-CMs and hADSCs to improve the cardiac function after myocardial infarction. Bioactive Materials. 2024. 37. 533-548
Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba, et al. Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment. iScience. 2024. 27. 2. 108992-108992
Jingbo Zhang, Junjun Li, Xiang Qu, Yuting Liu, Akima Harada, Ying Hua, Noriko Yoshida, Masako Ishida, Akiko Tabata, Lifu Sun, et al. Development of a thick and functional human adipose-derived stem cell tissue sheet for myocardial infarction repair in rat hearts. Stem cell research & therapy. 2023. 14. 1. 380-380
Akihiro Hashida, Taro Nakazato, Toshimasa Uemura, Li Liu, Shigeru Miyagawa, Yoshiki Sawa, Masahiro Kino-oka. Effect of morphological change on the maturation of human induced pluripotent stem cell-derived cardiac tissue in rotating flow culture. Regenerative Therapy. 2023. 24. 479-488

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MISC (31)：

植村寿公, 植村寿公, 橋田礼博, 中里太郎, LIU Li, 宮川繁, 澤芳樹, 紀ノ岡正博. 回転浮遊培養によるヒトiPS細胞由来心筋組織の成熟化メカニズムの解明. 日本再生医療学会総会(Web). 2024. 23rd
Kazuhiro Aiba, Liu Li, Kensuke Kato, Norio Nakatsuji. SCAD-MT Cardiomyocyte: Human Pluripotent Stem Cell-Derived Cardiomyocyte Micro-tissues That Show Maturation and Functional Stability Promoted by Using Aligned Nanofibers. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017. 88. 235-235
Li Liu. Low cell-matrix adhesion microenvironment promote maintain of high-pluripotency state stem cells. 10 Years of iPSCs Cell Symposium. 2016
Li Liu. Engineered anisotropic and 3-demensional hiPS-derived cardiac tissue-like construct for drug assessment and cardiac disease repairing. 2016
Li Liu. Creating functional anisotropic and 3D tissue-like construct using induced pluripotent stem cell-derived cardiomyocytes. CiRA/ISSCR 2016 International Symposia. 2016

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Patents (19)：

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Books (1)：

Fabrication of Thick and Anisotropic Cardiac Tissue on Nanofibrous Substrate for Repairing Infarcted Myocardium
Humana, New York, NY

Lectures and oral presentations (15)：

Human iPSC derived cardiac tissue matured by spontaneous traveling waves for improved drug assessment.
(American Heart Association Scientific Session,)
Micro-/Nanofibrous Matrices for pluripotent stem cell and cardiac tissue transplantation
(MU-OU joint Symposium 2021)
機能性iPS細胞由来心筋組織を用いた心不全再生医療法の開発
ナノファイバーを用いたヒトiPS細胞由来心筋組織の構築及び再生医療への応用
(2020)
Circulating traveling waves enhance the maturation of hipsc-derived cardiomyocytes in self-organized tissue ring
(the 8th Meeting of the International Federation for Artificial Organs. 2019)

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