Rchr
J-GLOBAL ID:201401007076551297   Update date: Sep. 01, 2020

Takumi Ueda

ウエダ タクミ | Takumi Ueda
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/20451859.ja.html
Research field  (1): Pharmaceuticals - analytical and physicochemistry
Research keywords  (29): NMR ,  膜タンパク質 ,  転移交差飽和法 ,  タンパク質-タンパク質相互作用 ,  構造生物学 ,  光合成明反応 ,  photosynthesis ,  CCR1 ,  オピオイド受容体 ,  生化学 ,  アドレナリン受容体 ,  交差飽和法 ,  光合成名反応 ,  電子移動反応 ,  フェレドキシン ,  Membrane protein ,  ケモカイン受容体 ,  protein-protein interaction ,  electron transfer ,  過渡的相互作用 ,  マルチドメイン蛋白質 ,  膜蛋白質 ,  GPCR ,  Segmental labeling ,  核磁気共鳴法 ,  transferred cross saturation ,  循環的電子伝達 ,  光化学系I ,  Protein Trans-Splicing
Research theme for competitive and other funds  (6):
  • 2013 - 2015 GPCRの、バイアスを含むシグナル制御機構の構造生物学的解明
  • 2013 - 2014 医学上重要なGPCRのシグナル制御機構の構造生物学的解明
  • 2011 - 2012 GPCRのシグナル伝達機構の構造生物学的解明
  • 2011 - 2012 二成分制御系における連鎖的シグナル伝達機構の構造生物学的解明
  • 2008 - 2009 Structural elucidation of the efficient electron transport between photosynthetic membrane proteins and electron carrier
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Papers (30):
  • Ichio Shimada, Takumi Ueda, Yutaka Kofuku, Matthew T Eddy, Kurt Wüthrich. GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures. Nature reviews. Drug discovery. 2019. 18. 1. 59-82
  • Yutaro Shiraishi, Mei Natsume, Yutaka Kofuku, Shunsuke Imai, Kunio Nakata, Toshimi Mizukoshi, Takumi Ueda, Hideo Iwaï, Ichio Shimada. Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR. Nature Communications. 2018. 9. 1. 194
  • Yutaka Kofuku, Tomoki Yokomizo, Shunsuke Imai, Yutaro Shiraishi, Mei Natsume, Hiroaki Itoh, Masayuki Inoue, Kunio Nakata, Shunsuke Igarashi, Hideyuki Yamaguchi, et al. Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system. Journal of biomolecular NMR. 2018. 71. 3. 185-192
  • Yousuke Takaoka, Shohei Uchinomiya, Daichi Kobayashi, Masataka Endo, Takahiro Hayashi, Yoshiaki Fukuyama, Haruko Hayasaka, Masayuki Miyasaka, Takumi Ueda, Ichio Shimada, et al. Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells. Chem. 2018. 4. 6. 1451-1464
  • Yuichi Minato, Takumi Ueda, Asako Machiyama, Hideo Iwai, Ichio Shimada. Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR. SCIENTIFIC REPORTS. 2017. 7. 1. 16462
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MISC (99):
Professional career (1):
  • 薬学博士 (東京大学大学院薬学系研究科)
Work history (1):
  • 2007/01 - 現在 The University of Tokyo
Association Membership(s) (3):
THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN
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