Rchr
J-GLOBAL ID：201401015214502203
Update date: Nov. 22, 2024
Sasai Miwa
ササイ ミワ | Sasai Miwa
Affiliation and department：
Job title：
Associate Professor
Homepage URL (1)：
http://kaken.nii.ac.jp/d/r/30631551.ja.html
Research field (1)：
Immunology
Research keywords (2)：
Parasitology
, Innate Immunity
Research theme for competitive and other funds (4)：
- 2018 - 2022 Pathogenic and genetic analysis of Toxoplasma by Japan, China and South Korea
- 2018 - 2022 The role of Atg family members on autophagy independent pathway
- 2014 - 2016 The regulation of cytokine production by phospholipid on MVB
- 2012 - 2014 Mechanism of antiviral responses by type-II Interferon
Papers (71)：
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Masaaki Okamoto, Ayumi Kuratani, Daisuke Okuzaki, Naganori Kamiyama, Takashi Kobayashi, Miwa Sasai, Masahiro Yamamoto. IFN-γ-induced Th1-Treg polarization in inflamed brains limits exacerbation of experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 48. e2401692121
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Ayumi Kuratani, Masaaki Okamoto, Kazuki Kishida, Daisuke Okuzaki, Miwa Sasai, Shimon Sakaguchi, Hisashi Arase, Masahiro Yamamoto. Platelet factor 4-induced TH1-Treg polarization suppresses antitumor immunity. Science (New York, N.Y.). 2024. 386. 6724. eadn8608
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Yuki Nakayama, Fumiaki Ihara, Daisuke Okuzaki, Yoshifumi Nishikawa, Miwa Sasai, Masahiro Yamamoto. Toxoplasma GRA15 expression on dendritic cells inhibits B cell differentiation and antibody production. Parasitology international. 2024. 102995-102995
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Yuta Tachibana, Miwa Sasai, Masahiro Yamamoto. CRISPR screens identify genes essential for in vivo virulence among proteins of hyperLOPIT-unassigned subcellular localization in Toxoplasma. mBio. 2024. 15. 9. e0172824
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Masaaki Okamoto, Ayumi Kuratani, Daisuke Okuzaki, Naganori Kamiyama, Takashi Kobayashi, Miwa Sasai, Masahiro Yamamoto. Tff1-expressing Tregs in lung prevent exacerbation of Bleomycin-induced pulmonary fibrosis. Frontiers in immunology. 2024. 15. 1440918-1440918
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MISC (3)：
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Miwa Sasai, Masahiro Yamamoto. Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. CYTOKINE. 2017. 100. 29-29
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Payal Mehta, Jill Henault, Jennifer Martinez, Jeffery Riggs, Jane Tian, Lorraine Clarke, Miwa Sasai, Eicke Latz, Melanie Brinkmann, Akiko Lwasaki, et al. LC3-associated phagocytosis mediates IFN-alpha secretion in response to DNA-immune complexes. JOURNAL OF IMMUNOLOGY. 2014. 192
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Michal Tal, Miwa Sasai, Akiko Iwasaki. RLR signaling is amplified by reactive oxygen species and dysfunctions in autophagy. JOURNAL OF IMMUNOLOGY. 2011. 186
Books (2)：
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マウス表現型解析スタンダード
羊土社 2016 ISBN:9784758101981
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インターフェロンγ誘導性GTPaseとトキソプラズマ感染防御
医学のあゆみ 2014
Lectures and oral presentations (30)：
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Uncovering a novel role of PLCb in selectively mediating TCR signaling in CD8+ but not CD4+ T cells
(第43回 分子生物学会・ワークショップ (口頭) 2020)
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PLCβ plays an important role in CD8 T cell-mediated host defense against Toxoplasma gondii
(第46回 日本免疫学会学術集会 2017)
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Role of GABARAP subfamily in the regulation of non-canonical inflammasome activation
(第46回 日本免疫学会学術集会 2017)
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Critical roles of GABARAPs on interferon-mediated cell-autonomous immune responses against T. gondii infection
(第46回 日本免疫学会学術集会 2017)
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Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases
(CYTOKINE2017 2017)
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Work history (5)：
- 2017/08 - 現在 Osaka University Research Institute for Microbial Diseases
- 2012/04 - 2017/07 Osaka University Research Institute for Microbial Diseases
- 2007/04 - 2012/03 Yale University Immunobiology
- 2009/04 - 2011/03 日本学術振興会 海外特別研究員
- 2005/04 - 2007/03 日本学術振興会 特別研究員
Awards (5)：
- 2018/11 - 大阪大学 大阪大学賞
- 2018/04 - 文部科学省 文部科学大臣表彰・若手科学者賞
- 2018/04 - 文部科学省 若手科学者賞 細胞内小胞輸送を介した病原体排除機構に関する研究
- 2017/12 - Japanese Society for Immunology(JSI) 2017 JSI Young Investigator Award
- 2017/12 - Japanese Society for Immunology (JSI) JSI Young Investigator Award
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