Nakashima Ichiro

ナカシマイチロウ | Nakashima Ichiro

Affiliation and department：
Job title：教授
Homepage URL (2)： https://twitter.com/ichi580 , https://scholar.google.com/citations?user=9rCdYCIAAAAJ&hl=ja&oi=ao

Research field (1)： Neurology

Research keywords (30)：多発性硬化症 , 視神経脊髄炎 , 脳神経疾患 , 自己抗体 , オリゴクローナルバンド , ELISA , 抗アクアポリン4抗体 , SELDI-TOF , 末梢血単核球 , サイトカイン , 等電点電気泳動法 , フローサイトメトリー , ファージディスプレイ法 , 視神経脊髄型 , MALDI-TOF , 神経免疫 , IgGサブクラス , ケモカイン , IgGインデックス , SEREX法 , NMO-IgG , 2次元電気泳動 , 免疫抑制剤 , B細胞 , 視神経脊髄型多発性硬化症 , 脱髄疾患 , 視神経脊髄型MS , 通常型MS , デビック病 , プロテインチップ

Research theme for competitive and other funds (27)：

2020 - 2023 Development of detecting assay for anti-myelin oligodendrocyte glycoprotein antibody
2017 - 2020 Development of diagnostic tools and discovery of pathology in anti-MOG antibody associated demyelinating disease
2017 - 2020 Development of diagnostic tools and discovery of pathology in anti-MOG antibody associated demyelinating disease
2013 - 2016 Establishment and analyses of rodent model of optic neuritis in neuromyelitis optics
2013 - 2016 Establishment and analyses of rodent model of optic neuritis in neuromyelitis optics

2010 - 2015 Establishment of a new disease entity as astrocytopathy, and studies on the pathogenesis and treatment for neuromyelitis optica

2009 - 2010 Analyses of B cell in multiple sclerosis

2008 - 2010 Clarification of aquaporin-4 related molecular and cellular pathomechanism in neuromyelitis optica (Devic's disease)

2009 - 2010 Analyses of B cell in multiple sclerosis

2008 - 2010 Clarification of aquaporin-4 related molecular and cellular pathomechanism in neuromyelitis optica (Devic's disease)

2007 - 2009 Optic-spinal multiple sclerosis : clarification of pathogenesis, establishment of new disease entity and treatment

2006 - 2007 A Study of the Regulation of Dendritic Cells and Immunological Memory by Immunoglobulins in Multiple Sclerosis

2005 - 2006 A Study on the Pathogenesis and Therapy of Optic-Spinal Multiple Sclerosis

2005 - 2006 視神経脊髄型多発性硬化症の自己抗原同定

2005 - 2006 A Study on the Pathogenesis and Therapy of Optic-Spinal Multiple Sclerosis

2005 - 2006 視神経脊髄型多発性硬化症の自己抗原同定

2004 - 2005 プロテインチップを用いた多発性硬化症髄液バイオマーカーの検索

2003 - 2004 COMPARATIVE ANALYSIS OF CLINICAL AND MOLECULAR IMMUNOLOGICAL PATHOGENESES IN SUBTYPES OF MULTIPLE SCLEROSIS IN JAPAN

2003 - 2004 DYNAMIC ANALYSIS OF MEMORY T GEELs IN RELAPSE AND CHRONIC PROGRESSION IN THE PATHOGENESIS OF MULTIPLE SCLEROSIS

2003 - 2004 多発性硬化症におけるオリゴクローナルバンドの病因的意義に関する研究

2003 - 2004 COMPARATIVE ANALYSIS OF CLINICAL AND MOLECULAR IMMUNOLOGICAL PATHOGENESES IN SUBTYPES OF MULTIPLE SCLEROSIS IN JAPAN

2003 - 2004 DYNAMIC ANALYSIS OF MEMORY T GEELs IN RELAPSE AND CHRONIC PROGRESSION IN THE PATHOGENESIS OF MULTIPLE SCLEROSIS

2003 - 2004 多発性硬化症におけるオリゴクローナルバンドの病因的意義に関する研究

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Papers (438)：

Mitsuru Watanabe, Noriko Isobe, Masaaki Niino, Ichiro Nakashima, Takuya Matsushita, Yasunari Sakai, Jin Nakahara, Izumi Kawachi, Hirofumi Ochi, Yuji Nakatsuji, et al. Prevalence of, and Disability Due to, Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder in Japan by the Fifth Nationwide Survey. Neurology. 2024. 103. 10
Ichiro Nakashima, Nozomu Tanaka. Employment status of multiple sclerosis patients in Japan. Journal of medical economics. 2024. 1-13
Hiroaki Yokote, Yusei Miyazaki, Juichi Fujimori, Yoichiro Nishida, Shuta Toru, Masaaki Niino, Ichiro Nakashima, Yoshiharu Miura, Takanori Yokota. Slowly expanding lesions are associated with disease activity and gray matter loss in relapse-onset multiple sclerosis. Journal of Neuroimaging. 2024
Kimihiko Kaneko, Hiroshi Kuroda, Yuki Matsumoto, Naohiro Sakamoto, Naoya Yamazaki, Naoki Yamamoto, Shu Umezawa, Chihiro Namatame, Hirohiko Ono, Yoshiki Takai, et al. Different Complement Activation Patterns Following C5 Cleavage in MOGAD and AQP4-IgG+NMOSD. Neurology(R) neuroimmunology & neuroinflammation. 2024. 11. 5. e200293
Hiroaki Yokote, Yusei Miyazaki, Juichi Fujimori, Yoichiro Nishida, Shuta Toru, Masaaki Niino, Ichiro Nakashima, Yoshiharu Miura, Takanori Yokota. Characterization of Japanese multiple sclerosis patients with progression independent of relapse activity: A 2-year multicenter cohort study. Journal of neuroimmunology. 2024. 394. 578407-578407

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MISC (597)：

東野将志, 八木橋崇仁, 小川諒, 石垣あや, 小林理子, 中村正史, 宮澤康一, 藤盛寿一, 中島一郎. 栄養欠乏性視神経症のブータン人女性例. 臨床神経学(Web). 2023. 63. 4
金子仁彦, 黒田宙, 黒田宙, 小野紘彦, 松本勇貴, 松本勇貴, 松本勇貴, 山崎直也, 山本尚輝, 梅澤周, et al. Analysis of CSF complement profile in myelin oligodendrocyte glycoprotein associated disease. 補体. 2023. 60. 1
山下きみか, 石垣あや, 東野将志, 八木橋崇仁, 小川諒, 小林理子, 中村正史, 宮澤康一, 藤盛寿一, 中島一郎. 肺小細胞癌に合併した四肢のしびれと筋力低下をきたした1例. 臨床神経学(Web). 2023. 63. 4
目黒祐子, 萱場文, 宮澤康一, 藤盛寿一, 鈴木潤, 中島一郎. 新型コロナウィルス罹患後のブレインフォグ2例の経験から. 日本神経心理学会学術集会プログラム予稿集. 2023. 47th
此松和俊, 此松和俊, 藤盛寿一, 金子仁彦, 神一敬, 三須建郎, 中島一郎, 中里信和, 青木正志. Myelin oligodendrocyte glycoprotein抗体関連疾患の脳波所見の特徴. 日本神経学会学術大会プログラム・抄録集. 2023. 64th

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Education (2)：

1994 - 1999 東北大学大学院医学(系)研究科
1988 - 1994 Tohoku University Faculty of Medicine School of Medicine

Professional career (1)：

医学博士 (東北大学大学院医学系研究科)

Work history (6)：

2023/04 - 現在 Tohoku Medical and Pharmaceutical University Hospital Vice-president
2023/04 - 現在 Tohoku Medical and Pharmaceutical University Division of Neurology Professor
2017/04 - 2023/03 Tohoku Medical and Pharmaceutical University
2012/11 - 2017/03 Tohoku University
2010/02 - 2012/10 Tohoku University

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Association Membership(s) (7)：

日本小児神経学会 , 日本免疫学会 , 日本神経治療学会 , 日本神経免疫学会 , 日本神経学会 , 日本内科学会 , 日本神経感染症学会

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