Rchr
J-GLOBAL ID：201401019117015042
Update date: Apr. 04, 2024
Ikegami Hiroshi
イケガミ ヒロシ | Ikegami Hiroshi
Affiliation and department：
Homepage URL (1)：
http://kaken.nii.ac.jp/d/r/20221062.ja.html
Research field (1)：
Metabolism and endocrinology
Research keywords (10)：
糖尿病
, 遺伝子
, 多因子疾患
, 遺伝
, 1型糖尿病
, モデル動物
, 自己免疫
, テーラーメード医療
, ゲノム
, HLA
Research theme for competitive and other funds (50)：
- 2022 - 2025 糖尿病患者におけるサルコペニア発症に関与する遺伝因子と分子メカニズムの解明
- 2021 - 2024 2型糖尿病における複合遺伝形質の分割とエピスタシス・エピジェネティクス解析
- 2021 - 2024 Identification and functional analysis of novel type 1 diabetogenic genes in the Japanese population by next-generation sequencing
- 2021 - 2024 膵β細胞機能の完全廃絶を規定する遺伝因子ならびにバイオマーカーの同定と解析
- 2020 - 2023 Exploratory analysis of clinical and molecular markers for sarcopenia in populations with different characteristics, and applied study for the practical use of the markers.
- 2017 - 2022 ICTを活用したDiabetic Kidney Diseaseの成因分類と糖尿病腎症重症化抑制法の構築
- 2018 - 2021 The elucidation of gene-environment interaction network in type 2 diabetes
- 2018 - 2021 Identification of susceptibility genes for type 1 diabetes: whole-exome sequence analysis in rare multiplex families in Japanese
- 2017 - 2020 Mechanism and novel biomarkers for pancreatic beta cell-specific destruction in type 1 diabetes
- 2016 - 2018 1型糖尿病の実態調査、客観的診断基準、日常生活・社会生活に着目した重症度評価の作成に関する研究
- 2015 - 2018 The elucidation of diabetogenic factors and its interaction in type 2 diabetes
- 2015 - 2018 Identification of susceptibility genes for autoimmunity and beta-cell specificity of type 1 diabetes
- 2014 - 2017 Genes related to islet-specific autoimmune destruction and prevention of type 1 diabetes by regulating immune tolerance
- 2014 - 2017 Identification and characterization of susceptible genes to type 1 diabetes using in the clustered family
- 2014 - 2016 難治性膵疾患に関する調査研究
- 2013 - 2016 Elucidation of the control structure of immunity and the onset prevention by the type 1 diabetes mellitus gene analysis
- 2011 - 2015 Genetic analyses of the susceptibility gene for streptozotocin induced diabetes in A/J mice
- 2012 - 2015 The strategy for elucidation of diabetogenic factors:functional partition and reintegrate
- 2012 - 2015 Organ specificity in autoimmune diseases: beta-cells and type 1 diabetes
- 2011 - 2013 Analysis of genetic basis for islet-specific autoimmunity and the applecation to prevention and treatment of type 1 diabetes
- 2011 - 2013 Identification and characterization of susceptibility genes for type 1 diabetes in the major histocompatibility complex
- 2009 - 2011 Identification of the diabetogenic gene and its related genes of high fat diet-induced diabetes by using novel mouse model
- 2009 - 2011 Identification and characterization of susceptibility genes for type 1 diabetes by using syntenic homology between human and mouse
- 2008 - 2010 Identification and functional analysis of common genetic basis between type 1 diabetes and type 2 diabetes.
- 2005 - 2007 Identification of type 2 diabetes genes on chromosome 2 of SMXA-5 mouse.
- 2005 - 2006 Elucidation of susceptibility gene for type 1 diabetes mellitus by integration of functional analysis of recombinant chromosome with bioinformatics
- 2004 - 2006 Functional analysis of susceptibility genes for diabetes: gene-gene and gene-environment interaction
- 2004 - 2004 1型糖尿病遺伝子の機能解析に基づくテーラーメード医療の構築
- 2003 - 2004 Elucidation of susceptibility gene for type 1 diabetes mellitus using comparative chromosome map between human and animal model
- 2003 - 2004 Identification of causative gene for type 2 diabetes in SMXA-5 mouse feeding a high fat diet.
- 2003 - 2003 1型糖尿病遺伝子の機能解析に基づくテーラーメード医療の構築
- 2002 - 2003 ゲノムワイド点突然変異誘発法を用いた新規糖尿病遺伝子の同定と機能解析
- 2000 - 2002 Diabetes as a Model for Functional Genomics in Multifactorial Diseases
- 2000 - 2001 多因子疾患糖尿病における機能ゲノム学の新展開
- 1999 - 2001 Genetic analysis of diabetes in SMXA recombinant inbred strain of mice.
- 2000 - 2000 糖尿病遺伝子の同定・単離ならびに機能解析:ヒトとモデル動物の染色体対応に基づいたアプローチ
- 1999 - 2000 Genetic analysis of insulin-dependent diabetes melliths as a multi-Factorial disease
- 1999 - 2000 CLONING OF SUSCEPTIBILITY GENES FOR TYPE 1 DIABETES MELLITUS AS A MODEL CASE FOR MULTIFACTORIAL DISEASES
- 1999 - 1999 分子ライブラリーを用いた糖尿病の病態解明ならびに治療法構築の新展開
- 1997 - 1999 Identification of susceptibility gene of diabetes mellitus y QTL analysis in the genetic modified mice.
- 1997 - 1998 CLONING OF SUSCEPTIBILITY GENES FOR NON-INSULIN-DEPENDENT DIABETES MELLITUS BY A NOVEL STRATEGY
- 1996 - 1998 DEVELOPMENT OF A NOVEL STRATEGY FOR GENETIC ANALYSIS OF MULTIFACTORIAL TRAITS USING DIABETES AS A MODEL CASE
- 1997 - 1997 新しいストラテジーに基づいた疾患関連遺伝子解析システムの開発と糖尿病への応用
- 1996 - 1996 新しいマッピング法を用いたインスリン依存性糖尿病発症遺伝子の解析
- 1994 - 1994 ポジショナルクローニングによる糖尿病発症遺伝子の解析
- 1992 - 1994 Molecular Research of the Etiology and Treatment of Hypertension
- 1993 - 1993 インスリン依存性糖尿病発症遺伝子の研究:抗原輸送担体遺伝子の解析
- 1992 - 1992 インスリン非依存性糖尿病の発症遺伝子に関する分子遺伝学的研究
- 1991 - 1991 I型糖尿病発症遺伝子に関する研究:non-MHC遺伝子座の同定
- 1990 - 1990 I型糖尿病発症遺伝子に関する研究:PCR法によるHLAクラスII遺伝子の解析
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Papers (294)：
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Naru Babaya, Shinsuke Noso, Yoshihisa Hiromine, Yasunori Taketomo, Fumimaru Niwano, Sawa Yoshida, Sara Yasutake, Yumiko Kawabata, Norikazu Maeda, Hiroshi Ikegami. Glucose values from the same continuous glucose monitoring sensor significantly differ among readers with different generations of algorithm. Scientific Reports. 2024. 14. 1
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Akira Shimada, Eiji Kawasaki, Norio Abiru, Takuya Awata, Yoichi Oikawa, Haruhiko Osawa, Hiroshi Kajio, Junji Kozawa, Kazuma Takahashi, Daisuke Chujo, et al. New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes in Japan Diabetes Society (English version). Diabetology International. 2024. 15. 1. 1-4
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Akira Shimada, Eiji Kawasaki, Norio Abiru, Takuya Awata, Yoichi Oikawa, Haruhiko Osawa, Hiroshi Kajio, Junji Kozawa, Kazuma Takahashi, Daisuke Chujo, et al. New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes of the Japan Diabetes Society (English version). Journal of Diabetes Investigation. 2024. 15. 2. 254-257
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Shuzo Imamura, Fumimaru Niwano, Naru Babaya, Yoshihisa Hiromine, Ippei Matsumoto, Keiko Kamei, Yuta Yoshida, Yasunori Taketomo, Sawa Yoshida, Yoshifumi Takeyama, et al. High Incidence of Diabetes Mellitus After Distal Pancreatectomy and Its Predictors: A Long-term Follow-up Study. The Journal of Clinical Endocrinology & Metabolism. 2023. 109. 3. 619-630
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Eiji Kawasaki, Akira Shimada, Akihisa Imagawa, Norio Abiru, Takuya Awata, Yoichi Oikawa, Haruhiko Osawa, Yumiko Kawabata, Junji Kozawa, Tetsuro Kobayashi, et al. Bivalent GAD autoantibody ELISA improves clinical utility and risk prediction for adult autoimmune diabetes. Journal of Diabetes Investigation. 2023. 14. 4. 570-581
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MISC (455)：
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Hiroshi Ikegami. Which comes first in type 1 diabetes: Autoimmunity or dysglycemia?. Journal of Diabetes Investigation. 2023. 14. 5. 645-647
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今村修三, 庭野史丸, 馬場谷成, 廣峰義久, 松本逸平, 亀井敬子, 松本正孝, 武友保憲, 吉田左和, 竹山宜典, et al. 糖尿病発症に及ぼす膵β細胞量の影響:膵切除後の前向き研究(KIP-MEP study)における体尾部切除での検討. 糖尿病. 2023. 66. Supplement1. S-316
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小谷紀子, 島田朗, 川﨑英二, 中條大輔, 霜田雅之, 粟田卓也, 寺川瞳子, 池上博司, 及川洋一, 大澤春彦, et al. 緩徐進行1型糖尿病における膵島関連自己抗体とインスリン分泌の経年的変化の検討. 糖尿病. 2023. 66. Supplement1. S-199
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川﨑英二, 粟田卓也, 池上博司, 今川彰久, 戎野朋子, 及川洋一, 大澤春彦, 香月健志, 金綱規夫, 川村良一, et al. 緩徐進行1型糖尿病における進行予測に関する検討(TIDE-J研究). 糖尿病. 2023. 66. Supplement1. S-199
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長江亮太, 橘恵, 今川彰久, 小谷紀子, 阿比留教生, 粟田卓也, 池上博司, 岩橋博見, 及川洋一, 大澤春彦, et al. 1型糖尿病発症後のプロインスリン濃度-日本人1型糖尿病の包括的データベースの構築と臨床研究への展開-. 糖尿病. 2023. 66. Supplement1. S-153
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Books (162)：
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<作成委員>高齢者糖尿病診療ガイドライン2023[日本老年医学会・日本糖尿病学会 編・著]
南江堂 2023 ISBN:9784524234646
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Biomarkers in Disease: Methods, Discoveries and Applications. Biomarkers in Diabetes
Springer 2022
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内科学 第12版
朝倉書店 2022 ISBN:9784254322804
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糖尿病の?がわかる!イラストBOOK-「あなた糖尿病ですよ」と告げられたら
メディカ出版 2022 ISBN:9784840478274
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糖尿病最新の治療2022-2024
南江堂 2021 ISBN:9784524229963
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Lectures and oral presentations (701)：
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糖尿病発症に及ぼす膵β細胞量の影響:膵切除後の前向き研究(KIP-MEP study)における体尾部切除での検討
(第66回日本糖尿病学会年次学術集会 2023)
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緩徐進行1型糖尿病における膵島関連自己抗体とインスリン分泌の経年的変化の検討
(第66回日本糖尿病学会年次学術集会 2023)
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緩徐進行1型糖尿病における進行予測に関する検討(TIDE-J研究)
(第66回日本糖尿病学会年次学術集会 2023)
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受賞講演(ハーゲドーン賞) 「1型糖尿病に関する分子遺伝学的研究」
(第66回日本糖尿病学会年次学術集会 2023)
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1型糖尿病発症後のプロインスリン濃度-日本人1型糖尿病の包括的データベースの構築と臨床研究への展開-
(第66回日本糖尿病学会年次学術集会 2023)
ｍore...
Education (2)：
- 1981 - 1985 Osaka University Graduate School of Medicine
- 1975 - 1981 Osaka University Medical School
Professional career (2)：
- Doctor of Philosophy (Osaka University)
- M.D.(Doctor of Medicine) (Osaka University)
Work history (3)：
- 2006 - 現在 Kindai University Faculty of Medicine
- 2002 - 2006 Osaka University Graduate School of Medicine associate professor
- 1989 - 2002 Osaka University Medical School assisstant professor
Awards (7)：
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