Rchr
J-GLOBAL ID:201401020326889074   Update date: May. 12, 2026

Tsuchiya Kohsuke

ツチヤ コウスケ | Tsuchiya Kohsuke
Affiliation and department:
Research field  (3): Immunology ,  Bacteriology ,  Tumor biology
Research theme for competitive and other funds  (10):
  • 2023 - 2027 Functional Analysis and Applications of A Novel Pattern Recognition Receptor Recognizing Bacterial-Derived Molecules
  • 2023 - 2027 細菌由来分子を認識する新たなパターン認識受容体の機能解析と応用
  • 2022 - 2025 Identification of Bacterial and Fungal Proteases that Activate Gasdermin Family Molecules to cause Pyroptosis
  • 2020 - 2023 パイロトーシス細胞が放出するリステリア増殖抑制因子の解析
  • 2018 - 2021 Host-pathogen interactions in antibiotic therapy for listeriosis
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Papers (48):
  • Kohsuke Tsuchiya, Shoko Hosojima, Shenghui Zhi, Yamato Tanabe, Takeshi Kinoshita, Takashi Suda. Sublethal Disulfide Stress Facilitates TLR2-Dependent NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Cells. 2026
  • Takeshi Kinoshita, Kohsuke Tsuchiya, Daisuke Inoue, Shinsuke Nakajima, Yutaka Suzuki, Takashi Suda. The kinesin motor KIF11 coordinates NLR localization and activation in the innate immune response. 2026
  • Yuka Inaba, Kohsuke Tsuchiya, Hiroshi Inoue. Shifting cell death modes in hepatic steatosis: from apoptosis to necroptosis. Endocrine Journal. 2026. 73. 1. 13-20
  • Eduardo Hernández-Cuellar, Kohsuke Tsuchiya, Oscar Medina-Contreras, Ricardo Valle-Ríos. The Role of Inflammasomes in LPS and Gram-Negative Bacterial Sepsis. Journal of clinical medicine. 2025. 14. 19
  • Kentaro Hirade, Noritaka Tanaka, Taisuke Kajino, Yuta Adachi, Ryo Kimura, Hitomi Kasuya, Satoru Kisoda, Tze King Tan, Sho Hayakawa, Takahiko Sato, et al. Inhibiting KRAS with CD47 and immune checkpoint overcomes intrinsic resistance to combined KRAS and immune checkpoint inhibitor therapy. Cell reports. Medicine. 2025. 6. 9. 102317-102317
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MISC (10):
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Books (3):
  • 細胞質内リステリアの認識に関わる新規分子AIM2
    医学の門社 2011
  • AIM2(absent in melanoma 2)はインフラマソームの活性化に関与する
    金原一郎記念医学医療振興財団 2011
  • リステリア溶血毒素タンパクが示す新規活性
    医薬ジャーナル社 2009
Professional career (1):
  • 医学博士 (京都大学)
Committee career (1):
  • 2022/01 - 現在 Microbiology and Immunology誌:Associate Editor
Awards (1):
  • 2012 - 日本生体防御学会・奨励賞
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