Rchr
J-GLOBAL ID:201401020326889074   Update date: Jul. 19, 2021

Tsuchiya Kohsuke

ツチヤ コウスケ | Tsuchiya Kohsuke
Affiliation and department:
Job title: 准教授
Research field  (3): Immunology ,  Bacteriology ,  Tumor biology
Research theme for competitive and other funds  (7):
  • 2020 - 2023 パイロトーシス細胞が放出するリステリア増殖抑制因子の解析
  • 2018 - 2021 Host-pathogen interactions in antibiotic therapy for listeriosis
  • 2014 - 2019 Molecular mechanisms and roles of pyroptosis
  • 2014 - 2018 Caspase-1-independent roles for inflammasome-forming proteins in bacterial infections
  • 2011 - 2015 Role of the inflammasome in bacterial infections
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Papers (38):
  • Takayuki Uematsu, Kohsuke Tsuchiya, Noritada Kobayashi, Motoharu Seiki, Jun ichiro Inoue, Shuichi Kaneko, Takeharu Sakamoto. Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages. Cell Death and Disease. 2021. 12. 4
  • Kohsuke Tsuchiya, Shoko Hosojima, Hideki Hara, Hiroko Kushiyama, Mamunur Rashid Mahib, Takeshi Kinoshita, Takashi Suda. Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes. Cell Reports. 2021. 34. 12
  • Kohsuke Tsuchiya. Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor Immunity. International journal of molecular sciences. 2021. 22. 1
  • Ayumi Saeki, Kohsuke Tsuchiya, Takashi Suda, Takeshi Into, Akira Hasebe, Toshihiko Suzuki, Ken-ichiro Shibata. Gasdermin D-independent release of interleukin-1 β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides. Immunology. 2020. 161. 2. 114-122
  • Mamunur Rashid Mahib, Shoko Hosojima, Hiroko Kushiyama, Takeshi Kinoshita, Toshihiko Shiroishi, Takashi Suda, Kohsuke Tsuchiya. Caspase-7 mediates caspase-1-induced apoptosis independently of Bid. Microbiology and Immunology. 2020
more...
MISC (1):
Books (3):
  • 細胞質内リステリアの認識に関わる新規分子AIM2
    医学の門社 2011
  • AIM2(absent in melanoma 2)はインフラマソームの活性化に関与する
    金原一郎記念医学医療振興財団 2011
  • リステリア溶血毒素タンパクが示す新規活性
    医薬ジャーナル社 2009
Professional career (1):
  • 医学博士 (京都大学)
Awards (1):
  • 2012 - 日本生体防御学会・奨励賞
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