Rchr
J-GLOBAL ID:201401024021398130
Update date: May. 16, 2024
IYORI MITSUHIRO
イヨリ ミツヒロ | IYORI MITSUHIRO
Affiliation and department:
Job title:
Professor
Other affiliations (1):
-
Kanazawa University
Institute of Medical, Pharmaceutical and Health Sciences Faculty of Pharmacy
Research collaborator
Research field (4):
Parasitology
, Immunology
, Pharmaceuticals - health and biochemistry
, Applied microbiology
Research keywords (6):
血清疫学
, 抗血小板薬
, Viral vectors
, Mosquitoes
, Vaccine
, Malaria
Research theme for competitive and other funds (24):
- 2022 - 2025 Development of Plasmodium vivax vaccine effective both for protection and transmission blocking
- 2021 - 2024 インドネシア人の血清疫学調査に基づくCOVID-19ワクチンの開発研究
- 2021 - 2024 認可済みウイルスベクターを基盤とした感染防御-伝搬阻止マラリアワクチンの開発研究
- 2019 - 2022 Evaluation of innate immune resonses induced by baculovirus against malaria liver-stage parasites
- 2020 - 2022 Made-in-Japan next-generation vaccine platform effective for multistage Plasmodium for infants
- 2020 - 2022 次世代マラリアワクチンの探索
- 2018 - 2021 The development of a novel vaccine vector by the heterologous prime-boost immunization regimen
- 2019 - 2021 臨床応用を目指したアデノ随伴ウイルスを用いた熱帯熱マラリア2価ワクチンの開発研究
- 2018 - 2020 Development of a new immunostimulatory drug for non-haemolytic alternative to PQ.
- 2016 - 2019 Development of a new evaluation tool for measuring malaria infection risk based on antibody responses to Anopheles saliva protein
- 2015 - 2018 Malaria vaccine development based on multifunctional hybrid vaccine platform
- 2016 - 2018 臨床試験に向けての新規マラリアワクチンBDES-NPVの製造プロセスと品質管理に関する研究
- 2015 - 2017 Anopheline anti-platelet protein, AAPP, regulates probing time and blood feeding success in the malaria vector mosquito, Anopheles stephensi
- 2014 - 2017 The development of malaria vaccine platform using baculovirus regulating immune responses
- 2016 - 2017 マラリアワクチン開発を基盤とした新規感染症用ワクチンプラットフォームの創出 -非感染性バキュロウイルスナノ粒子ワクチンシステムの開発研究
- 2013 - 2016 IgG responses to mosquito saliva proteins for evaluating human exposure to Anopheles bites
- 2015 - 2016 非感染性ウイルスナノ粒子ワクチンを用いたマラリアワクチン開発
- 2014 - 2016 補体抵抗性を付与した新型マラリアワクチンベクターの開発
- 2012 - 2014 Development of a novel anti-platelet drug targeted for collagen-induced platelet aggregation
- 2013 - 2014 抗蚊唾液抗体価を用いたマラリア疫学調査の新規評価法の開発
- 2012 - 2013 出血助長の副作用を回避した新規低分子化ペプチドの抗血小板薬開発研究
- 2012 - 2013 新規マラリアワクチンベクター Baculovirus Triple Expression Systemの研究開発
- 2011 - 2012 吸血昆虫由来の新規ペプチドを基盤とした抗血小板薬の開発
- 2008 - 2009 Toll様受容体とナチュラルキラー細胞受容体とのクロストーク
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Papers (30):
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Yutaro Yamamoto, Camila Fabbri, Daiki Okuhara, Rina Takagi, Yuna Kawabata, Takuto Katayama, Mitsuhiro Iyori, Ammar A. Hasyim, Akihiko Sakamoto, Hiroaki Mizukami, et al. A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study. Frontiers in Immunology. 2024. 15
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Sitti Nurisyah, Mitsuhiro Iyori, Ammar A. Hasyim, Akihiko Sakamoto, Hinata Hashimoto, Kyouhei Yamagata, Saya Yamauchi, Khaeriah Amru, Kartika H. Zainal, Irfan Idris, et al. Comparison between neutralization capacity of antibodies elicited by COVID-19 natural infection and vaccination in Indonesia: A prospective cohort. Antibodies. 2023. 12. 3. 60
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水野 哲志, Andrew Blagborough, 新倉 保, 伊從 光洋, 水上 浩明, 志田 壽利, 吉田 栄人. 複数ライフステージをワクチンターゲットにした熱帯熱マラリアワクチンの開発. 臨床とウイルス. 2023. 51. 3. 126-126
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Nobuko Tuno, Thahsin Farjana, Yui Uchida, Mitsuhiro Iyori, Shigeto Yoshida. Effects of Temperature and Nutrition during the Larval Period on Life History Traits in an Invasive Malaria Vector Anopheles stephensi. Insects. 2023. 14. 6
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Mitsuhiro Iyori, Andrew M. Blagborough, Tetsushi Mizuno, Yu-ichi Abe, Mio Nagaoka, Naoto Hori, Iroha Yamagoshi, Dari F. Da, William F. Gregory, Ammar A. Hasyim, et al. Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study. Frontiers in Immunology. 2022. 13. 1005476-1005476
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MISC (9):
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Mitsuhiro Iyori, Andrew M. Blagborough, Sota Ogata, Hidesato Nishiura, Miako Sakaguchi, Masanori Mizutani, Takahiko Tamura, Kento Genshi, Satoshi Shimada, Daisuke S. Yamamoto, et al. VECTORED PFCSP VACCINES BASED ON BACULOVIRUS DUAL EXPRESSION SYSTEM AND ADHU5 INDUCE STRONG PROTECTIVE EFFICACY AGAINST TRANSGENIC PLASMODIUM BERGHEI. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2017. 95. 5. 125-125
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Kunitaka Yoshida, Ahmed M. Salman, Pawan Dulal, Shahid M. Khan, Chris J. Janse, Sumi Biswas, Masaharu Tokoro, Mitsuhiro Iyori, Shigeto Yoshida, Adrian V. S. Hill. ENHANCED PROTECTIVE EFFICACY OF A PLASMODIUM FALCIPARUM MALARIA VACCINE USING A HETEROLOGOUS PRIME-BOOST IMMUNIZATION WITH A BACULOVIRAL VACCINE AND CHAD63 EXPRESSING PFCSP AGAINST CHALLENGE WITH TRANSGENIC P. BERGHEI SPOROZOITES. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2017. 95. 5. 314-314
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Mitsuhiro Iyori, Risa Fujiyoshi, Din Syafrudin, Shigeto Yoshida. DIFFERENTIAL ANTIBODY RESPONSE TO THE ANOPHELES STEPHENSI AAPP AND PLASMODIUM ANTIGENS IN INDIVIDUALS NATURALLY EXPOSED TO BITES OF AFROTROPICAL MALARIA VECTORS. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2015. 93. 4. 114-114
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Mohammad Shamsul Haque, 長谷部 晃, 伊従 光洋. Clathrin-dependent endocytosis of the TLR2 ligand FSL-1 triggered by CD14 and CD36 but not by TLR2 (第36回日本マイコプラズマ学会学術集会). 日本マイコプラズマ学会雑誌. 2009. 36. 1-3
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OHTANI Makoto, IYORI Mitsuhiro, HASEBE Akira, KIURA Kazuto, TOTUKA Yasunori, SHIBATA Ken-ichiro. Cross talk between Toll-like receptor 2- and DC-SIGN-mediated signaling pathways. 2008. 35. 65-66
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Lectures and oral presentations (163):
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ブラジルでの三日熱マラリア伝播阻止ワクチン評価〜Anopheles darlingiとAn. aquasalisでのオオシスト形成阻害〜
(第76回日本衛生動物学会大会 2024)
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三日熱マラリアユニーバーサルワクチン開発(マウスモデル)-3種のPvCSP変異型アレルに対応-
(第93回日本寄生虫学会大会 2024)
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A Replication-Competent Vaccinia Virus LC16m8∆2/AAV1-Based malaria vaccine versus RTS, S/AS01E in a Murine Model
(第93回日本寄生虫学会大会 2024)
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Development of Epitope-Lacking Transgenic Rodent Malaria Parasite as an Approach for Assessing Vaccine Mechanism of Protection
(第93回日本寄生虫学会大会 2024)
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Analysis of gene expression in the liver stimulated by baculovirus for killing the liver-stage Plasmodium
(The 16th Asian-Pacific Congress for Parasitic Zoonoses 2023)
more...
Education (2):
- 2005 - 2009 Hokkaido University Graduate School of Dental Medicine
- 1998 - 2005 Hokkaido University School of Dental Medicine
Work history (6):
Committee career (6):
Awards (1):
- 2009/03 - 北海道大学大学院歯学研究科 北海道歯学会賞
Association Membership(s) (6):
日本薬学会
, 日本衛生動物学会
, 日本寄生虫学会
, 日本免疫学会
, 日本マイコプラズマ学会
, 日本細菌学会
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